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Randomized Directly Observed Therapy Study to Interpret Clinical Trials of Doxy-PEP

Rates of bacterial sexually transmitted infections (STIs) are rising globally, demanding innovative interventions beyond the scope of current efforts to preven…

Sexually Transmitted Diseases, Bacterial

Estimated

~$10 – $5,625

University of California, San FranciscoNCT06414408

Engaging Diverse and Underserved Communities in Cancer Awareness Training and Education (EDUCATE)

The University of California Davis, Comprehensive Cancer Center's (UCDCCC) Office of Community Outreach and Engagement (OCOE) serves the 19 catchment counties …

Cancer Awareness and Prevention Education

Estimated

~$10 – $750

University of California, DavisNCT05761782

Phase 1

A Phase 1/2, Multicenter, Open-Label, Dose-Escalation, Safety, Tolerability, and Clinical Activity Study of a Single Dose of JAG201 Gene Therapy Delivered Via Intracerebroventricular Administration in Participants With SHANK3 Haploinsufficiency

This is a Phase 1/2, first in human, open-label, dose-escalation study to evaluate the safety, tolerability, and clinical activity of a single dose of JAG201 a…

SHANK3 HaploinsufficiencyPhelan-McDermid Syndrome

Estimated

~$10 – $8,750

Jaguar Gene Therapy, LLCNCT06662188

A Prospective, Single-Center Study to Test the AdaptDx Pro Agreement in Rod Intercept Time With the AdaptDx in Healthy Subjects With Normal Vision (FlashBack)

The purpose of this study is to test the AdaptDx Pro agreement in Rod Intercept (RI) time with the AdaptDx tabletop (AdaptDx) in healthy subjects with normal v…

Healthy Adult Participants

Estimated

~$10 – $1,050

AdaptDx, Inc.NCT07803588

Phase 2

A Phase II Trial of Focal Ultrahypofractionated Stereotactic Radiation Therapy for the Treatment of Unifocal Prostate Cancer

Background: The current standard treatment of prostate cancer is either surgery or radiation. Typically, this includes either the removal or radiation of the …

Prostatic NeoplasmsProstate CancerProstate Adenocarcinoma

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT05616650

Phase 1

Alpelisib Challenge Test (ACT) for Assessment of Pancreatic β-Cell Reserve, Pilot & Feasibility Study

The goal of this study is to test a potentially easier method for measuring how much insulin a person is capable of producing than the current gold-standard me…

Insulin ResistanceType 2 DiabetesObesity & Overweight+1 more

Estimated

~$10 – $6,250

Columbia UniversityNCT07778524

Phase 1

A Phase I, Open-Label, Escalation and Expansion Study to Evaluate Dosimetry, Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of CEA-Pre-Targeted 212Pb Therapy in Participants With Metastatic Colorectal Cancer

This study will evaluate the dosimetry, safety, efficacy, pharmacokinetics (PK), pharmacodynamics and immunogenicity of CEA-PRIT 2.0 in participants with metas…

Metastatic Colorectal Cancer

Estimated

~$10 – $7,500

Hoffmann-La RocheNCT07416552

Observational

Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer: A Randomized Clinical Trial

The purpose of the study is to determine if an adapted mobile cognitive behavioral therapy (CBT) app (WebMAP Onc) is more effective than standard pain educatio…

Childhood Cancer SurvivorChronic Pain

Estimated

~$10 – $6,250

St. Jude Children's Research HospitalNCT07160621

Enrichment of Lung Cancer Screening Through Unexplained Weight Loss (UWL) to Stage Shift and Improve Survival

The researchers are doing this study to see if people with unexplained weight loss who have lung cancer screening are more likely to have or develop lung cance…

Lung Cancer Screening

Estimated

~$10 – $750

Memorial Sloan Kettering Cancer CenterNCT06717334

Phase 2

PReoperative Dose Escalated Stereotactic radioSurgery for Resectable Brain Metastases (PRESS)

The researchers are doing this study to see if treating people's brain tumors with stereotactic radiosurgery (SRS) before tumor resection surgery will prevent …

Brain Metastasases

Estimated

~$10 – $6,250

Memorial Sloan Kettering Cancer CenterNCT07802353

Phase 3

A Pivotal, Parallel-Arm, Phase 3, Open-Label, Active-controlled, Global, Multicenter, Randomized Basket Trial Investigating the Efficacy and Safety of Once-weekly Lonapegsomatropin Compared to Daily Somatropin in Prepubertal Children and Adolescents With Growth Failure or Short Stature Due to Growth Hormone Sufficient Disorders - Turner Syndrome, SHOX Deficiency, Small for Gestational Age, and Idiopathic Short Stature

This basket trial will enroll prepubertal children and adolescents with clinically diagnosed and genetically confirmed (if applicable) TS, SHOX-D, SGA, or ISS …

Turner SyndromeShort Stature Homeobox Gene MutationIdiopathic Short Stature+1 more

Estimated

~$10 – $8,750

Ascendis Pharma A/SNCT07221851

Phase 2

A Phase 2 Double-blind, Randomised, Placebo-controlled Trial to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of DT-101 in Adults With Major Depressive Disorder Receiving Pharmacological Therapy for Depression

In this study, researchers will learn more about a study drug called DT-101 in participants with Major Depressive Disorder (MDD), a form of depression. The goa…

Major Depressive Disorder (MDD)

Estimated

~$10 – $8,750

Draig Therapeutics LtdNCT07610473