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27,293 recruiting studies available now

A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Confirm Efficacy and Safety of MH002 and to Assess the Effect of Dose in Patients With Mild-to- Moderate Ulcerative Colitis Insufficiently Controlled With 5-Aminosalicylic Acid

The main goal of the study is to check if MH002 works and is safe to use. In a previous study in 45 patients with Ulcerative Colitis, MH002 was found to have f…

Colitis, Ulcerative

Estimated

~$75 – $3,000

Actual pay is set by the research site.

MRM Health NVNCT07296315

Observational

Robotic Systems Evaluation for Peripheral Pulmonary Lesions: A Randomized Trial (RISE Trial)

This is an investigator-initiated cluster randomized control trial. The primary objective is to compare the diagnostic yield of two Food and Drug Administratio…

Lung; Node

Estimated

~$10 – $750

Actual pay is set by the research site.

Case Comprehensive Cancer CenterNCT07735611

Phase 3

A Phase 3, Randomized, Double-Blind, Placebo-Controlled, 3-Arm, 3-Period Study to Assess the Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

The purpose of this clinical study is to determine the efficacy and safety of a new oral cladribine formulation in participants with Generalized Myasthenia Gra…

Generalized Myasthenia Gravis

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, GermanyNCT06463587

Phase 2

A Phase 2, Open-label Study of VS-7375, an Oral KRAS G12D (ON/OFF) Inhibitor, With and Without an Anti-EGFR Antibody, and With an Anti-EGFR Antibody and Chemotherapy, in Patients With Metastatic KRAS G12D-Mutated Colorectal Adenocarcinoma (TARGET-D 203)

This study will assess the safety and efficacy of VS-7375 alone and in combination with cetuximab or panitumumab and cetuximab plus mFOLFOX in patients with me…

Colorectal Cancer

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Verastem, Inc.NCT07659795

Phase 2

A Phase 2b, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Safety, Tolerability, and Efficacy of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus Who Are at High Risk of Progression to Severe Disease

The main purpose of this study is to investigate the antiviral effect of S-337395 compared with placebo among nonhospitalized adult participants with high-risk…

Respiratory Syncytial Virus Infections

Estimated

~$75 – $3,000

Actual pay is set by the research site.

ShionogiNCT07214571

Observational

Pericardiotomy in Cardiac Surgery Trial

PRINCE is an international, multicentre, randomized controlled trial of posterior pericardiotomy in patients without a history of atrial fibrillation (AF) or f…

Atrial FibrillationAtrial FlutterCardiac Events

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Population Health Research InstituteNCT06486636

Phase 1

Phase I Trial of Pacritinib in Combination With Venetoclax and Azacitidine for the Treatment of Accelerated and Blast Phase Myeloproliferative Neoplasms

This phase I trial studies the side effects and best dose of pacritinib when given together with venetoclax and azacitidine in treating patients with accelerat…

Myeloproliferative Neoplasm

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Roswell Park Cancer InstituteNCT07679334

Observational

The Effects of Heel Distraction Height on Foot Loading With Carbon Fiber Custom Dynamic Orthoses

Carbon fiber custom dynamic orthoses (CDOs) and unloading ankle foot orthoses (AFOs) have shown varying levels of success in reducing forces acting on differen…

Traumatic Lower Limb Injury

Estimated

~$10 – $750

Actual pay is set by the research site.

University of IowaNCT06127316

Observational

Sleep MAPP: A Tool to Improve Insomnia Disorder Treatment Among Veterans Receiving Polytrauma/TBI System of Care Services

This pilot implementation trial will evaluate the Sleep Disorder Management Assistance for Providers and Patients (Sleep MAPP) Care Pathway in one Veterans Hea…

Insomnia DisorderMild Traumatic Brain Injury

Estimated

~$10 – $675

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT07886398

Observational

Nonoperative vs. Surgical Release for Acute-to-Subacute Lateral Epicondylitis: A Prospective Randomized Controlled Trial

Tennis elbow is a condition that causes pain on the outside of the elbow, typically caused by motions involving straightening of the arm. The goal of this clin…

Lateral Epicondylitis

Estimated

~$10 – $750

Actual pay is set by the research site.

University of PittsburghNCT07885280

Phase 3

A Phase III, Randomised, Placebo-controlled, Event-driven Study to Evaluate the Effect of Baxdrostat in Combination With Dapagliflozin Compared With Dapagliflozin Alone on the Risk of Incident Heart Failure and Cardiovascular Death

Participants include men and women ≥ 40 years of age with T2DM, established CV disease, a history of HTN with an SBP of at least 130 mmHg at screening, who mee…

Heart Failure

Estimated

~$50 – $2,250

Actual pay is set by the research site.

AstraZenecaNCT06677060

Multi-center, Single-arm, Observational Study Assessing Real-world Safety and Performance of the TRIFORMIS RESILIA Tricuspid Valve for Surgical Tricuspid Valve Replacement (TRIBLAZE Study)

TRIBLAZE is a prospective, observational, single-arm, multicenter study designed to collect real-world clinical outcomes in a minimum of 75 participants who wi…

Heart Valve DiseasesHeart DiseasesCardiovascular Diseases+1 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Edwards LifesciencesNCT07684313