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27,295 recruiting studies available now

LIGHTBEAM-U01 Substudy 01D: A Phase 1b/2 Substudy to Evaluate the Safety and Efficacy of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors

Researchers are looking for new ways to treat children with relapsed or refractory solid tumors: * Relapsed means the cancer came back after treatment * Refra…

Malignant Neoplasm

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Merck Sharp & Dohme LLCNCT07630974

Observational

An Open-Label Feasibility Trial to Assess the Efficacy of the Magnus Neuromodulation System With Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT)® Technology to Treat Memory Deficits in Older Patients With Treatment-Resistant Depression

The goal of this clinical trial is to learn whether Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT®), a type of transcranial magnetic stimulat…

Depressive Disorder, Treatment-ResistantMemory Deficits

Estimated

~$10 – $1,050

Actual pay is set by the research site.

BrainHealth Solutions, Inc.NCT07876908

Phase 3

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma

The objective of this study is to assess the potential for GB-0895 to improve the health of adolescents and adults with severe asthma that is uncontrolled by i…

Severe Asthma

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Generate BiomedicinesNCT07276724

Circulating Tumor Cell Analysis in Patients With Localized Prostate Cancer Undergoing Prostatectomy

This study will evaluate a method to detect tumor cells that are circulating in the blood without getting a biopsy. The investigators already know from other s…

Prostate Cancer

Estimated

~$10 – $750

Actual pay is set by the research site.

Massachusetts General HospitalNCT01961713

Phase 1

A Two-Part Open-Label Study of REGV131-LNP1265, A CRISPR/Cas9 Based Coagulation Factor IX Gene Insertion Therapy in Participants With Hemophilia B

Participants in this study have a genetic mutation, specifically in the coagulation (blood clotting) Factor 9 gene that causes severe or moderately severe hemo…

Hemophilia B

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Regeneron PharmaceuticalsNCT06379789

Phase 3

A Double-Masked, Randomized, Placebo-Controlled, Paired-Eye Study to Evaluate the Efficacy, Safety and Tolerability of Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Due to the c.2991+1655A>G (p.Cys998X) Mutation in the CEP290 Gene

The purpose of this double-masked, randomized, placebo-controlled, paired-eye study is to evaluate the efficacy, safety and tolerability of Sepofarsen in subje…

Leber Congenital Amaurosis 10BlindnessLeber Congenital Amaurosis+7 more

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Laboratoires TheaNCT06891443

Phase 3

A Randomized Phase III Trial of Carboplatin, Paclitaxel, Pembrolizumab Versus Carboplatin, Paclitaxel, Bevacizumab Versus Carboplatin, Paclitaxel, Pembrolizumab, Bevacizumab in the Treatment of pMMR, TP53 Mutated Advanced or Recurrent Endometrial Cancer

This phase III trial compares the effect of bevacizumab in combination with carboplatin, paclitaxel and pembrolizumab to the usual treatments of carboplatin an…

Advanced Endometrial CarcinomaRecurrent Endometrial Carcinoma

Estimated

~$50 – $1,350

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT07198074

Phase 2

A Single-Arm, Phase 2 Study of Neoadjuvant Carboplatin and Mirvetuximab Soravtansine in Subjects With FRα-Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. The purpose of this study is to assess the safety and efficacy …

Epithelial Ovarian CancerFallopian Tube CancerPrimary Peritoneal Cancer+1 more

Estimated

~$75 – $3,000

Actual pay is set by the research site.

AbbVieNCT06890338

Observational

Exploration of Tolerability and Dose Responses for a Yeast-based Probiotic

The purpose of this study is to evaluate the tolerability and efficacy of a yeast-based dietary supplement on gastrointestinal, mental, and skin health. Yeasts…

Healthy Adult ParticipantsGut Health

Estimated

~$10 – $750

Actual pay is set by the research site.

Colorado State UniversityNCT07867496

Phase 2

Cancer Lipidome Adaptation and Resculping Through Omega-3 PUFAs in Breast Tumors (CLARA)

This is a single-arm Phase 2 interventional treatment study to investigate changes in tissue lipidomes with omega-3 polyunsaturated fatty acids (PUFA) suppleme…

Breast Cancer

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Medical College of WisconsinNCT07643428

Phase 1

A Phase 1, Randomized, Single-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Ascending Doses of Orally Administered LY5625575 in Healthy Participants, Including Japanese and Chinese Populations, and in Participants With Elevated C-Reactive Protein

The main purpose of this study is to evaluate the safety and tolerability of LY5625575 in healthy participants (including Japanese and Chinese) and in particip…

Healthy VolunteersC-Reactive Protein

Estimated

~$500 – $11,250

Actual pay is set by the research site.

Eli Lilly and CompanyNCT07801300

Observational

Novel Post-Surgical Incision Management to Prevent Ostomy Complications

The goal of this clinical trial is to evaluate the safety and effectiveness of the Limpet, as compared to standard of care ostomy pouches, in reducing complica…

OstomyEnterocutaneous Fistula

Estimated

~$10 – $1,125

Actual pay is set by the research site.

HealthPartners InstituteNCT06524401