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Biologic Augmentation of Temporomandibular Joint Arthroscopy Using Bone Marrow Aspirate Concentrate (BMAC): A Proposed Clinical Trial

The goal of this clinical trial is to learn about the efficacy of using Bone Marrow Aspirate Concentrate (BMAC) during temporomandibular joint (TMJ) arthroscop…

TMJ - Oral &Maxillofacial SurgeryOral and Maxillofacial ConditionsTMJ Pain+1 more

Estimated

~$50 – $1,500

Actual pay is set by the research site.

Weill Medical College of Cornell UniversityNCT07536399

Phase 2

A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of V940 in Combination With Pembrolizumab and Chemotherapy as First-Line Treatment for Participants With Metastatic Squamous NSCLC (INTerpath-013)

Researchers want to know if intismeran autogene (the study treatment) given with pembrolizumab and chemotherapy can treat metastatic treatment-naive squamous n…

Squamous Non-small Cell Lung Cancer

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Merck Sharp & Dohme LLCNCT07221474

Phase 4

Vitamin K Reversal of INR for Perioperative Management of Warfarin: : A Pilot Study to Assess Feasibility

This is a feasibility study of uninterrupted warfarin with a one time dose of Vitamin K before a surgical procedure.

Anticoagulant Therapy

Estimated

~$25 – $1,000

Actual pay is set by the research site.

University of MichiganNCT07515664

Phase 1

A Phase 1, Open-Label, Single-Dose, Parallel-Group Study to Evaluate the Pharmacokinetics of Casdatifan (AB521) in Participants With Moderate Hepatic Impairment Compared to Healthy Matched Participants

The purpose of the study is to compare the single dose PK of casdatifan between participants with moderate hepatic impairment (HI) and healthy matched control …

Healthy ParticipantsHepatic Impairment

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Arcus Biosciences, Inc.NCT07751250

Phase 2

Multicenter, Randomized, Open-label, Active-controlled Study With a Blinded Assessor to Evaluate the Safety and Tolerability of Pivmecillinam Hydrochloride Versus Nitrofurantoin for the Treatment of Female Pediatric Subjects, 12 Years to Less Than 18 Years of Age, With Uncomplicated Urinary Tract Infections

Multicenter, Randomized, Open-label, Active-controlled Study with Blinded Assessor to Evaluate the Safety and Tolerability of Pivmecillinam Hydrochloride versu…

Uncomplicated Urinary Tract Infections

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Alembic TherapeuticsNCT07871968

Phase 1

A Phase I, Open-Label, Randomized, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Efficacy of XNW28012 Monotherapy in the Treatment of Subjects With Metastatic Pancreatic Cancer

A Phase I, Open-Label, Randomized, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Efficacy of XNW28012 Monotherapy in …

Metastatic Pancreatic Cancer

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Evopoint Biosciences Inc.NCT07707674

Observational

VA Quality Improvement Research and Training Initiative

The goal of this wait-list control trial is to learn if having access to a new dashboard displaying information about immunosuppressed Veterans missing vaccina…

Immunosuppresion

Estimated

~$10 – $675

Actual pay is set by the research site.

University of California, San FranciscoNCT06596148

Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery (MIS)

Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients treated with minimally invasive ap…

Adult Spinal DeformityScoliosisKyphosis+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

International Spine Study Group FoundationNCT04885244

Phase 1

The Effects of NTX-2001, a Novel TAAR1 Partial Agonist, on Alcohol Consumption in Adults With Alcohol Use Disorder: A Phase 1b, Randomized, Placebo-Controlled, Proof-of-Concept Study

The primary goal of this Phase 1b clinical trial is to evaluate the effects of a novel TAAR1 receptor partial agonist (NTX-2001) in adults with Alcohol Use Dis…

Alcohol Use Disorder

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Newleos Therapeutics, Inc.NCT07520292

Phase 2

Academic-Industrial Partnership for Translation of Acoustic Angiography: Contrast Enhanced Super Resolution (CESR) Imaging

This is a 4-arm, single-center study involving 40 participants. Ten healthy volunteers will be enrolled for system imaging optimization, and thirty (30) patien…

Breast CancerKidney NeoplasmsLiver Neoplasms

Estimated

~$75 – $2,000

Actual pay is set by the research site.

UNC Lineberger Comprehensive Cancer CenterNCT07225114

Observational

Feasibility of Flash-Sole in Human Trials: An Active Midsole Powered by Stacked Dielectric Elastomer Actuators for Push-Off Assistance

The goal of this clinical trial is to test a new shoe device called Flash-Sole. The Flash-Sole is designed to help support the ankle while walking. It was deve…

Motor Function

Estimated

~$10 – $750

Actual pay is set by the research site.

University of NebraskaNCT07507006

Phase 1

A Single Arm, Open-label Phase Ib/II Study of Asciminib in HER2+ Breast Cancer Brain Metastases (ASCENdANT)

The purpose of this study is to evaluate the intracranial response rate of a combination of asciminib/trastuzumab for the treatment of patients with metastatic…

HER2+ Metastatic Breast Cancer

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Duke UniversityNCT07136428