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Prospective Validation of a Reduced-Montage TMS-EEG Complexity Algorithm (Presence-IP1.0) to Differentiate Conscious and Unconscious States Across Wakefulness and Sleep

This study aims to validate a novel real-time algorithm (Presence-IP1.0) designed to detect consciousness from TMS-evoked EEG responses using a reduced electro…

Sleep

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Wisconsin, MadisonNCT07523191

Observational

Improving Chronic Disease Outcomes Across the Lifespan by Addressing Structural Racism

The goal of this clinical trial is to learn if the implementation of the WE CARE social determinants of health (SDOH) screening and referral intervention with …

HyperlipidemiasDiabetesDepression+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Massachusetts, WorcesterNCT06903897

Breast Cancer-Minimal/Molecular Residual Disease Detection and Therapy Monitoring in Patients with Early Stage TNBC-Phase I (B-STRONGER-I)

A prospective, multicenter, observational study to evaluate the correlation of Molecular Residual Disease (MRD) detection using circulating tumor DNA guided te…

TNBC - Triple-Negative Breast CancerMinimal Residual Disease

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Personalis Inc.NCT06230185

Observational

Em-power: Maximizing Functional Independence for Children With Severe Cerebral Palsy

For children with severe cerebral palsy, a powered wheelchair (PWC) may provide their only option for functional mobility and independence. PWC use is often re…

Cerebral Palsy

Estimated

~$10 – $750

Actual pay is set by the research site.

Grand Valley State UniversityNCT06347432

Phase 4

Lumateperone Added to Antidepressant Therapy in Adults With Major Depressive Disorder Experiencing Emotional Blunting

The purpose of this study is to evaluate whether or not adding lumateparone to current antidepressant treatment in adults with major depressive disorder experi…

Blunted Emotion in Major Depressive Disorder

Estimated

~$25 – $1,400

Actual pay is set by the research site.

Future Options Research, LLCNCT07824206

Phase 3

A Phase 3, Multicenter, Double-Masked, Randomized, 3-Arm Parallel Group Study to Evaluate the Efficacy and Safety of Intravitreal OTXTKI (Axitinib Implant) in Participants With Non-Proliferative Diabetic Retinopathy

The purpose of this trial is to study the safety and effectiveness of OTX-TKI (axitinib intravitreal hydrogel) for the treatment of Non-Proliferative Diabetic …

Non-Proliferative Diabetic Retinopathy

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Ocular Therapeutix, Inc.NCT07235085

Phase 3

A PHASE 3, RANDOMIZED, DOUBLE-BLIND TRIAL TO EVALUATE THE SAFETY, TOLERABILITY, AND IMMUNOGENICITY OF 3 LOTS OF A MULTIVALENT PNEUMOCOCCAL CONJUGATE VACCINE IN ADULTS

The purpose of this study is to provide safety data and demonstrate lot consistency with the PG4 vaccine by evaluating the immunogenicity of 3 different lots o…

Pneumococcal Disease

Estimated

~$50 – $2,250

Actual pay is set by the research site.

PfizerNCT07794748

Parkinson's Foundation PD GENEration Genetic Registry

Development of a central repository for PD-related genomic data for future research.

Parkinson's Disease

Estimated

~$10 – $750

Actual pay is set by the research site.

Parkinson's FoundationNCT04994015

Phase 2

A Phase 2, Single-Arm Trial of Relacorilant in Combination With Nab-Paclitaxel and Gemcitabine in Chemotherapy-Naïve Patients With Metastatic Pancreatic Adenocarcinoma (TRIDENT)

This is a 2-part, Phase 2 study to evaluate the safety, tolerability, dosing, pharmacokinetics (PK), and efficacy of relacorilant in combination with nab-pacli…

AdenocarcinomaCarcinoma, Pancreatic Ductal

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Corcept TherapeuticsNCT07259317

Barriers And Facilitators To Clinical Trial Enrollment: A Qualitative Study Of Pancreatic Cancer Patients

The purpose of this research is to understand why some groups of people do not join clinical trials as much as others. These groups can include people from dif…

Pancreatic Cancer

Estimated

~$10 – $750

Actual pay is set by the research site.

M.D. Anderson Cancer CenterNCT07591480

Phase 3

Early Reinitiation of Semaglutide Post-Sleeve Gastrectomy in Youth: A Randomized Clinical Trial

This is a Phase 3a, randomized, parallel-controlled trial designed to compare the early re-initiation of semaglutide, starting two weeks after sleeve gastrecto…

Pediatric ObesityMetabolic and Bariatric SurgerySemaglutide

Estimated

~$50 – $1,500

Actual pay is set by the research site.

Children's Hospital Los AngelesNCT06934655

Phase 1

A Phase 1 Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of BGB-21447 (a Bcl-2 Inhibitor) Combinations for Patients With HR+/HER2- Metastatic Breast Cancer

This is a dose escalation and dose expansion study to assess the safety and tolerability of BGB-21447 (a B-cell leukemia/lymphoma 2 inhibitor, Bcl-2i) in combi…

Hormone-receptor-positive Breast CancerHER2-negative Breast CancerMetastatic Breast Cancer

Estimated

~$150 – $4,500

Actual pay is set by the research site.

BeOne MedicinesNCT06756932