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Impact of Low Pressure Pneumoperitoneum on Postoperative Ileus and Gastrointestinal Dysfunction in Patients Undergoing Laparoscopic Large Bowel Surgery

The investigators are testing the hypothesis that lower pressure pneumoperitoneum during laparoscopic large bowel surgery protects the bowel from postoperative…

Postoperative IleusGastrointestinal Dysfunction

Estimated

~$10 – $6,250

Ohio State UniversityNCT05344417

Phase 1

A Phase 1b Study to Assess the Safety, Tolerability and Pharmacokinetics of OPT101 in Patients With Community Acquired Pneumonia (CAP) With Sepsis

OPT101-100-40 is a multicenter, randomized, placebo-controlled, multiple-ascending-dose, sequential-group, investigator- and participant-blinded, sponsor-unbli…

SepsisCommunity Acquired Pneumonia (CAP)

A Randomized Phase 2 Study to Evaluate the Efficacy and Safety for Adjuvant Therapeutic Cancer Vaccine (AST-201, pUMVC3-hIGFBP-2) in Patients With Advanced Ovarian Cancer (Cornerstone-004)

The purpose of this phase 2 study is to assess the efficacy and safety for adjuvant therapeutic cancer vaccine AST-201 (pUMVC3-hIGFBP-2) in patients with newly…

Advanced Ovarian Cancer

Estimated

~$10 – $8,750

Aston Sci. Inc.NCT05794659

Observational

MR Evaluation of Cerebrospinal Fluid (CSF) Dynamics and Association of Intracranial CSF Flow With Brain Function

The Researchers are trying to test a MR imaging method for detection of Cerebral Spinal Fluid (CSF) flow in the brain to help diagnosis and better understand d…

HydrocephalusAlzheimer Disease

Estimated

~$10 – $6,250

Mayo ClinicNCT04099823

Phase 2

Infusion of Convalescent Plasma for the Treatment of Patients Infected With Severe Acute Respiratory Syndrome-Coronavirus-2 (COVID-19): A Double-blinded, Placebo-controlled, Proof-of-concept Study

Patients who are ill with COVID-19 may benefit from receiving convalescent plasma infusions containing antibodies from donors who have recovered from the disea…

COVID-19

Estimated

~$10 – $6,250

University of Illinois at ChicagoNCT04442191

Observational

Conservative Versus Operative Management of First Time Shoulder Dislocations

There is no consensus regarding whether rehabilitation or surgical stabilization leads to optimized outcomes for treatment of primary anterior shoulder disloca…

Shoulder Dislocation

Estimated

~$10 – $6,250

Columbia UniversityNCT05532150

Phase 1

A First in Human, Double-Blind, Placebo-Controlled, Randomized Evaluation of Single Ascending Doses of ATI-1013, a Human Monoclonal Antibody to Nicotine in Healthy Smokers

This study is a first-in-human clinical trial of drug ATI-1013, in healthy adult cigarette smokers. The main questions it aims to answer are to learn about the…

Thromboangiitis Obliterans (Buerger's Disease)

Estimated

~$10 – $8,750

Antidote Therapeutics, IncNCT07215923

Phase 4

Upper Extremity Injection of Xeomin® and Changes in Gait Related Mobility in Adults After Stroke

The aim of the present pilot study is to evaluate the association between change in gait related mobility in ambulatory male and female adult hemiparetic patie…

Stroke

Estimated

~$10 – $6,250

Wake Forest University Health SciencesNCT04908423

Phase 1

A Phase 1b/2, Open-label Study to Investigate the Safety and Efficacy of Invikafusp Alfa (STAR0602), a Selective T Cell Receptor (TCR)-Targeting, Bifunctional Antibody-fusion Molecule, in Combination With Sacituzumab Govitecan in Participants With Unresectable, Locally Advanced, or Metastatic Solid Tumors (START-002)

This is a Phase 1b/2, Open-label Study to Investigate the Safety and Efficacy of Invikafusp alfa (STAR0602), a Selective T Cell Receptor (TCR)-targeting, Bifun…

Triple Negative Locally Advanced Non-resectable Breast CancerHR+, HER2-, Advanced Breast Cancer

Estimated

~$10 – $8,750

Marengo Therapeutics, Inc.NCT06827613

Correlation of Serum Vitamin D Level With the Development of Endocrine Autoimmune Complications During Treatment With Immune Checkpoint Inhibitors

The purpose of this research study is to see if the amount of vitamin D in ones blood makes it more or less likely to develop thyroid gland toxicity when being…

ThyroidPD-1Cancer

Estimated

~$10 – $750

Icahn School of Medicine at Mount SinaiNCT04615988

Observational

Text-messaging E-cigarette Cessation Intervention for Young Adults in Rural Areas: A Pilot Study

This is a small pilot randomized controlled trial to evaluate the feasibility, acceptability, and preliminary efficacy of the e-cigarette cessation text-messag…

E-cigarette Use

Estimated

~$10 – $7,500

Jovan Gwon, PhD, RN, FIAANNCT05906082

FILTER - Filter Initial & Long Term Evaluation After Placement and Retrieval (Including Laser-Assisted Retrieval) Prospective Registry

A prospective data registry for all patients who undergo IVC (Inferior Vena Cava) filter placement or retrieval at Stanford. Potential enrollees will already b…

Venous Thromboembolism

Estimated

~$10 – $750

Stanford UniversityNCT01158482