Find your next paid study

Indiana UniversityNCT06982105

Phase 2

Geriatric Assessment-Guided Treatment Selection in Older Adults With Acute Myeloid Leukemia (The ALIGN-AML Trial)

This is a phase 2 randomized controlled trial to evaluate whether a geriatric assessment (GA)-guided treatment strategy reduces treatment-related toxicity and …

Acute Myeloid Leukemia

University of RochesterNCT07735208

Phase 2

A Phase I-II Study to Test the Safety and Efficacy of PD1 (AB122) and Adenosine Receptor (AB928) Antagonists With Chemotherapy After Short-Course Radiation for Rectal Cancer.

Enrolled patients will receive upfront (week 1) short-course radiotherapy to gross pelvic disease (25Gy in 5fx) in combination with AB928 (150 mg orally, once …

Rectal Cancer

Weill Medical College of Cornell UniversityNCT05024097

Phase 2

An Open-Label Study to Assess the Long-Term Safety and Tolerability of ML007C-MA in Adult Participants With Hallucinations and Delusions Associated With Alzheimer's Disease Psychosis

ML-007C-MA-222 is a 52-week, flexible-dose, open-label extension study designed to evaluate the long-term safety, tolerability, and effectiveness of ML007C-MA …

Psychosis Associated With Alzheimer's Disease

MapLight TherapeuticsNCT07459660

~$10 – $8,750

Phase 1

A Phase 1, Randomized, Investigator- and Participant-Blinded, Placebo-Controlled, Single- and Multiple-Ascending Dose Study to Characterize the Safety, Tolerability, and Pharmacokinetics of LY4515100 in Healthy Participants and an Open-Label Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics, Safety, and Tolerability of LY4515100 and of LY4515100 on the Pharmacokinetics of CYP and Transporter Substrates in Healthy Participants

The main purpose of this study is to assess the safety and tolerability of LY4515100 when given orally to healthy participants. LY4515100 will be given by itse…

Healthy

Eli Lilly and CompanyNCT07339722

~$10 – $7,500

Joint InfectionInfection of Hip Joint (Disorder)Infection of Shoulder Joint+1 more

Alpha-Defensin and Synovial Proteins to Improve Detection of Pediatric Septic Arthritis

Differentiating between septic arthritis and other causes of joint inflammation in pediatric patients is challenging and of the utmost importance because septi…

Hospital for Special Surgery, New YorkNCT03704766

Phase 3

A 52-week, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Flexible-adaptive, Group Sequential Study to Evaluate the Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease

This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, flexible-adaptive, group-sequential study (Part A), followed by an open-la…

Evaluation of a Technology-Based Parenting Intervention for Young Children Behavioral Health Challenges Identified in Pediatric Primary Care

The proposed project aims to evaluate the Parenting Young Children Check-up (PYCC) through a randomized clinical trial in a family medicine clinic in Detroit t…

Behavioral HealthDisruptive BehaviorsParenting Behavior+1 more

Wayne State UniversityNCT07734545

Exogenous Tuning of Neural Oscillations as a Mode of Treatment in Post-stroke Aphasia

This study will assess the effects of transcranial alternating current stimulation (tACS) on language recovery after stroke as well as healthy language functio…

AphasiaStroke

Medical College of WisconsinNCT04375722

Hematopoietic and Lymphatic System NeoplasmMalignant Solid Neoplasm

Journey to Understanding - American Indian Peoples Engagement in Cancer Research Arizona (JUNIPER)

This clinical trial is studying the genetic changes in cells associated with different types of cancer in American Indian (AI) populations in the Southwest to …

Mayo ClinicNCT06569316

Tele-PROTECT Therapy: Effectiveness, Empowerment, and Implementation

The purpose of this randomized trial is to conduct a fully powered effectiveness trial of video-delivered PROTECT (Tele-PROTECT) compared to a video-delivered …

DepressionElder Abuse

Weill Medical College of Cornell UniversityNCT06039930

Community Health Workers And MHealth to ImProve Viral Suppression Plus (CHAMPS+)

Although global efforts have been made to end the HIV epidemic, there are still some gaps in HIV testing, antiretroviral therapy (ART) adherence, and viral sup…

HIV/AIDS