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27,407 recruiting studies available now

A Phase I Trial of Revumenib in Combination With 7+3 (7 Days of Cytarabine and 3 Days of Daunorubicin) + Midostaurin Induction Chemotherapy for the Frontline Treatment of NPM1 and FLT3 Mutated AML

This research is being conducted to determine a safe and effective dose of revumenib that can be given in combination with standard induction (initial therapy …

Acute Myeloid LeukemiaAML, AdultAML With Gene Mutations+2 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Richard Stone, MDNCT06313437

Observational

Neural Mechanism of the Effect of Acupuncture on Hypertension

Based on previous published research in animals and human, the investigators hypothesize that electroacupuncture (EA) will have a positive effect on hypertensi…

Hypertension

Estimated

~$10 – $750

Actual pay is set by the research site.

University of California, IrvineNCT00932139

Parametric Response Mapping (PRM) for the Detection of Chronic Lung Injury in Hematopoietic Cell Transplant Recipients. A Multi-center, Observational Trial.

The study will have two separate patient cohorts: Cohort 1 will include patients with newly diagnosed chronic graft versus host disease (GVHD), whereas cohort …

Chronic Lung DiseaseHematopoietic Cell TransplantationGraft Versus Host Disease

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Michigan Rogel Cancer CenterNCT05866302

Phase 3

A Phase 3, Randomized, Open-label, Multicenter, Controlled Study to Evaluate the Efficacy and Safety of Zanidatamab in Combination With Physician's Choice Chemotherapy Compared to Trastuzumab in Combination With Physician's Choice Chemotherapy for the Treatment of Participants With Metastatic HER2-positive Breast Cancer Who Have Progressed on, or Are Intolerant to, Previous Trastuzumab Deruxtecan Treatment

The efficacy and safety of zanidatamab in combination with physician's choice of chemotherapy compared with trastuzumab in combination with physician's choice …

Metastatic HER2-positive Breast Cancer

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Jazz PharmaceuticalsNCT06435429

Studies of Disorders With Increased Susceptibility to Fungal Infections

Background: \- Researchers are interested in studying disorders that make individuals more susceptible to fungal infections, specifically infections with the …

Fungal InfectionsPrimary Immune Deficiencies

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Allergy and Infectious Diseases (NIAID)NCT01222741

Phase 1

A Phase I/II Trial of Reduced Intensity Conditioning and Familial HLA-Mismatched Bone Marrow Transplantation in Children With Non-Malignant Disorders

This study is designed to estimate the efficacy and toxicity of familial HLA mismatched bone marrow transplants in patients with non-malignant disease who are …

Severe Sickle Cell DiseaseBone Marrow Failure SyndromesMetabolic Disorders+3 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Washington University School of MedicineNCT03128996

Phase 3

A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Safety and Efficacy of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease

This is a Phase 3, randomized, double-blind, placebo-controlled, parallel group study to evaluate the safety and efficacy of KarXT in male and female subjects …

Psychosis Associated With Alzheimer's Disease

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Karuna Therapeutics, Inc., a Bristol Myers Squibb companyNCT06126224

Phase 1

A Phase 1/2, Open-label Study of PD-1 Knockout Tumor-infiltrating Lymphocytes (IOV-4001) in Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer

This is a study to investigate the efficacy and safety of an infusion of IOV-4001 in adult participants with unresectable or metastatic melanoma or advanced no…

Unresectable MelanomaMetastatic MelanomaStage III Non-small Cell Lung Cancer+1 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Iovance Biotherapeutics, Inc.NCT05361174

Observational

A Longitudinal, Randomized-Controlled Experiment of Healthy Food Policies in Online Retail Settings

Unhealthy diets significantly contribute to major preventable chronic diseases including type 2 diabetes, obesity, heart disease and stroke, which disproportio…

Chronic Disease

Estimated

~$10 – $750

Actual pay is set by the research site.

University of PennsylvaniaNCT07422922

Phase 1

A Phase 1 Clinical Trial to Evaluate the Safety and Immunogenicity of the V2 Apex-Directed Immunogens DV201P-RNA and DV202B1-RNA in Adult Participants Without HIV

This is a phase 1, multicenter, open-label, dose escalation, first-in-human (FIH) trial to evaluate the safety and immunogenicity of DV201P-RNA and DV202B1-RNA…

HIV

Estimated

~$500 – $6,750

Actual pay is set by the research site.

National Institute of Allergy and Infectious Diseases (NIAID)NCT07390474

Phase 4

Exploratory Use of CMV Immunoglobulin in High Risk (D+R-) Transplant Recipients at the End of Antiviral Prophylaxis to Decrease the Risk of Late CMV Infection

This study is being done to find out if administering CytoGam® after the end of standardly prescribed preventive antiviral treatment can help transplant recipi…

CytomegalovirusOrgan TransplantKidney Transplant; Complications+2 more

Estimated

~$25 – $1,500

Actual pay is set by the research site.

Camille N. Kotton, MDNCT06958796

Observational

Personalized Cancer Support for Young Adults

This pilot clinical trial is intended to compare the effect of a psychosocial support tool for young adult (YA)cancer survivors - including high-quality inform…

Differentiated Thyroid Gland CarcinomaMalignant Testicular NeoplasmMelanoma+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Michigan Rogel Cancer CenterNCT07529080