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27,171 recruiting studies available now

A Phase 2b/3 Randomized Open-Label Dose-Selection Study With Open-Label Extension and Randomized Double-Blind, Placebo-Controlled Study With Open-Label Extension to Evaluate the Safety and Efficacy of Choline Chloride for Injection (Low Dose and High Dose) Versus Placebo in Adolescents and Adults With Intestinal Failure Receiving Long-Term Parenteral Support

TARA-001-301 is a Phase 2b/3 randomized Open-Label Dose-Selection study with an Open-Label Extension and randomized Double-Blind, Placebo-Controlled Study with…

Choline DeficiencyLiver Injury

Estimated

~$10 – $8,750

Protara TherapeuticsNCT06910943

Observational

Optimizing a Closed-loop Digital Meditation Intervention for Remediating Cognitive Decline and Reducing Stress in Older Adults

The goals of the proposed research are to first determine the minimal and/or optimal dose of a digital intervention required for cognitive enhancement, and the…

AgingMCICognitive Decline

Estimated

~$10 – $5,625

University of California, San FranciscoNCT06397469

Phase 1

A Single- and Multiple-Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LY3954068 in Patients With Early Symptomatic Alzheimer's Disease

The main purpose of this study is to evaluate the safety of LY3954068 in participants with early symptomatic Alzheimer's Disease (AD). The study will also inve…

Alzheimer Disease

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT06297590

Phase 4

MIRICURE: Mirikizumab With Curettage and Repair (Closure) for Perianal Fistulizing Crohn's Disease

This Phase 4, single-arm, open-label study will evaluate the effectiveness and safety of mirikizumab combined with surgical curettage and closure in adults wit…

Crohn's DiseasePerianal Fistula

Estimated

~$10 – $6,250

Icahn School of Medicine at Mount SinaiNCT07782021

Longitudinal Study of Patients With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Post-Acute Sequelae of COVID-19 (PASC)

This study will examine how common Long COVID is and how symptoms may persist over time in people who have previously had COVID-19. Researchers will collect in…

SARS CoV-2 Post-Acute Sequelae

Estimated

~$10 – $750

University of North Carolina, Chapel HillNCT07781501

Phase 1

BRE-06: Study to Increase Tolerance to Aromatase Inhibitors for Patients With Early-Stage Hormone Receptor Positive Breast Cancer Who Developed Hypoactive Sexual Desire Disorder

This study is open to women who have early-stage breast cancer and are on aromatase inhibitor (AI) therapy, and who have hypoactive sexual desire disorder (HSD…

Early-stage Breast CancerHypoactive Sexual Desire DisorderHormone Receptor Positive Breast Carcinoma+1 more

Estimated

~$10 – $6,250

University of Illinois at ChicagoNCT07596212

Observational

Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and Muscle

Background: \- Magnetic resonance imaging (MRI) is a widely used scanning technique to obtain images of the human body and evaluate activity in the brain. A p…

Brain MappingHealthy Volunteer

Estimated

~$10 – $5,625

National Institute of Mental Health (NIMH)NCT01266577

Phase 1

A Phase 1, Single-dose, Open-label Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Adagrasib (BMS-986503) in Healthy Participants of Japanese Descent

The aim of this study is to assess the pharmacokinetics, safety and tolerability of single-dose Adagrasib (BMS-986503) in healthy participants of Japanese desc…

Healthy Participants

Estimated

~$10 – $8,750

Mirati Therapeutics Inc.NCT07723118

PREVENT ALL ALS - Longitudinal Biomarker Study for Participants Who Are Genetically at Risk for Amyotrophic Lateral Sclerosis (ALS)

The ALL ALS Clinical Research Consortium is establishing research to collect a wide range of samples, clinical information and measurements from Amyotrophic La…

Amyotrophic Lateral Sclerosis

Estimated

~$10 – $750

St. Joseph's Hospital and Medical Center, PhoenixNCT06581861

Phase 1

A Protocol to Assess the Safety, Efficacy, and Pharmacokinetics of Continuous Subcutaneous Administration of Low-dose Lenalidomide (STAR-LLD) for the Treatment of Multiple Myeloma (MM)

Primary Objective • Assess the safety and tolerability of low-dose lenalidomide administered by continuous subcutaneous (SC) infusion (STAR-LLD) in combination…

Multiple Myeloma

Estimated

~$10 – $8,750

Starton Therapeutics, IncNCT06087653

Phase 1

UPdated Disease Monitoring And Treatment for Enhanced Outcomes for Pediatric AML: A Pilot Trial

This research study investigates the tolerability of substituting two cycles of chemotherapy into the standard pediatric acute myeloid leukemia (AML) chemother…

Acute Myeloid LeukemiaPediatric AML

Estimated

~$10 – $6,250

Baylor College of MedicineNCT07059975

Deep Learning for Algorithmic Detection of Pulmonary Hypertension Using a Combined Digital Stethoscope and Single-lead Electrocardiogram

The major goal of the study is to determine whether phonocardiography (using the Eko DUO stethoscope which can capture a three lead ECG reading) can present fe…

Pulmonary Hypertension

Estimated

~$10 – $1,050

Eko Devices, Inc.NCT05873387