Cardiovascular Effects of a Healthy Dietary Pattern Containing Eggs: a Controlled-feeding Study
Penn State University
Summary
This study will examine the effect of a healthy diet containing 2 eggs per day compared to a healthy diet containing 3 eggs per week on biomarkers of heart health after 4 weeks.
Description
This is a 2-period, randomized, crossover, controlled feeding study examining the effect of 2020-2025 Dietary Guidelines for Americans adherent dietary patterns containing 2 eggs/day/2000 kcal (HD+E) compared to 3 eggs/week/2000 kcal (HD) on biomarkers of cardiovascular health and function after 4 weeks.
Eligibility
- Age range
- 30–60 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * LDL-C ≥115 mg/dL and ≤190 mg/L * BMI of 25-35 kg/m2 * Intake of \<14 eggs/week for the prior 3 months * Blood pressure \<140/90 mmHg * Fasting blood glucose \<126 mg/dL * Fasting triglycerides \<350 mg/dL * ≤10% change in body weight in the prior 6 months Exclusion Criteria: * Type 1 or type 2 diabetes or fasting blood glucose ≥126 mg/dL * Prescription of anti-hypertensive, lipid lowering or glucose lowering drugs * Intake of supplements that affect the outcomes of interest and unwilling to cease during the study period * Diagnosed liver, kidney, or autoimmune disease…
Interventions
- DrugWhole Egg
Whole Large, Grade A Egg
Location
- The Pennylvania State UniversityUniversity Park, Pennsylvania