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27,306 recruiting studies available now

A Phase 1, Randomized, Double-Blind, Placebo-Controlled, First-in-Human Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single Ascending Doses of Orally Administered BMS-986485 in Healthy Adult Participants (Part A), and a Conditional Open-label Study to Evaluate the Relative Bioavailability of Alternate Formulations of BMS-986485 in Healthy Adult Participants (Part B)

The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of the administration of a single ascending doses of BMS-986485 in heal…

Healthy Volunteers

Estimated

~$500 – $11,250

Actual pay is set by the research site.

Bristol-Myers SquibbNCT07887763

Pioneering Research to Optimize Pre-exposure Prophylaxis (PrEP) Expansion With Lenacapavir (LEN)

The goal of this observational study is to generate real-life information on the use of lenacapavir (LEN, YEZTUGO®, (YTG)) for pre-exposure prophylaxis (PrEP) …

HIV Infections

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Gilead SciencesNCT07473778

Phase 3

A Phase 3 Multicenter, Randomized, Double-Blind, Placebo Controlled Trial to Evaluate Efficacy and Safety of Mezagitamab (TAK-079) in Study Participants With Primary IgA Nephropathy in Combination With Stable Background Therapy

Immunoglobulin A nephropathy (IgAN) is a kidney condition. It happens when the body's immune system creates groups of proteins (called immune complexes) that b…

Kidney Disease

Estimated

~$50 – $2,250

Actual pay is set by the research site.

TakedaNCT06963827

Community-Based Intensive Treatment (CBIT): Meeting the Complex Needs of Rural Adults With Serious Mental Illness Post-Psychiatric Hospitalization

The purpose for this research project is to successfully achieve the primary systems intervention outcome, maintaining fidelity to the intervention model and t…

Severe Mental IllnessHospitalizations PsychiatricRural Healthcare-seeking Behaviour+4 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Yale UniversityNCT07887113

Observational

Applying a Family Caregiver Supports Needs Assessment Tool in Home-based Primary Care: An Approach to Elder Mistreatment Risk Reduction and Prevention

This study will evaluate the feasibility, acceptability, and preliminary effects of the Carer Support Needs Assessment Tool (CSNAT) intervention for family car…

Caregiver StressCaregiver Health Related QOLCaregiver Mental Health+3 more

Estimated

~$10 – $750

Actual pay is set by the research site.

The University of Texas Medical Branch, GalvestonNCT07749482

Phase 3

A Phase 3, Randomized, Double-blind, Active-control Study of Pelabresib (DAK539) and Ruxolitinib vs. Placebo and Ruxolitinib in Adult Patients With Myelofibrosis Who Are JAK Inhibitor Naive

The purpose of this trial is to evaluate whether treatment with pelabresib in combination with ruxolitinib leads to improved clinical outcomes compared to ruxo…

Primary Myelofibrosis (PMF)Post-polycythemia Vera Myelofibrosis (PPV-MF)Post-essential Thrombocythemia Myelofibrosis (PET-MF)

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Novartis PharmaceuticalsNCT07357727

Observational

Temporal Nature of Cognitive and Visuospatial Brain Domain Changes During Long-Duration Low-Earth Orbit Missions (Spatial Cognition)

This study investigates the effects of extended-duration spaceflight (12-month International Space Station missions) on general cognitive performance (measured…

Brain StructureCognitive Performance

Estimated

~$10 – $750

Actual pay is set by the research site.

University of PennsylvaniaNCT04856410

Clinical Study Protocol SGi 1.0 + EPW 1.0 + Compatible Clinical Displays Clinical Validation Study

The primary objective of this study is to show safety and effectiveness of the investigational device for In Vitro Diagnostic (IVD) use as an aid to the pathol…

Pathological Processes

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Philips Digital & Computational PathologyNCT07881874

Observational

Plasma Lipids-dependent Vitamin E Metabolism During Dynamic Hyperlipidemia

Background: Obesity is known to lead to diseases such as diabetes and high cholesterol (or fats) in the blood (hyperlipidemia). But no one knows why. Research…

Lipid Metabolism Disorders

Estimated

~$10 – $675

Actual pay is set by the research site.

National Heart, Lung, and Blood Institute (NHLBI)NCT07715890

The Natural History of Acquired and Inherited Bone Marrow Failure Syndromes

Background: Bone marrow failure diseases are rare. Much is known about the diseases at the time of diagnosis, but long-term data about the effects of the dise…

Severe Aplastic AnemiaTelomere Biology DisordersInherited Bone Marrow Failure Syndromes

Estimated

~$10 – $675

Actual pay is set by the research site.

National Heart, Lung, and Blood Institute (NHLBI)NCT05012111

Phase 2

A Randomized Phase II Trial of Nivolumab and Ipilimumab Compared to Nivolumab Monotherapy in Patients With Deficient Mismatch Repair System Recurrent Endometrial Carcinoma

This phase II trial tests whether the combination of nivolumab and ipilimumab is better than nivolumab alone to shrink tumors in patients with deficient mismat…

Endometrial AdenocarcinomaEndometrial Clear Cell AdenocarcinomaEndometrial Dedifferentiated Carcinoma+6 more

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)

Magnetic Resonance Elastography as a Method to Estimate Stiffness of Soft Tissues

Magnetic resonance elastography is a novel non-invasive MRI technique to obtain stiffness of soft tissues such as liver, heart, kidneys, etc. In this imaging t…

Heart FailureLiver FibrosisCardiac Transplant Rejection+1 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Arunark KolipakaNCT01757730