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27,370 recruiting studies available now

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Neuroimaging in Healthy Aging and Senile Dementia (HASD_IND)

To identify factors that signal the transition from asymptomatic (preclinical) to symptomatic Alzheimer disease (AD).

Alzheimer Disease

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Tammie L. S. Benzinger, MD, PhDNCT04579120

Phase 1

A PHASE 1/2A RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED, SINGLE AND MULTIPLE ASCENDING DOSE STUDY TO INVESTIGATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF MET233 CO-ADMINISTERED WITH MET097 IN ADULT PARTICIPANTS WITH OBESITY OR OVERWEIGHT INCLUDING PARTICIPANTS WITH TYPE 2 DIABETES MELLITUS

This study is designed to test how well the combination of MET233 with MET097 works to treat individuals with obesity or overweight with or without diabetes.

Obesity and Obesity-related Medical Conditions

Estimated

~$500 – $11,250

Actual pay is set by the research site.

PfizerNCT06924320

Consortium for Gut-Brain Communication in Parkinson's Disease Master Protocol

The purpose of this research study is to identify the role that the gut-brain axis, the group of nerves that connect the brain and gut, plays in Parkinson's di…

Parkinson Disease (PD)PARKINSON DISEASE (Disorder)Gut Microbiome+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Duke UniversityNCT07567794

Phase 4

A Phase IV Randomized, Single-Blind Trial of Liposomal Bupivacaine (Exparel®) for Pain Control in Costal Cartilage Harvest

The purpose of this study is to find out whether injecting the U.S. Food and Drug Administration (FDA) approved drug EXPAREL®, a long acting (approximately 96 …

Nasal Surgery

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Mayo ClinicNCT05285566

Mechanisms of Increased Disease Severity in AD Patients With the IL-4Ra R576 Polymorphism

This protocol is primarily looking to see if the IL-4Ra R576 polymorphism is associated with increased clinical, immunological and microbial markers of disease…

Atopic Dermatitis

Estimated

~$10 – $750

Actual pay is set by the research site.

Boston Children's HospitalNCT04455906

Phase 1

Phase 1/2a Open-Label Clinical Trial Evaluating VBC106, an FRα- and MSLN-Directed Bispecific Antibody Drug Conjugate, in Participants With Advanced Malignant Solid Tumors

This is a multicenter, open-label, multiple-dose, FIH Phase 1/2a trial. The Phase 1 portion adopts BOIN design to identify the MTD and/or RP2D with potential b…

Participants With Advanced Solid Tumor Malignancies

Estimated

~$150 – $4,200

Actual pay is set by the research site.

VelaVigo Bio IncNCT07686068

Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge

Background: Malaria is a serious infection caused by a parasite. People get malaria when an infected mosquito bites them. Malaria can cause major health and s…

Malaria

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Allergy and Infectious Diseases (NIAID)NCT02639299

Observational

Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis Stress

The objectives of this study are to determine if the 'Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis Stres…

LupusDermatomyositis, JuvenileDermatomyositis+3 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Duke UniversityNCT06999109

Non-Invasive Monitoring Methods in Patients With Acute Brain Injury

Life-threatening mass effect (LTME) arises when brain swelling displaces or compresses crucial midline structures subsequent to acute brain injuries (ABIs) lik…

Brain Injury, Acute

Estimated

~$10 – $750

Actual pay is set by the research site.

Boston Medical CenterNCT06504238

Observational

Prospective, Randomized, Controlled Trial to Evaluate the Effect of Preoperative Penile Traction Therapy on Post-penile Implant Length and Patient Satisfaction

The goal of this study is to determine whether or not the use of a penile traction therapy device known as RestoreX prior to implantation of a penile prosthesi…

Erectile Dysfunction

Estimated

~$10 – $1,125

Actual pay is set by the research site.

J. Peter Rubin, MDNCT07053826

Phase 2

A Phase 2/3, Multicenter, Open-Label Phase Followed by a Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Infigratinib in Children With Hypochondroplasia: ACCEL 2/3

ACCEL2/3 is a Phase 2/3 study. The purpose of the Phase 2 portion of the study (ACCEL2/3) is to evaluate the efficacy and safety of infigratinib in children wi…

Hypochondroplasia

Estimated

~$75 – $2,800

Actual pay is set by the research site.

QED Therapeutics, a BridgeBio companyNCT06873035

Longitudinal Effects of E-cigarette Use on Cardiovascular and Pulmonary Health

Electronic nicotine delivery systems (ENDS) are used by millions of Americans, however their long-term health effects are unknown. This research proposal will …

Electronic Cigarette Use

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Wisconsin, MadisonNCT06610838