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26,914 recruiting studies available now

Estrogen for Quality-of-Life and Immune Modulation in Prostate Cancer (EQUIP)

This phase II trial compares giving estrogen with an androgen receptor signaling inhibitor to standard of care luteinizing hormone-releasing hormone (LHRH) ana…

Castration-Sensitive Prostate AdenocarcinomaMetastatic Castration-Sensitive Prostate AdenocarcinomaStage IVB Prostate Cancer AJCC v8

Estimated

~$10 – $6,250

Fred Hutchinson Cancer CenterNCT07466498

Etiologic Investigation of Cancer Susceptibility in Inherited Bone Marrow Failure Syndromes: A Natural History Study

Background: A prospective cohort of Inherited Bone Marrow Failure Syndrome (IBMFS) will provide new information regarding cancer rates and types in these diso…

Diamond Blackfan AnemiaDyskeratosis CongenitaFanconi Anemia+2 more

Estimated

~$10 – $675

National Cancer Institute (NCI)NCT00027274

Phase 1

Effect of Short-Term Oral Eplerenone on Intraocular Pressure in Healthy Adult Volunteers: A Randomized, Double-Masked, Placebo-Controlled Crossover Study

The goal of this clinical trial is to determine whether eplerenone lowers eye pressure in healthy adults. Eplerenone is a medication approved by the U.S. Food …

Intraocular Pressure (IOP)Healthy Adult

Estimated

~$10 – $6,250

University of FloridaNCT07795762

Phase 2

A Phase 2a Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-8690 in Adult Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this protocol is to evaluate the efficacy of MK-8690 in participants with moderately to severely active ulcerative colitis. The primary hypothes…

Colitis UlcerativeUlcerative Colitis

Estimated

~$10 – $8,750

Merck Sharp & Dohme LLCNCT07463183

Phase 3

A Randomized, Double-blind, Parallel-group Phase III Study to Evaluate the Efficacy, Safety, and Tolerability of Elecoglipron Alone or in Combination With Dapagliflozin Compared With Placebo in Adults With Type 2 Diabetes Mellitus (Eluminate-1)

The purpose of this study is to evaluate the efficacy, safety, and tolerability of elecoglipron alone or in combination with dapagliflozin compared with placeb…

Type 2 Diabetes Mellitus

Estimated

~$10 – $7,500

AstraZenecaNCT07662044

Phase 1

A Phase 1, Open-label, Dose Escalation and Dose Expansion Study, to Investigate the Safety, Tolerability, and Pharmacokinetic Profile of AB521 Monotherapy and Combination Therapies in Participants With Clear Cell Renal Cell Carcinoma and Other Solid Tumors

The purpose of this study is to evaluate the safety and tolerability of: * casdatifan when taken alone in participants with advanced solid tumor malignancies …

Clear Cell Renal Cell CarcinomaSolid Tumors

Estimated

~$10 – $8,750

Arcus Biosciences, Inc.NCT05536141

International Calcium Release Deficiency Syndrome Registry

Calcium Release Deficiency Syndrome (CRDS) is a newly discovered genetic arrhythmia syndrome that confers a risk of life-threatening arrhythmias secondary to R…

Calcium Release Deficiency Syndrome

Estimated

~$10 – $1,125

Population Health Research InstituteNCT06508164

Defining the Natural History of Squamous Cell Carcinoma in Fanconi Anemia

Background: Fanconi anemia (FA) is an inherited disorder. People with FA are more likely to get certain cancers, especially squamous cell carcinoma (SCC). The…

Fanconi AnemiaInherited Bone Marrow Failure Syndrome

Estimated

~$10 – $675

National Cancer Institute (NCI)NCT05687149

Observational

Studying User Sensory Experiences and Smoking Behavior of IQOS Heated Tobacco Products to Improve Harm Reduction Among Adult Cigarette Smokers

This clinical trial aims to evaluate user sensory experiences and smoking behavior when using IQOS heated tobacco products (HTPs) among adults who smoke cigare…

Tobacco

Estimated

~$10 – $6,250

Ohio State University Comprehensive Cancer CenterNCT07688304

Elafibranor Pregnancy Surveillance Program: A Post Marketing, Long Term, Multi-Center, Noninterventional, and Descriptive Study to Characterize Pregnancy and Maternal Complications and to Describe Effects on the Developing Fetus, Neonate and Infant Among Individuals Exposed to Elafibranor During Pregnancy

The study will include participants who were exposed to at least one dose of elafibranor either within the three weeks before conception or at any time during …

Determination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin Labeling

Background: Sickle cell disease (SCD) is an inherited disorder of the blood. SCD causes red blood cells (RBCs) to die early. This can lead to a shortage of he…

Sickle Cell DiseaseThalassemiaHemoglobinopathy

Estimated

~$10 – $5,625

National Heart, Lung, and Blood Institute (NHLBI)NCT06313398

Phase 3

A Phase 3, Multinational, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy, Safety, and Clinical Outcomes of Pemvidutide in Subjects With Noncirrhotic Metabolic Dysfunction-Associated Steatohepatitis (MASH)

Phase 3, multicenter, multinational, 2-cohort, randomized, double-blind, placebo controlled, parallel-group pivotal study to evaluate the efficacy, safety, and…

Metabolic Dysfunction-Associated Steatohepatitis (MASH)

Estimated

~$10 – $8,750

Altimmune, Inc.NCT07795164