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A PHASE 1, OPEN-LABEL, SINGLE-DOSE, PARALLEL-COHORT STUDY TO EVALUATE THE PHARMACOKINETICS, SAFETY, AND TOLERABILITY OF PF-07328948 IN ADULTS WITH AND WITHOUT VARYING DEGREES OF HEPATIC IMPAIRMENT

The purpose of this study is to understand the effects of decreased liver function on the study medicine (PF-07328948). People with decreased liver function ma…

Hepatic ImpairmentHealthy

Estimated

~$500 – $11,250

Actual pay is set by the research site.

PfizerNCT07269301

Observational

Cerebellar Transcranial Magnetic Stimulation and Cognitive Control

The purpose of this study is to examine whether cerebellar stimulation can be used to improve cognitive deficits and mood in patients with schizophrenia, autis…

SchizophreniaAutism Spectrum DisorderBipolar Disorder+2 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Krystal Parker, PhDNCT03217110

Phase 1

Phase 1/2 First-in-Human Study to Evaluate the Safety, Tolerability, and Efficacy of MZ-1866, an AAV-9 Gene Therapy Delivered by Intracerebroventricular Injection to Participants With Pitt Hopkins Syndrome

The goal of this clinical trial is to learn if MZ-1866 is a safe and tolerable treatment for children and adults with Pitt Hopkins Syndrome. To evaluate the s…

Pitt Hopkins Syndrome

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Mahzi TherapeuticsNCT07135050

Phase 1

Hyperpolarized Xenon-129 MRI in Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis has a poor prognosis with limited treatment options. The Investigator hypothesize hyperpolarized Xe129-MRI can be performed in pa…

Idiopathic Pulmonary Fibrosis

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of VirginiaNCT06853145

Phase 2

Electronic Nose (E-nose) Technology to Assess Pathologic Response and Post- Treatment Progression for Non-small Cell Lung Cancer: a Phase II Study

The researchers are doing this study to test the ability of a new technology called breathprinting, or electronic nose (E-Nose), to measure changes in certain …

Non-Small Cell Lung Cancer

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Memorial Sloan Kettering Cancer CenterNCT07218601

Phase 1

Phase 1 Clinical Trial of Lenvatinib, Pembrolizumab and Hypofractionated Pelvic Radiation Therapy for Mismatch Repair Proficient (pMMR) Recurrent/Unresectable Endometrial Carcinoma

The purpose of this research study is to see if it is feasible to combine a fixed dose of pembrolizumab and a daily dose of oral lenvatinib, along with daily t…

Recurrent Endometrial CarcinomaUnresectable Endometrial Carcinoma

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Aaron WolfsonNCT05603910

Phase 3

A Phase 3b/4, Multicenter, Parallel-Group, Double-Blind, Placebo Controlled, Two-Arm, Long-Term Study to Evaluate the Safety and Efficacy of Saroglitazar Magnesium on Clinical Outcomes in Participants With Primary Biliary Cholangitis (PBC)

Long-Term Study to Evaluate the Safety and Efficacy in Participants with Primary Biliary Cholangitis of Saroglitazar Magnesium-V on Clinical Outcomes (EPICS-V)

Primary Biliary Cholangitis

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Zydus Therapeutics Inc.NCT07216235

Target Trial Emulation for Pharmacologic Treatment of Neonatal Opioid Withdrawal Syndrome

The goal of this observational study is to learn how two medicines used in routine care-buprenorphine and morphine-affect recovery in newborns (≥36 weeks' gest…

Neonatal Opioid Withdrawal Syndrome

Estimated

~$10 – $1,125

Actual pay is set by the research site.

HELP for NOWS ConsortiumNCT07278375

Phase 4

Effect of Albumin Versus Routine Care on Hemodynamic Response and Stability in Patients With Preeclampsia Guided by a Non-invasive Hemodynamic Monitoring System During Cesarean Delivery With Spinal Anesthesia - A Randomized Controlled Study

The purpose of this study is to compare the effect of albumin versus routine care on hemodynamic response and stability in pre-eclamptic patients during cesare…

Pre-Eclampsia

Estimated

~$25 – $1,000

Actual pay is set by the research site.

The University of Texas Health Science Center, HoustonNCT06107335

Observational

MSK Injury Assessment Imaging System: Feasibility and Data Acquisition for Algorithm Development and Testing

The Accuro XV is a cart-based, bedside ultrasound instrument that incorporates new signal processing-based technologies for enhanced bone and soft-tissue imagi…

Fracture ArmFracture LegWrist Injury+1 more

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Rivanna Medical, Inc.NCT07853768

Observational

Diabetes Endothelial Keratoplasty Study (DEKS): Impact of Diabetes and Other Predictors on Corneal Transplant Endothelial Cell Loss and Success

This multi-center clinical trial is designed to assess the association of diabetes in a cornea donor with transplant success and loss of endothelial cells 5 ye…

Fuchs Endothelial Corneal DystrophyCorneal Endothelial Decompensation

Estimated

~$10 – $750

Actual pay is set by the research site.

Case Western Reserve UniversityNCT07217249

Expanding Access to Cognitive Health Biomarker Testing at Home

The goal of this observational study is to learn whether at-home blood biomarker testing for Alzheimer's disease risk is feasible and acceptable in older adult…

Mild Cognitive Impairment (MCI)Alzheimer's Dementia (AD)Subjective Cognitive Decline (SCD)+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of VirginiaNCT07594665