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Defining the Brain Phenotype of Children With 7q11.23 Copy Number Variation, Including Williams Syndrome and 7q11.23 Duplication Syndrome

Background: \- Little is known about how the brain changes during childhood and adolescence, how genes affect this process, or how the brains of people with 7…

Williams SyndromeDuplication

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Mental Health (NIMH)NCT01132885

Observational

Launching the Houston-HVIP: Developing and Evaluating a Hospital-Based Intervention to Reduce Recurrent Violence

A prior violent injury is one of the strongest predictors of future violent injury, highlighting the importance of effective hospital-based interventions to pr…

Firearm Injury

Estimated

~$10 – $750

Actual pay is set by the research site.

The University of Texas Health Science Center, HoustonNCT06263647

Phase 1

A Phase I Dose-escalation Study of Preoperative Radiation Therapy in Participants With Resectable Recurrent Abdominal Adrenocortical Carcinoma

Background: Adrenocortical carcinoma (ACC) is a rare cancer of the adrenal glands. ACC often returns after tumors are removed with surgery. Less than 35% of p…

Adrenocortical Carcinoma (ACC)Recurrent Adrenocortical Carcinoma (ACC)Recurrent Abdominal Adrenocortical Carcinoma (ACC)+2 more

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT06487481

Phase 2

RELIEVE (RandomizEd triaL of Intravesical xEomin for Incontinence Via the VibE System) - a Randomized, Prospective, Multicenter, Double Blind, Placebo and Sham Controlled Study to Assess the Safety and Efficacy of NT 201 Intravesical Administration Using Vibe System in the Treatment of Female Participants Suffering From Idiopathic Overactive Bladder

This Phase 2b study is a prospective, multicenter, double blind, randomized, placebo and sham controlled trial to assess the safety, efficacy and dose response…

Overactive Bladder (OAB)

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Vensica Therapeutics Ltd.NCT07553065

Phase 1

A Phase I Study to Assess Safety and Feasibility of IL-8 Receptor Modified Patient-Derived Activated CD70 CAR T Cell Therapy in Adults With Brain Metastases From Primary Cancers (IMPACT-MET)

This is a Phase I Study evaluating the safety and feasibility of IL-8 receptor-modified patient-derived activated CD70 CAR T cells in adult patients with brain…

Brain Metastases

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of FloridaNCT07569263

Phase 1

Phase I/II Trial of Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms

Background: Myelodysplastic syndrome (MDS) and myelodysplastic/myeloproliferative neoplasm (MDS/MPN) are blood disorders that can cause serious complications …

Myelodysplastic Syndromes

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT06303193

Tissue Procurement Protocol for the Developmental Therapeutics Clinic, National Cancer Institute (NCI)

Background: -Patients who are being evaluated and/or treated at the NIH Clinical Center and adult patients at participating sites will be entered onto this ti…

NeoplasmsLymphomasMultiple Myeloma+1 more

Estimated

~$10 – $675

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT00900198

Phase 1

Examining the Role of Tolerance on Dose-dependent Effects of Acute THC on Oculomotor and Cognitive Performance

The purpose of this research is to determine the extent to which oculomotor function accurately detects THC-impairment, if cannabis use experience impacts this…

Cannabis UseImpaired DrivingCognitive Impairment

Estimated

~$500 – $7,500

Actual pay is set by the research site.

Johns Hopkins UniversityNCT06351540

Observational

Neuromodulation and Neurorehabilitation for Treatment of Functional Deficits After mTBI and PTSD

This study will determine (i) the magnitude of immediate and sustained effects of a current clinical standard interactive computer attention processing trainin…

Mild Traumatic Brain InjuryPost Traumatic Stress Disorder

Estimated

~$10 – $750

Actual pay is set by the research site.

Northwestern UniversityNCT03819608

Phase 2

A Randomized Phase II Trial of ASTX727 With Standard Duration Versus Shorter Duration of Venetoclax in Genomically Heterogenous AML Among Adults Aged 60 or Older and Less Fit for Intensive Therapy: A MyeloMATCH Substudy

This phase II MyeloMATCH treatment trial compares ASTX727 with standard duration versus shorter duration of venetoclax for the treatment of newly diagnosed acu…

Acute Myeloid Leukemia

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT07437950

Natural History of Trisomy 8-Associated Autoinflammatory Disease (TRIAD) and Related Disorders

Background: Trisomy 8 mosaicism is a genetic disorder that can increase inflammation in the body. Symptoms include fevers; sores or ulcers in the mouth, diges…

Trisomy 8 MosaicismTrisomy 8 Associated Autoinflammatory DiseaseMucosal Ulcerations

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Allergy and Infectious Diseases (NIAID)NCT07683104

Phase 1

A Phase I Study to Evaluate the Safety and Pharmacokinetics of RO7890597 Following Single and Multiple Ascending Doses, and the Effects of Food, Proton-Pump Inhibition, And CYP3A Inhibition in Healthy Adult Volunteers

This study will evaluate the safety, pharmacokinetics (PK), and activity of single and multiple doses of RO7890597 compared with placebo in healthy volunteers.…

Healthy Volunteers

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Genentech, Inc.NCT07797478