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27,069 recruiting studies available now

Phase IV Study of the Pharmacokinetics of Long-Acting Injectable Cabotegravir and Rilpivirine in Pregnant and Postpartum Women With HIV in the United States

Phase IV, multi-site, open-label, non-randomized study of the pharmacokinetics (PK) of long-acting injectable cabotegravir and rilpivirine (CAB LA + RPV LA) du…

HIV -1 Infection

Estimated

~$10 – $750

International Maternal Pediatric Adolescent AIDS Clinical Trials GroupNCT07637942

Phase 4

Phase 4 Study to Evaluate the Safety and Effectiveness of ELEVIDYS in Patients With Duchenne Muscular Dystrophy Treated in a Post-Marketing Setting (ENHANCE)

The primary objective of this study is to evaluate acute liver injury (ALI) rates associated with ELEVIDYS with the addition of sirolimus as an adjunct prophyl…

Duchenne Muscular Dystrophy

Estimated

~$10 – $8,750

Sarepta Therapeutics, Inc.NCT07542314

Observational

Randomized Controlled Trial of Online Pain Education Programs for Inflammatory Bowel Disease

Through a pilot randomized controlled trial (RCT), we aim to test the feasibility and preliminary impact of two online pain educations programs among adult pat…

Crohn's DiseaseUlcerative Colitis (UC)Inflammatory Bowel Disease (Crohn's Disease; Ulcerative Colitis)

Estimated

~$10 – $6,250

Cedars-Sinai Medical CenterNCT07671313

Phase 3

Liposomal Amphotericin B and Flucytosine Antifungal Strategy for Talaromycosis (LAmB-FAST)

LAmB-FAST is a factorial randomized controlled trial simultaneously testing two interventions in one trial. LAmB-FAST seeks to inform treatment guidelines on t…

Talaromycosis

Estimated

~$10 – $6,250

Duke UniversityNCT06525389

Phase 2

Group Music Therapy for Chronic Pain Management in Active Duty Service Members With Chronic Pain: A Randomized Controlled Trial

This randomized controlled trial will evaluate the effectiveness of an 8-week group music therapy intervention for active duty service members with chronic pai…

Chronic Pain

Estimated

~$10 – $6,250

Henry M. Jackson Foundation for the Advancement of Military MedicineNCT07755540

Phase 2

Adjuvant Pembrolizumab and Hypofractionated Radiation Therapy for the Treatment of Mucosal Melanoma

This is an open-label, single center, one cohort, non-randomized, phase II study. The aim is to evaluate the efficacy and safety of the combination of hypofrac…

Mucosal Melanoma of the Head and Neck

Estimated

~$10 – $6,250

Washington University School of MedicineNCT04318717

Phase 1

SIngle-Stage, Open-Label, Safety and Efficacy Study of Adeno-Associated Virus Encoding Human Aromatic L-Amino Acid Decarboxylase by Magnetic Resonance MR-guided Infusion Into Midbrain in Pediatric Patients With AADC Deficiency

The overall objective of this study is to determine the safety and efficacy of AAV2-hAADC delivered to the substantia nigra pars compacta (SNc) and ventral teg…

AADC Deficiency

Estimated

~$10 – $7,500

Krzysztof BankiewiczNCT02852213

Observational

Single Site Implementation Pilot Trial of Base, Enhanced, and Sustainment Implementation Toolkits for Diabetes Coaching for Families With an Adolescent With Type 1 Diabetes

The goal of this study is to learn if toolkits of implementation strategies (e.g., provider and staff education, clear plan for how to refer and bill) help ped…

Implementation ScienceType 1 Diabetes in AdolescenceImplementation Strategies

Estimated

~$10 – $6,250

Nemours Children's ClinicNCT07766811

Observational

Intelligent Clinical Decision Support for Preoperative Blood Management: A Cluster-Randomized Clinical Trial

20 million patients have surgery in the United States every year, with approximately 1 million of those patients requiring life-saving blood transfusion. Presu…

Surgery

Estimated

~$10 – $6,250

Washington University School of MedicineNCT07223853

Phase 3

A Phase 3, Open-label Trial to Evaluate the Efficacy, Safety and Tolerability of Switching From the Glucagon-like Peptide-1 Receptor Agonists to Maridebart Cafraglutide in Adult Participants With Obesity or Overweight

Efficacy, safety and tolerability of switching from GLP-1RA to maridebart cafraglutide in adults with obesity or overweight.

Obesity or Overweight

Low Intensity Focused Ultrasound Stimulation in Stroke Patients - Parameter Optimization

The goal of this research study is to optimize the parameter of Low-Intensity Focused Ultrasound Stimulation (LIFUS) that is most effective in changing cortica…

StrokeArm Weakness as a Consequence of StrokeUpper Extremity Hemiparesis+2 more

Estimated

~$10 – $6,250

Duke UniversityNCT07220005

Phase 1

Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)

Background: In people with multiple sclerosis (MS), brain and cerebrospinal fluid (CSF) biomarkers indicate inflammation or disease. Researchers want to see i…

Multiple Sclerosis

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT03109288