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The Relationship Between Neurostimulation Intensity and Pupillary Dilation Reflex (PRD) in Healthy Volunteers

This a single site, observational study that will examine how the pupil responds to neurostimulation under different conditions in healthy adults. The objectiv…

Healthy Participants

Estimated

~$10 – $675

Children's National Research InstituteNCT07746167

Observational

Enhancing Weight Loss in a Digital Intervention Among Adults With Overweight or Obesity

The goal of the Reset trial is to learn about the optimal combination of dietary behavior strategies in a fully digital weight loss intervention. The intervent…

ObesityOverweightWeight Loss+2 more

Estimated

~$10 – $6,250

Stanford UniversityNCT07032571

A Prospective, Observational Pilot Study Evaluating the Performance and Clinical Acceptance of PureWick® When Used in the ICU for Urine Output Monitoring

The goal of this observational pilot study is to learn about the ability of the PureWick® Flex Female External Catheter and the PureWIck® Male External Cathete…

Urine OutputICU Patients

Estimated

~$10 – $1,125

C. R. BardNCT07744945

Phase 3

A Phase 3, Randomized, Multicenter, Double-Blind, Placebo-Controlled Study of Acoramidis for Transthyretin Amyloidosis Prevention in the Young (ACT-EARLY Trial)

Transthyretin amyloidosis (ATTR) is a disease where the normally occurring transthyretin (TTR) protein falls apart and forms amyloid, a sticky plaque-like subs…

AmyloidosisAmyloid CardiomyopathyTransthyretin Amyloidosis+3 more

Estimated

~$10 – $8,750

Eidos Therapeutics, a BridgeBio companyNCT06563895

Observational

A Pragmatic Randomized Controlled Crossover Study to Evaluate the Impact of Messaging Interventions on Emergency Department Utilization Among Oncology Patients at Parkland Health

This pragmatic randomized controlled study evaluates an education intervention designed to increase patient engagement with Oncology Acute Care (OAC) services …

Cancer

Estimated

~$10 – $6,250

University of Texas Southwestern Medical CenterNCT07550192

Observational

Telehealth Behavioral Activation for Teens

Behavioral activation is one such empirically supported intervention. Derived from cognitive-behavioral therapy, a well-established treatment for depression, b…

DepressionSuicide and Self-harmDepression in Adolescence+3 more

Estimated

~$10 – $6,250

Baylor College of MedicineNCT06273995

Observational

Evaluation of the Efficacy of Omeza® Complete Matrix in the Healing of Chronic Diabetic Foot Ulcers: A Randomized Controlled Multicenter Crossover Trial

This study aims to compare two treatment approaches for diabetic foot ulcers (DFUs): the standard of care (SOC) alone versus SOC combined with OCM. Researchers…

Diabetic Foot Ulcer

Estimated

~$10 – $8,750

Omeza, LLCNCT07161830

Phase 2

Phase 2 Study of Low Dose Tamoxifen +/- High Dose Omega-3 Fatty Acids in Overweight Postmenopausal Women at Increased Risk for Breast Cancer

This phase II trial evaluates tamoxifen, with or without omega-3 fatty acids, for reducing risk of breast cancer among postmenopausal and overweight or obese w…

Breast Atypical HyperplasiaBreast CarcinomaBreast Ductal Carcinoma In Situ+1 more

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT06195306

Observational

Oral Intake of Enteral Nutrition Formula Preceding Placement and Feeding Via G-Tube and Its Impact on Formula Intolerance in pALS

The main objective of the proposed study is to evaluate if oral intake of EN formula preceding Gtube placement will impact tolerance upon placement and feeding…

Amyotrophic Lateral SclerosisGastrointestinal IntoleranceEnteral Nutrition Therapy

Estimated

~$10 – $7,500

Andrea CharvetNCT06609213

Natural History and Phenotypic Spectrum of Sphingosine Phosphate Lyase Insufficiency Syndrome (SPLIS)

This is a prospective longitudinal natural history study with a retrospective cross-sectional arm aimed at determining the natural history of sphingosine phosp…

Sphingosine Phosphate Lyase Insufficiency Syndrome (SPLIS)

Estimated

~$10 – $675

University of California, San FranciscoNCT06669949

MAGNETIC RESONANCE SPECTROSCOPY BIOMARKERS IN TYPE 3 GAUCHER DISEASE (GD3)

Recent studies have has shown that magnetic resonance spectroscopy (MRS) can provide validated neuronal markers in patients with Type 1 GD (GD1) who are on sta…

Gaucher Disease, Type 3

Estimated

~$10 – $750

University of MinnesotaNCT05586243

Phase 3

exPDite-2: A Phase 3 Study to Assess the Efficacy and Safety of Midbrain Dopaminergic Neuronal Cell Therapy (Bemdaneprocel) for Participants With Parkinson's Disease

Study BRT-DA01-301 is a Phase 3 multicenter, randomized, sham surgery-controlled, double-blind study to assess efficacy and safety of bemdaneprocel in approxim…

Parkinsons Disease (PD)

Estimated

~$10 – $8,750

BlueRock TherapeuticsNCT06944522