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A Randomized Placebo-procedure Controlled Trial of the Multi-Pole Pulmonary Artery Radiofrequency Ablation Enhancor System PULmonary Artery Denervation Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease

The goal of this clinical study is to evaluate the safety and efficacy of percutaneous pulmonary artery denervation with the Multi-Pole Pulmonary Artery Radiof…

Pulmonary HypertensionHeart Failure With Reduced Ejection FractionHypertension+5 more

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Pulnovo Medical, Inc.NCT07214376

Phase 1

Virtual Reality and Biofeedback for Adolescents With Chronic Dizziness

Both persistent postural-perceptual dizziness (PPPD) and vestibular migraine (VM) are common diagnoses in patients presenting to physicians for evaluation of v…

Persistent Postural Perceptual DizzinessVestibular MigraineChronic Dizziness

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Boston Children's HospitalNCT07374640

Phase 2

A Phase 2/3 Multicenter, Open-label, Randomized, Active-Control Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (waveLINE-003)

The purpose of this Phase 2/3, randomized, multisite, open-label, dose confirmation, and expansion study is to evaluate the safety, and efficacy of zilovertama…

DLBCLDiffuse Large B-Cell Lymphoma

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Merck Sharp & Dohme LLCNCT05139017

Observational

Geriatric Assessment and Management for Older Adults Undergoing Radiation Therapy for Head and Neck Cancer and Their Family Caregivers

This clinical trial compares the effect of geriatric assessment (GA)-based management of supportive care to usual care in treating older patients undergoing ch…

Localized Head and Neck Carcinoma

Estimated

~$10 – $750

Actual pay is set by the research site.

City of Hope Medical CenterNCT07225855

Phase 1

A Phase 1, First-in-Human Study of the Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Participants With Prostate Cancer

There are many treatment options for men with various stages of prostate cancer. Some treatments work well for a while but can cause medical problems in some m…

Hormone-refractory Prostate Cancer

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Astellas Pharma Global Development, Inc.NCT05997615

Phase 2

Aquamin® for Prevention of Ulcerative Colitis J-Pouch-associate Intestinal Inflammation

Ulcerative colitis (UC) is a disease that causes long-term inflammation in the digestive tract, and many people with this condition require surgery to remove t…

Ulcerative ColitisIleal Pouch

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Muhammad N Aslam, MDNCT07501078

Phase 2

An Open-label, Randomized, Multi-Center Study to Evaluate the Efficacy and Safety of Induction Treatment With Melphalan/HDS Followed by Consolidation Treatment With Trifluridine-Tipiracil Plus Bevacizumab Versus Trifluridine-Tipiracil Plus Bevacizumab Alone in Patients With Refractory Metastatic Colorectal Cancer With Liver Dominant Disease

The goal of this clinical trial is to learn if using a liver-directed therapy with high dose chemotherapy followed by approved cancer treatment to treat patien…

Refractory Metastatic Colorectal Cancer

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Delcath Systems Inc.NCT06607458

Phase 2

A Phase II Study of Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed or Refractory CD10-Negative Diffuse Large B-Cell Lymphoma (DLBCL) and High-Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements (HGBCL-DH-BCL2)

This phase II trial tests how well venetoclax, ibrutinib, prednisone, obinutuzumab, and Revlimid® (ViPOR) works in treating patients with CD10 negative diffuse…

High Grade B-Cell Lymphoma With MYC and BCL6 RearrangementsRecurrent Diffuse Large B-Cell LymphomaRecurrent Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type+12 more

Estimated

Observational

Development of a Recovery-Oriented Suicide Prevention Intervention With Peers for Clinical High Risk for Psychosis

Young people at clinical high risk for psychosis are more likely to experience suicide thoughts than the general population, but there are few suicide preventi…

Clinical High Risk for Psychosis (CHR)Suicidal IdeationPsychosis+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of California, San DiegoNCT07756567

Observational

Increasing Live Donor Kidney Transplantation Through Video-based Education and Mobile Communication

The study is a 2-arm randomized controlled trial among patients referred for kidney transplant evaluation at a single transplant center to compare the effects …

End-Stage Renal DiseaseChronic Kidney DiseasesKidney Transplant+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

State University of New York at BuffaloNCT07072767

Phase 3

A Phase 3, Multi-Center Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Risankizumab With Open-Label Induction, Randomized Double-Blind Maintenance, and Long-Term Extension Periods in Pediatric Subjects (2 to < 18 Years of Age) With Moderately to Severely Active Crohn's Disease

Crohn's Disease (CD) is a gastrointestinal disease that can cause chronic diarrhea with or without gross bleeding, abdominal pain, weight loss, and fever. This…

Crohn's Disease

Estimated

~$50 – $2,250

Actual pay is set by the research site.

AbbVieNCT05995353

Phase 1

A Pilot Trial of Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Sickle Cell Disease

A promising approach for the treatment of genetic diseases is called gene therapy. Gene therapy is a relatively new field of medicine that uses genetic materia…

Sickle Cell DiseaseSickle Cell Anemia (HbSS, or HbSβ-thalassemia0)

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Daniel BauerNCT07708350