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Exercise Enhances Wound Healing in Patients With Diabetic Foot Ulcers
The overarching purpose of this study is to investigate the impact that exercise, as delivered through a medically supervised, outpatient cardiac rehabilitatio…
Studies of Human Inference Using On-line Testing
The investigators will record behavioral responses from human participants on crowdsourcing platform Prolific to identify the decision strategies humans apply …
Assessing Psyllium Given With Meals for Fructan Sensitivity in Children With Irritable Bowel Syndrome
The goal of this clinical trial is to learn if a fiber (psyllium) can change the way bacteria use fructans (a type of sugar) and whether psyllium can help decr…
Immediate Versus Delayed Loading of Maxillary Overdenture Implants
The purpose of the study is to evaluate the radiographic, clinical and patient-centered outcomes of implant-retained immediately-loaded maxillary complete dent…
Inhalation Approaches to Nausea: A Randomized Controlled Trial
The goal of this research study is to understand the effect of inhalation approaches in reducing nausea in cancer patients.
Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis Stress
The objectives of this study are to determine if the 'Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis Stres…
A Proof-of-Concept Open-Label Clinical Trial to Evaluate the Safety, Tolerability, and Efficacy of CSTI-500 in Participants With Prader-Willi Syndrome
This is a proof-of-concept, open-label, dose-escalation study to evaluate the safety, tolerability, pharmacokinetics, and efficacy of CSTI-500 in participants …
Improving Mediolateral Walking Balance With an Assistive Exoskeleton
Many people who have experienced a stroke have deficits in their walking balance. The long-term goal of this research is to develop an exoskeleton that can eff…
Testing the Efficacy of a New Intervention for High Intensity Drinking Among Emerging Adults
This study is being completed to test prevention methods to promote wellness and reduce risky behaviors, including the use of substances such as alcohol and ot…
NIEHS Repository of Stored Biological Samples for Future Use
Background: Laboratory tests that use blood and urine can provide a great deal of information about human health and disease. To develop even better tests and…
Effect of Inhaled Nitric Oxide on Major Adverse Events Requiring Intensive Life Support in Adults Undergoing Cardiac Surgery With Cardiopulmonary Bypass: A Phase III, Double-Blind, Multicenter, Randomized Controlled Trial (Nitric Oxide for Reduced Intensive Support in Cardiac Surgery With Cardiopulmonary Bypass, the NORISC Trial)
Cardiac surgery is a procedure that is commonly performed worldwide. Despite these technological advances, cardiac surgery remains a high-risk surgery. Among p…
Enhancing Treatment Outcomes Among Veterans With Alcohol Use Disorder: Clinical and Neural Markers of Adjunctive Approach-avoidance Training
The proposed study will test a novel treatment for alcohol use disorders (AUD) to determine if it helps Veterans reduce their hazardous drinking and recover fr…