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A Phase I Study to Assess Safety and Feasibility of IL-8 Receptor Modified Patient-Derived Activated CD70 CAR T Cell Therapy in Adults With Brain Metastases From Primary Cancers (IMPACT-MET)

This is a Phase I Study evaluating the safety and feasibility of IL-8 receptor-modified patient-derived activated CD70 CAR T cells in adult patients with brain…

Brain Metastases

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of FloridaNCT07569263

Biology of Juvenile Myoclonic Epilepsy

The investigators are collecting genetic information through blood samples as well as clinical and EEG data from over 1000 people with Juvenile Myoclonic Epile…

Juvenile Myoclonic Epilepsy

Estimated

~$10 – $750

Actual pay is set by the research site.

King's College LondonNCT03400371

Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia (HSP)

The Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia (HSP) is focused on gathering longitudinal clinical data as well as biolog…

Hereditary Spastic ParaplegiaSPG47SPG50+8 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Boston Children's HospitalNCT04712812

Using Ex Vivo Tumoroids To Predict Immunotherapy Response In NSCLC (TUMORIN)

To test whether it is feasible to perform the 3D-EX functional predictive response bioassay in the context of patients with advanced/metastatic NSCLC receiving…

Lung CancerNSCLCNSCLC Stage IV

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Jun Zhang, MD, PhDNCT05332925

Observational

Engaging Patients in Decision Making: The Development and Pilot Testing of a Low Literacy Spanish Language Shared Medical Decision Tool for Ovarian Cancer Maintenance Therapy

To develop a shared decision-making (SDM) tool to help Spanish-speaking patients make decisions about their maintenance therapy

Ovarian Cancer

Estimated

~$10 – $750

Actual pay is set by the research site.

M.D. Anderson Cancer CenterNCT06036810

Phase 1

Mitigation of Arthrofibrosis After Total Knee Arthroplasty Using Losartan

The purpose of this study is to evaluate the efficacy of Losartan use post-operatively for reducing or preventing the development of arthrofibrosis and the ass…

Knee Arthroplasty, Total

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Steadman Philippon Research InstituteNCT06108063

Observational

Education and Employment Support for HIV Prevention in Young Adults (ENSPIRE)

The study team will conduct a two-group study to examine the efficacy of implementing a combination intervention to improve economic stability and HIV preventi…

Economic HardshipCondomless SexUtilization, Health Care

Estimated

~$10 – $750

Actual pay is set by the research site.

University of North Carolina, Chapel HillNCT06096324

Phase 2

Brain Metastases in Greater Size - Hypofractionated Options Trial (BIGSHOT)

This is a randomized, phase II trial comparing staged stereotactic radiosurgery (SSRS) versus fractionated stereotactic radiotherapy (FSRT) in patients with la…

Brain MetastasesCancer (With CNS Involvement)

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Medical University of South CarolinaNCT07227610

Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With ACTIVE CONTROL System Performance

An observational, prospective multi-regional post-market registry collecting mid- and long-term data to assess outcomes through ten years of follow-up for subj…

Vascular DiseaseDissectionDissection Aortic Aneurysm+5 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

W.L.Gore & AssociatesNCT06658730

Kidney Precision Medicine Project

Acute kidney injury (AKI) and chronic kidney disease (CKD) impose a significant global health burden. Yet, no effective therapies currently exist for AKI, and …

Acute Kidney FailureAcute Kidney InsufficiencyAcute Renal Failure+12 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Icahn School of Medicine at Mount SinaiNCT04334707

Phase 3

Efficacy and Safety of NNC0487-0111 s.c. Once-weekly in Participants With Overweight or Obesity, and Obstructive Sleep Apnoea Treated With Positive Airway Pressure (AMAZE 4)

This study is being done to look at the efficacy and safety of NNC0487-0111 in participants with overweight or obesity, and obstructive sleep apnoea treated wi…

ObesityOverweightObstructive Sleep Apnoea

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Novo Nordisk A/SNCT07571109

Observational

Stories to Prevent (StoP) HPV Cancers: A Communication Intervention to Increase HPV Vaccination Among Diverse Populations.

This randomized controlled trial (RCT) evaluates the association of a narrative communication intervention on human papillomavirus (HPV) vaccination rates amon…

Human Papillomavirus VaccinationEmotions

Estimated

~$10 – $750

Actual pay is set by the research site.

Milton S. Hershey Medical CenterNCT06808776