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Tumor Treating Fields: Pilot Study of Adjuvant Treatment for Brainstem Gliomas

This clinical trial tests the safety and side effects of tumor treating fields in treating patients with gliomas located in the brainstem. Optune is a wearable…

Glioma

Estimated

~$10 – $750

Actual pay is set by the research site.

Emory UniversityNCT05310448

Phase 3

Phase III Trial of Neoadjuvant Durvalumab (NSC 778709) Plus Chemotherapy Versus Chemotherapy Alone for Adults With MammaPrint High 2 Risk (MP2) Hormone Receptor (HR) Positive / Human Epidermal Growth Factor Receptor (HER2) Negative Stage II-III Breast Cancer

This phase III trial compares the addition of an immunotherapy drug (durvalumab) to usual chemotherapy versus usual chemotherapy alone in treating patients wit…

Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8HER2-Negative Breast Carcinoma+1 more

Estimated

~$50 – $1,350

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT06058377

Observational

Accelerated Resolution Therapy for Early Maladaptive Grief: A Clinical Trial

The purpose study is to test the effects of accelerated resolution therapy (ART) on pre-loss grief and prolonged grief disorder among older adult family caregi…

Grief

Estimated

~$10 – $750

Actual pay is set by the research site.

Mayo ClinicNCT05624879

Pain Phenotyping of Rheumatic Diseases - An Observational Study

Background: Rheumatic diseases can affect the joints, ligaments, tendons, bones, muscles, and skin. They can also cause inflammation, damage body tissues, and…

Rheumatic DiseasesLupus Erythematosus, SystemicLupus Vasculitis, Central Nervous System+5 more

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)NCT07829497

Phase 1

A Phase 1 Study of VX-581 in Healthy Subjects and in Subjects With Cystic Fibrosis

The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of single dose of VX-581 and multiple ascending doses of VX-581 alone a…

Cystic Fibrosis

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Vertex Pharmaceuticals IncorporatedNCT07283770

Phase 2

A Phase 2 Trial of PD-L1 t-haNK, NAI IL-15 Superagonist (Anktiva), and Cetuximab for Immunotherapy-treated Patients With Recurrent, Metastatic HNSCC (QUILT-505)

The purpose of this research study is to test the safety and efficacy of the combination of PD-L1 t-haNK (modified immune cells), NAI (a manufactured protein t…

Head and Neck CancerHead and Neck Squamous Cell CarcinomaMetastatic Head and Neck Cancer+3 more

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Dana-Farber Cancer InstituteNCT06239220

Observational

DCE-MRI Guided Neoadjuvant Chemotherapy for Borderline Resectable Pancreatic Cancer

The goal of this study is to test whether chemotherapy guided by a new imaging method named DCE-MRI can more effectively reduce a pancreatic tumor, enabling cu…

Borderline-resectable Pancreatic Cancer

Estimated

~$10 – $750

Actual pay is set by the research site.

Ohio State UniversityNCT06173310

Phase 3

A Phase 3, Multicenter, Open-Label, Randomized Trial to Compare the Efficacy and Safety of Elritercept Versus Epoetin Alfa for the Treatment of Anemia Due to IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes in ESA-naïve Adult Participants Who Require Red Blood Cell Transfusions

The main aim of this study is to assess how much elritercept reduces the need for RBC (red blood cell) transfusions and improves hemoglobin blood values in add…

Myelodysplastic SyndromeAnemia

Estimated

~$50 – $2,250

Actual pay is set by the research site.

TakedaNCT07422480

Phase 2

A Phase II Study of Combination Bevacizumab and PRGN-2012 in Adults With Recurrent Respiratory Papillomatosis (RRP)

Background: Recurrent respiratory papillomatosis (RRP) is a rare disease that causes wart-like growths called papillomas to grow in the airway, most often in …

Respiratory Recurrent Papillomatosis (RRP)Human Papillomavirus (HPV)Papillomavirus Infection+3 more

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT07756840

Phase 1

A Phase I Study of SNDX 5613 (Revumenib) as Post-Transplant Maintenance After Allogeneic Hematopoietic Cell Transplant in Patients With KMT2A-Rearranged or NPM1-Mutated Acute Leukemia

This phase I trial tests the safety, side effects, best dose and effectiveness of revumenib in treating patients with acute leukemia after allogeneic stem cell…

Acute LeukemiaAcute Leukemia of Ambiguous LineageAcute Lymphoblastic Leukemia+5 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

City of Hope Medical CenterNCT06575296

Phase 2

Presurgical Phase II Study of Talazoparib in Combination With Enzalutamide in de Novo Metastatic to Lymph Nodes Prostate Cancer

To learn about the effectiveness of adding talazoparib to the standard of care treatment combination of androgen ablation therapy (hormone therapy, also known …

Prostate Cancer

Estimated

~$75 – $2,000

Actual pay is set by the research site.

M.D. Anderson Cancer CenterNCT05873192

Observational

Improving Jail Response to the Overdose Crisis: A Hybrid Trial of Jail ECHO to Improve MOUD Implementation and Public Health Outcomes

This project tests a training strategy to help rural jails start or increase their use of medications to treat opioid use disorder (MOUD - methadone, buprenorp…

Opioid Abuse (Disorder)

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Massachusetts, WorcesterNCT07637994