Effects of Wild Blueberry Consumption on Gut, Brain, and Cardiovascular Health in Non-Hispanic Black and White Adults With High Blood Pressure
Georgia State University
Summary
The purpose of the study is to determine the effectiveness of wild blueberries on cardiovascular health, cognitive function, and gut microbiota composition in non-Hispanic Black and White adults with elevated blood pressure.
Description
Hypertension (HTN), or high blood pressure (BP) is a major modifiable risk factor for heart disease, the leading cause of death worldwide. In the U.S., 121.5 million adults have high BP and only 25% have their BP under control. The 2022 Heart Disease and Stroke Statistics indicated that the incidence of high BP was higher among non-Hispanic Black (NHB) compared to non-Hispanic White (NHW) adults. Berries are rich in fiber and phytochemicals and have several health benefits. A 14-year follow-up of the Nurses' Health Study I and II and the Health Professional Follow-Up Study revealed a significa…
Eligibility
- Age range
- 45–65 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Individuals 45-65 years of age * Diagnosis of elevated blood pressure or stage 1 hypertension (systolic blood pressure = 120-139 mmHg and/or diastolic blood pressure = 80-89 mmHg) for at least 6 months * BMI 25-35 kg/m2 via anthropometric measurements. * Ability to give consent Exclusion Criteria: * Allergies to berries * Use of one hypertensive drug for less than three months * Use of more than one anti-hypertensive or statin drug, insulin, antibiotics, and anti-inflammatory drugs, active cancer, gastrointestinal, renal, cardiovascular, thyroid, and neurological disor…
Interventions
- Dietary SupplementWild Blueberry
Daily consumption of 22 g of freeze-dried wild blueberry freeze-dried powder for 8 weeks
- Dietary SupplementPlacebo
Daily consumption of 22 g of freeze-dried macronutrient-matched placebo powder for 8 weeks
Location
- Georgia State UniversityAtlanta, Georgia