Time Restricted Feeding Intervention for Muscle and Metabolic Health (TRIMM)
University of Arkansas, Fayetteville
Summary
Effective nutrition strategies for combatting and/or preventing obesity still need to be identified. This has been the case despite the numerous and different approaches that have been taken. Potential targets for combatting/preventing obesity have been identified, but long-term solutions have not emerged. This study uses time restricted feeding to study the role of dietary protein in obesity prevention and/or treatment. The objectives are to determine the role of skeletal muscle mass as a driver of energy-sensing mechanisms and peripheral signals that regulate appetite and energy intake in overweight and obese adults and to determine the effects of protein timing on muscle mass to regulate appetite and energy intake in overweight and obese adults.
Eligibility
- Age range
- 25–50 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Resides in Northwest Arkansas * Age 25-50 years * BMI \> 25 * All ethnicities * Female and male Exclusion Criteria: * Food allergies * Pregnant or breastfeeding * Dietary restrictions (e.g. vegetarian, vegan, etc.) * Trying to lose weight in last 3 months * Pre-existing health conditions related to obesity (e.g. cardiovascular disease, diabetes, hypertension) * Prescription medications related to heart disease or type 2 diabetes * Fear of needles * Smoker or vaping * Currently taking protein supplements or other nutritional supplements which may interfere with study ou…
Interventions
- Dietary SupplementWhey protein supplement
Participants consume whey protein at the beginning of the eating period.
- Dietary SupplementKetogenic aid
Participants consume ketogenic aid upon waking.
- OtherControl group - time restricted feeding only
Time restricted feeding.
Location
- University of ArkansasFayetteville, Arkansas