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27,375 recruiting studies available now

SJ901: Phase 1/2 Evaluation of Single Agent Mirdametinib (PD-0325901), a Brain-Penetrant MEK1/2 Inhibitor, for the Treatment of Children, Adolescents, and Young Adults With Low-Grade Glioma

This is an open-label, multi-center, Phase 1/2 study of the brain-penetrant MEK inhibitor, mirdametinib (PD-0325901), in patients with pediatric low-grade glio…

Low-Grade GliomaRecurrent Low-Grade GliomaProgressive Low-Grade Glioma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

St. Jude Children's Research HospitalNCT04923126

Observational

Evaluation of the Epione Robotic System for Image-guided Percutaneous MSK Procedures of the Pelvis and Spine in USA. A Prospective Study on Feasibility, Safety and Accuracy

The goal of this investigational device exemption is to evaluate the Epione assistance for introducer placement during percutaneous procedures in musculo-skele…

Bone TumorOsteoporosisTraumatic Fracture

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Precision IO GroupNCT07325578

Observational

Testing Delivery Modalities of Team-Based Cognitive Behavioral Treatment (CBT) for Pediatric Anxiety in Community Health Settings: Developing Pathways to Health Equity

The purpose of this study is to test how the delivery of Cognitive Behavioral Therapy (CBT) for pediatric anxiety and OCD via different methods might increase …

Obsessive Compulsive Disorder (OCD)Pediatric Anxiety DisordersAnxiety Disorder+12 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Bradley HospitalNCT06934525

Phase 3

A Phase 3, Multicenter, Randomized, Double-Blinded, Placebo-Controlled Study to Evaluate the Safety and Efficacy of L606 (Treprostinil Liposome Inhalation Suspension) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (WHO Group 3)

The purpose of this study is to find out if L606 is safe and if it helps people with high blood pressure in the lungs (pulmonary hypertension) caused by inters…

Pulmonary Hypertension Due to Lung Disease (Disorder)

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Liquidia Technologies, Inc.NCT07285655

Phase 2

Alternating Treatment Plans for Participants With Advanced Thoracic/Head & Neck Cancers (ATATcH)

The purpose of the research is to evaluate a new schedule of alternating cycles of induction chemoimmunotherapy (chemotherapy plus pembrolizumab) and immunothe…

Head and Neck CancerLung Cancer

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Rutgers, The State University of New JerseyNCT05358548

The DETECT Study - Discovery and Evaluation of Testing for Endometrial and Ovarian Cancer in Tampons: Tampon and Tissue Sampling to Evaluate Markers for Detection of Endometrial and Ovarian Cancer

BACKGROUND: Endometrial cancer is a common and deadly cancer for women. It is getting more common and deadly because risk factors like age and obesity are inc…

Endometrial CancerEndometrial Cancer PrecursorsOvarian Cancer+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Alabama at BirminghamNCT03538665

Phase 1

A Phase I Study of DS-8201a in Combination With Olaparib in HER2-Expressing Malignancies

This phase I trial identifies the side effects and best dose of DS-8201a and olaparib in treating patients with HER2-expressing cancers that have spread to oth…

Metastatic Malignant Solid NeoplasmPlatinum-Resistant Ovarian High Grade Serous AdenocarcinomaUnresectable Malignant Solid Neoplasm

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT04585958

Observational

Virtual Group Resilient Living Program For Patients Living With Advanced Cancer

This study is a prospective, minimal risk, non-randomized, single-arm study to determine feasibility and assess effectiveness of a Virtual Group Resilient Livi…

Advanced Cancer

Estimated

~$10 – $750

Actual pay is set by the research site.

Mayo ClinicNCT07659158

Phase 4

Rimegepant as Preemptive Treatment for Predictable Trigger-Induced Migraine in Adult Patients in the US

Single-center, open label, prospective study conducted at Medstar Georgetown Headache Center. Men and woman ≥ 18 years old that are diagnosed with migraine wit…

MigraineTrigger Induced Migraine

Estimated

~$25 – $1,500

Actual pay is set by the research site.

Medstar Health Research InstituteNCT07301008

Phase 3

Type 1 Diabetes Impacts of Semaglutide on Cardiovascular Outcomes

This trial plans to learn more about the effects of a medication, semaglutide, on cardiovascular function, kidney function, and insulin sensitivity in adults w…

Diabetes Mellitus, Type 1

Estimated

~$50 – $1,500

Actual pay is set by the research site.

University of Colorado, DenverNCT05819138

Phase 2

Targeting Immune Modulation in High Grade Serous Carcinoma: Combined Effects of Chemotherapy and Atorvastatin

The goal of this clinical trial is to learn how atorvastatin in patients with advanced high grade serous cancer of the ovary, fallopian tube, or peritoneum cha…

Ovarian CancerFallopian Tube CancersPrimary Peritoneal Cancer+1 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of Colorado, DenverNCT07815704

Observational

A Feasibility Study of Using the CiniMacs® Device for Alpha/Best T-Cell Depletion in Stem Cell Transplant Recipients

Patients in need of an allogeneic hematopoietic cell transplant (HCT) are at risk of developing graft-versus-host-disease (GVHD). In certain clinical situation…

Graft Vs Host DiseaseGraft-versus-host-disease

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Christopher DvorakNCT04337515