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27,295 recruiting studies available now

A Longitudinal Natural History Study of Immune Biomarkers in Neuropsychiatric Illness

Background: Some brain or mental health conditions may be caused when a person s immune system attacks their own body. These are called immunologic neuropsych…

Neuropsychiatric DisordersNeuroinflammatory DisordersPost-Infectious Neuropsychiatric Disorders

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Mental Health (NIMH)NCT07877246

Studies of the Natural History, Pathogenesis, and Outcome of Idiopathic Systemic Vasculitis

Background: \- Vasculitis is a group of diseases that inflame and damage blood vessels and tissue. It can cause many medical problems. Few tests can diagnose …

Takayasu's ArteritisGiant Cell ArteritisPolyarteritis Nodosa+2 more

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)NCT02257866

Phase 2

A Phase 2 Dose-Finding Study to Assess the Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

Obesity is a condition where a person has excessive body fat, defined by a body mass index (BMI) of 30 kg/m2 or higher. The goal of this study is to evaluate t…

ObesityOverweight

Estimated

~$75 – $3,000

Actual pay is set by the research site.

AbbVieNCT07752979

Pain Phenotyping of Rheumatic Diseases - An Observational Study

Background: Rheumatic diseases can affect the joints, ligaments, tendons, bones, muscles, and skin. They can also cause inflammation, damage body tissues, and…

Rheumatic DiseasesLupus Erythematosus, SystemicLupus Vasculitis, Central Nervous System+5 more

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)NCT07829497

Observational

FITting Non-invasive Testing Into Lynch Syndrome Colorectal Cancer Surveillance: a Multi-center, Prospective Study

The purpose of this clinical study is to evaluate the accuracy of the fecal immunochemical test (FIT) in comparison to colonoscopy in patients with Lynch Syndr…

Colorectal Cancer

Estimated

~$10 – $750

Actual pay is set by the research site.

University of ChicagoNCT06898996

Phase 4

A Single-arm Open-label Safety Study of SMOFlipid to Evaluate the Risk of Developing Essential Fatty Acid Deficiency (EFAD) and/or Parenteral Nutrition-associated Cholestasis (PNAC) in Pediatric Patients 1 Month to 17 Years of Age and in Adult Patients, Who Are Anticipated to Need 8 Weeks or Longer of Parenteral Nutrition Treatment

Evaluate the risk of developing EFAD and/or PNAC in adult and pediatric patients 1 month of age and older, who are anticipated to need 8 weeks or longer of par…

Malnutrition, ChildMalnutritionEssential Fatty Acid Deficiency (EFAD)+1 more

Estimated

~$25 – $1,500

Actual pay is set by the research site.

Fresenius KabiNCT06049680

Multi-center, Single-arm, Observational Study Assessing Real-world Safety and Performance of the TRIFORMIS RESILIA Tricuspid Valve for Surgical Tricuspid Valve Replacement (TRIBLAZE Study)

TRIBLAZE is a prospective, observational, single-arm, multicenter study designed to collect real-world clinical outcomes in a minimum of 75 participants who wi…

Heart Valve DiseasesHeart DiseasesCardiovascular Diseases+1 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Edwards LifesciencesNCT07684313

Phase 3

A Long-Term Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Multiple Maintenance Doses of Oral Once Daily Aleniglipron for Chronic Weight Management in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

This is randomized, double-blind, placebo-controlled study of the long-term efficacy, safety, and tolerability of multiple doses of aleniglipron in participant…

ObesityOverweightChronic Weight Management+1 more

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure TherapeuticsNCT07654374

Wearable Sensor Platform to Monitor Stroke Recovery During Inpatient Rehabilitation

This observational trial seeks to assess the feasibility of using non-invasive, portable, real-time body-worn sensors to continuously monitor, quantify, and in…

Stroke

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Shirley Ryan AbilityLabNCT04219670

Observational

Feasibility and Preliminary Effectiveness of HABIT-ILE + Functional Strength Training in Children With Spinal Muscular Atrophy (SMA): a Prospective Single-group Intervention Trial.

This single-arm pilot study will assess the preliminary effectiveness of an intensive motor skill intervention (HABIT-ILE) combined with functional strength tr…

Spinal Muscular Atrophy (SMA)

Estimated

~$10 – $750

Actual pay is set by the research site.

Teachers College, Columbia UniversityNCT07488338

Phase 3

A Phase 3, Randomized, Open-label Study of Raludotatug Deruxtecan (MK-5909, R-DXd) Maintenance Treatment With or Without Bevacizumab Versus Standard of Care in Participants With Newly-Diagnosed Advanced Non-HRD-Positive Ovarian Cancer Following First-line Platinum-based Chemotherapy (ENGOT-ov102/MITO/GOG-3141/ REJOICE-Ovarian 04)

Researchers are looking for new ways to treat ovarian cancer (OC). Current treatment for OC may start with surgery to remove as much of the cancer as possible.…

Ovarian CancerOvarian NeoplasmsPeritoneal Cancer+1 more

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Merck Sharp & Dohme LLCNCT07776691

Phase 1

Phase 1, Open Label, Dose Escalation Study to Evaluate the Safety, Expansion, Persistence, and Preliminary Clinical Activity of Autologous CD64 CAR T Cells in Patients With Relapsed and/or Refractory Acute Myeloid Leukemia (AML)

This is a Phase 1, open label, dose-escalation study to evaluate the safety, expansion, persistence, and preliminary clinical activity of lentivirally transduc…

Refractory Acute Myeloid Leukemia (AML)Relapsed Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome+1 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of Colorado, DenverNCT07347418