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A Phase 2b/Phase 3, Randomized, Double-blind, Placebo-controlled, Multicenter Study, to Investigate the Efficacy and Safety of Lunsekimig in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype

This is a parallel, Phase 2b/Phase 3, 3-arm study to investigate the efficacy, safety, and tolerability of subcutaneous (SC) treatment with lunsekimig compared…

Chronic Obstructive Pulmonary Disease

Estimated

~$50 – $2,250

Actual pay is set by the research site.

SanofiNCT07190222

Use of Noninvasive Wearables Biomonitoring to Detect Pre-Smoking, Smoking, And Post-Smoking Stages: An Observational Laboratory Study

Background: It is important to quickly identify when people are at risk of smoking. Most current methods rely on people reporting when they smoke or what makes…

Smoking

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute on Minority Health and Health Disparities (NIMHD)NCT07067151

Observational

A Prospective Study to Evaluate the Use of the Minder Device to Aid in Developing a Treatment Plan After Inconclusive Prolonged EEG in Patients With Epilepsy

The purpose of this research is to address the challenges of diagnosing and long-term management of epilepsy in participants whose seizures are not well captur…

EpilepsyEpilepsy (Treatment Refractory)

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Epiminder America, Inc.NCT07110337

Phase 2

A Pilot Study in the Treatment of Refractory Epstein-Barr Virus (EBV) Infection With Related Donor EBV Cytotoxic T-Lymphocytes in Children, Adolescents and Young Adult Recipients

Related donor Epstein-Barr Virus (EBV) specific cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be admin…

Epstein-Barr Virus InfectionsPrimary Immune Deficiency Disorder

Estimated

~$75 – $2,000

Actual pay is set by the research site.

New York Medical CollegeNCT03266653

Phase 2

A Phase 2a Randomized, Double-Blind Study to Evaluate the Safety, Biomarker Activity, and Microglial Activation of Nasal Foralumab in Patients With Amyotrophic Lateral Sclerosis (ALS)

The goal of this clinical trial is to learn whether a nasal spray medicine called foralumab is safe and easy to tolerate in adults with amyotrophic lateral scl…

ALS (Amyotrophic Lateral Sclerosis)ALS - Amyotrophic Lateral SclerosisALS

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Tiziana Life Sciences LTDNCT07688239

Phase 1

A Phase 1 Trial to Evaluate the Safety of IL13Rα2-Targeting Chimeric Antigen Receptor (CAR) T Cells With CRISPR Knockout of TGFβR2 in Patients With Recurrent or Progressive High-Grade Glioma (HGG)

This phase I trial tests the safety, side effects and best dose of TGFβR2KO/IL13Rα2 chimeric antigen receptor (CAR) T-cells given within the skull (intracrania…

Recurrent Astrocytoma, IDH-Mutant, Grade 3Recurrent Astrocytoma, IDH-Mutant, Grade 4Recurrent Glioblastoma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

City of Hope Medical CenterNCT06815029

Observational

Is Splinting After Ulnar Nerve Transposition Necessary?

The goal of this clinical trial is to learn whether patient recovery after ulnar nerve transposition (UNT) requires a splint. The main questions it aims to ans…

Ulnar Nerve Transposition

Estimated

~$10 – $750

Actual pay is set by the research site.

University of ChicagoNCT07880470

International Ovarian & Testicular Stromal Tumor Registry

Rare tumors are understudied, yet have the potential to shed light on vast areas of cancer research. Ovarian sex cord-stromal tumors, rare tumors of childhood …

Ovarian Sex-cord Stromal TumorTesticular Stromal TumorsOvarian Small Cell Carcinoma

Estimated

~$10 – $750

Actual pay is set by the research site.

Children's Hospitals and Clinics of MinnesotaNCT01970696

Phase 2

A Phase 2a Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-8690 in Adult Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this protocol is to evaluate the efficacy of MK-8690 in participants with moderately to severely active ulcerative colitis. The primary hypothes…

Colitis UlcerativeUlcerative Colitis

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Merck Sharp & Dohme LLCNCT07463183

Phase 1

Clinical Trial of D2C7-IT + 2141-V11 Combination Immunotherapy Administered Via Convection Enhanced Delivery in Non-enhancing Tumor Post-resection of Recurrent Glioblastoma, Followed by Cervical Perilymphatic Subcutaneous Injections of 2141-V11

The purpose of this study is to assess the safety and efficacy of the combination of D2C7-IT+2141-V11 administered in the non-enhancing tumor of patients with …

Recurrent Glioblastoma IDH Wildtype

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Darell BignerNCT06455605

Phase 1

Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder

The goal of this clinical trial is to learn if a single dose of psilocybin (5mg Vs 10mg Vs 25mg) alongside psychotherapy is safe and can help treat treatment r…

Treatment Resistant DepressionSubstance Use Disorders

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Indiana UniversityNCT07499583

Observational

Using Community Health Workers to Support Rural Care Partners of Seriously Ill Older Veterans

The investigators aim to support care partner's well-being and satisfaction with VA care and decrease their work burden by offering extra support from a traine…

DementiaCancerRenal Disease+1 more

Estimated

~$10 – $675

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT06963970