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Bipolar Androgen Therapy in Metastatic Castration-Resistant Prostate Cancer (mCRPC)
This phase I trial tests the change in androgen receptor sensitivity, side effects and effectiveness of bipolar androgen therapy, using testosterone, in patien…
The Effect of Intraoperative Cortical Stimulation on Hand Strength and Function During Awake Craniotomies
The neurosurgical standard of care for treating a patient with a tumor invading hand primary motor cortex (M1) includes performing a craniotomy with intraopera…
Preventive Reminder Ordering AssistanCe Via Texting for Improved Visit Encounters
A substantial portion of the United States population remains overdue for key screenings, despite availability and insurance coverage of preventive health serv…
The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU
The purpose of this study is to determine whether modifying the timing of nutrition support from overnight to daytime enhances sleep quality, preserves circadi…
Feasibility, Acceptability, and Preliminary Efficacy of an HIV Prevention Intervention for Older Black Women
The goal of this clinical trial is to learn whether a group-based HIV prevention program can improve HIV knowledge, prevention behaviors, and testing in older …
Defining Protein Requirements in Adults With PKU: Impact of Genotype and Medical Food Intake
The objective of this research is to determine the protein requirements based on genotype and medical food consumption in a sample of adults with Phenylketonur…
Effects of Transcranial Photobiomodulation and Attention Bias Modification on Anxiety Symptoms and Brain Hemodynamics
The investigators have previously shown that safe, non-invasive methods of brain stimulation such as the administration of transcranial infrared light can resu…
Resistant Starch Usage in Polycystic Ovary Syndrome: Impact on Cardiometabolic Dysfunction and the Gut Microbiome (CORS-PCOS)
This study will enroll women with PCOS to study the effects of first line therapy, oral contraceptive pills, and then either 12 weeks of resistant starch or 12…
Intravaginal Injection of Poly-L-Lactic Acid for Treatment of Cystocele: A Randomized Trial
Pelvic organ prolapse (POP) is a condition characterized by descent of vaginal walls, uterus and cervix, or the perineum and causes a sensation of vaginal bulg…
Improving Goals of Care Conversations With Hematopoietic Cell Transplant Survivors (IMPACT - HCT)
This clinical trial evaluates the impact of patient navigation and the Planning Advance Care Together (PACT) website, either alone or in combination with one a…
Open Versus Arthroscopic Stabilization of Shoulder Instability With Subcritical Bone Loss: The OASIS Trial
This clinical trial will determine the outcome trajectories of common surgeries (arthroscopic Bankart repair with remplissage of a Hill-Sachs lesion, open Bank…
Phase II Investigation of Pembrolizumab in Combination With Bevacizumab and Oral Cyclophosphamide in Patients With High Grade Ovarian Cancer and Surgically Documented Minimal Residual Disease After Frontline Therapy
To find out if combining pembrolizumab, bevacizumab (or an equivalent biosimilar drug), and low-dose cyclophosphamide can help control high-grade ovarian cance…