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26,715 recruiting studies available now

Natural History of Trisomy 8-Associated Autoinflammatory Disease (TRIAD) and Related Disorders

Background: Trisomy 8 mosaicism is a genetic disorder that can increase inflammation in the body. Symptoms include fevers; sores or ulcers in the mouth, diges…

Trisomy 8 MosaicismTrisomy 8 Associated Autoinflammatory DiseaseMucosal Ulcerations

Estimated

~$10 – $675

National Institute of Allergy and Infectious Diseases (NIAID)NCT07683104

Phase 2

Phase II, Randomized, Double-Blind, Placebo-Controlled Trial of Omega-3 Fatty Acid (O3FA) Supplementation for Adult and Juvenile Dermatomyositis (DM/JDM)

Dermatomyositis (DM) is a rare autoimmune disease that causes muscle weakness, skin rashes, and other symptoms. Researchers think both genetic and environmenta…

Dermatomyositis (DM)Juvenile Dermatomyositis (JDM)

Estimated

~$10 – $5,625

National Institute of Environmental Health Sciences (NIEHS)NCT07111065

Phase 1

A Phase I Study to Assess the Safety and Antitumor Activity of Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease

Background: Small cell lung cancer (SCLC) is the deadliest form of lung cancer. Extrapulmonary neuroendocrine cancer (EPNEC) is a similar type of cancer that …

Extensive-Stage Small Cell Lung CancerExtrapulmonary Neuroendocrine CarcinomaRecurrent or Refractory+1 more

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT07509034

Phase 3

A Randomised, Double-blind, Placebo-controlled, Multicentre, Phase III Trial Evaluating Long-term Efficacy and Safety of Survodutide Weekly Injections in Adult Participants With Noncirrhotic Non-alcoholic Steatohepatitis/Metabolic Dysfunction-associated Steatohepatitis (NASH/MASH) and (F2) - (F3) Stage of Liver Fibrosis

This study is open to adults who are at least 18 years old living with obesity and have: * a confirmed liver disease called non-alcoholic steatohepatitis (NAS…

Metabolic Dysfunction Associated Steatohepatitis (MASH)Liver Fibrosis

Estimated

~$10 – $7,500

Boehringer IngelheimNCT06632444

Phase 1

Phase I/ II Study of Pulmonary Suffusion to Control Minimal Residual Disease in Resectable or Ablatable Sarcoma or Colorectal Pulmonary Metastases

This phase I/II trial studies the side effects of pulmonary suffusion in controlling minimal residual disease in patients with sarcoma or colorectal carcinoma …

Metastatic Bone SarcomaMetastatic Malignant Neoplasm in the LungMetastatic Soft Tissue Sarcoma+3 more

Estimated

~$10 – $7,500

Roswell Park Cancer InstituteNCT03965234

Phase 2

A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study With a Separate Open-label Cohort to Evaluate the Efficacy and Safety of Brenipatide as Adjunctive Treatment to Transmucosal Buprenorphine With or Without Naloxone in Early Recovery of Participants With Opioid Use Disorder (RENEW-Op-1)

The purpose of this study is to see if brenipatide, when compared to placebo, is safe and effective for participants with opioid use disorder, when used with b…

Opioid Use Disorder

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07420283

Observational

Physiology of Liberation

This academic study examines how everyday experiences are related to short-term physiological reactivity and recovery and whether one or more brief standardize…

Psychophysiological Reactivity and Recovery

Estimated

~$10 – $6,250

Boston University Charles River CampusNCT07780266

Observational

Impact of the EpiFaith® Syringe on the Learning Curve of Anesthesia Residents for the Labor Epidural Technique: A Quasi-Experimental Study

This study aims to evaluate the impact of the EpiFaith® syringe on the learning curve of anesthesia residents for the labor epidural technique. Anesthesia resi…

Epidural AnalgesiaEpidural Analgesia for Labour and DeliveryLearning Curve

Estimated

~$10 – $6,250

Brigham and Women's HospitalNCT07395622

Phase 3

Randomized, Phase III Study of Early Intervention With Venetoclax and Obinutuzumab Versus Delayed Therapy With Venetoclax and Obinutuzumab in Newly Diagnosed Asymptomatic High-Risk Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): EVOLVE CLL/SLL Study

This phase III trial compares early treatment with venetoclax and obinutuzumab versus delayed treatment with venetoclax and obinutuzumab in patients with newly…

Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT04269902

Discovering Determinants of Food Intake by Application of Machine Learning to Complex, High-Dimensional Data

Background: Many people in the United States are overweight or obese. Researchers want to learn why some people can overeat and not gain weight, whereas other…

Healthy Volunteer

Estimated

~$10 – $675

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT07637656

Phase 3

A Phase 3, Multicenter, Randomized, Double-Blind Study to Investigate the Efficacy and Safety of Brenipatide Compared With Placebo for the Treatment of Adult Participants With Alcohol Use Disorder (RENEW-ALC-2)

The purpose of this study is to see if brenipatide when compared to a placebo works and is safe for participants with Alcohol Use Disorder (AUD) and hazardous …

Alcohol Use Disorder

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07219953

Phase 4

Ultrasound Therapy In Cardiac Amyloidosis

This is a prospective pilot clinical study of subjects with cardiac amyloidosis and control subjects without amyloidosis where we plan to evaluate changes in m…

Amyloidosis Cardiac

Estimated

~$10 – $6,250

Brigham and Women's HospitalNCT04667494