Mayo Clinic
The investigators aim to learn more about symptoms suggestive of a neurodegenerative process.
The investigators will recruit participants with symptoms suggestive of a neurodegenerative and/or related disease. Participants could be evaluated on a yearly basis, undergoing a baseline visit and possible follow-up evaluations with an interval of one year. At each visit, participants could undergo any combination of the following based on their symptoms and complaints: a neurological assessment, a speech/language assessment, a neuropsychometric assessment, an MRI, an FDG PET/CT scan, a PiB PET/CT scan, a Tau PET/CT scan and/or a C-11 ER176 PET/CT scan. All participants will be asked to prov…
Inclusion Criteria: * All participants will be over the age of 21 * Have symptoms suggestive of a neurodegenerative and/or related disorder Exclusion Criteria: * Participants will be excluded if they have any concurrent illnesses that could account for all of their symptoms, such as traumatic brain injury, encephalitis, strokes or developmental syndromes * Women that are pregnant or post-partum and breast-feeding will be excluded * Participants will be excluded if they have any of the following genetic conditions which can increase the chance of cancer: Cowden disease, Lynch syndrome, Hypog…
Completing PET scan looking for amyloid protein
Completing PET scan looking for tau protein
Completing PET scan looking for neuroinflammation
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