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OPTIMUS PRIME: Safety and Feasibility of OPTune GIO® Integrated With MRI-gUided Laser Ablation Surgery and Pembrolizumab for Recurrent GlIoblastoMa, A randomizEd Trial

In this study we are evaluating the safety and feasibility of the triple combination (TTFields, MLA, pembrolizumab) in adult patients diagnosed with recurrent …

Recurrent Glioblastoma

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of FloridaNCT06558214

Phase 2

Clinical Study to Assess Tolnaftate 1% With a Novel Vehicle for the Treatment of Tinea Pedis

This study is designed to evaluate the safety and effectiveness of multiple 1% tolnaftate formulations delivered through novel stick-based vehicles in individu…

Tinea Pedis

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Propedix, Inc.NCT07245667

Phase 1

A Phase I/II Study of Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab in Advanced Solid Tumors (PNeoVCA)

This phase I/II trial tests the safety and tolerability of an experimental personalized vaccine when given by itself and with pembrolizumab in treating patient…

Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8+98 more

Phase 4

Effect of Varenicline on Smoking Cessation in Patients With Schizophrenia: Evaluation of Antipsychotic Drug-Induced Neurological Symptoms as Correlates of Response

To test the feasibility of studying effects of smoking cessation with varenicline on antipsychotic drug-induced neurological side effects, we propose a 12 week…

SchizophreniaSchizoaffective DisorderTobacco Smoking+2 more

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Corporal Michael J. Crescenz VA Medical CenterNCT03495024

Observational

Effect of a Technology-based Collaborative Model on Persistent Hypertension and Preventive Care Attendance Among Postpartum People With Hypertensive Disorders of Pregnancy

This is a hybrid type 1 non-inferiority implementation effectiveness trial among postpartum patients with hypertension (N=1536) that will test the hypothesis t…

Hypertension in PregnancyPostpartum PreeclampsiaPostpartum Complication

Estimated

~$10 – $750

Actual pay is set by the research site.

Women and Infants Hospital of Rhode IslandNCT06842875

Preventing Type 2 Diabetes Following Gestational Diabetes: Implementation Mapping for a Multilevel Breastfeeding Support Strategy

The investigators will use implementation methods to develop better breastfeeding support for patients with gestational diabetes as a way to prevent type 2 dia…

Gestational Diabetes Mellitus (GDM)Diabetes Type 2Breastfeeding Continuation+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of California, DavisNCT07176793

Observational

Hearing Loss and Brain Health Study

Hearing loss is a prevalent and modifiable risk factor for cognitive decline and dementia in older adults, yet access to hearing care remains limited. Over-the…

Hearing Loss, Adult-OnsetDementia

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Southern CaliforniaNCT07288463

Observational

Locomotion Adaptation Deficits in Older Adults With Mild Cognitive Impairment and Alzheimers Disease

In people with Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD), reduced capacity for locomotor adaptation is a fundamental but poorly understood m…

Alzheimers DiseaseMild Cognitive Impairment

Estimated

~$10 – $750

Actual pay is set by the research site.

Emory UniversityNCT06484244

Phase 2

Phase II Trial of Normal Tissue Sparing Whole Brain Radiation Therapy (NTS-WBRT) in Patients With Brain Metastases

This research is being done to assess the quality of life and symptom burden in participants who receive (normal tissue sparing whole brain radiation therapy (…

Brain Metastases

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Massachusetts General HospitalNCT05013892

Pathophysiological Evaluation of Idiopathic Intracranial Hypertension Using Glymphatic and Connectomic Imaging

Idiopathic intracranial hypertension (IIH) is characterized by elevated intracranial pressure leading to symptoms like papilledema, headache, and cognitive dys…

Idiopathic Intracranial Hypertension (IIH)Glymphatic System

Estimated

~$10 – $750

Actual pay is set by the research site.

Thomas Jefferson UniversityNCT06950099

Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome

This research will have a significant impact on the overall management of those cancer patients and their family members who are at risk for hereditary cancer …

Uveal MelanomaCutaneous MelanomaBAP1 Gene Mutation+5 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Mohamed Abdel-RahmanNCT04792463

Phase 1

An Open-Label, Multiple-Center, Phase I/II Dose Escalation Study for the Safety and Efficacy of NGGT002 in Adults With Classic Phenylketonuria

This is a Phase 1/2, open-label, multiple-center, dose escalation and cohort expansion study to evaluate the safety and efficacy of NGGT002 in adult subjects w…

Phenylketonurias

Estimated

~$150 – $4,200

Actual pay is set by the research site.

NGGT INC.NCT06332807