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A Phase 1 Study Of LNK001 (Dual ENPP3/CAIX AND-gate CAR T Cell Therapy) In Advanced Or Metastatic Clear Cell Renal Cell Carcinoma

There are 2 parts to this clinical research study: Part 1 (Dose Escalation) and Part 2 (Dose Expansion). The goal of Part 1 is to find the recommended dose of…

Clear Cell Renal Cell Carcinoma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

M.D. Anderson Cancer CenterNCT07564232

Observational

A Prospective, Randomized, Multi-Center Study to Assess the Safety and Performance of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers (DBX or Grafton) Mixed With Local Autograft in Patients Undergoing One to Two-Level Instrumented Posterolateral Lumbar/Thoracolumbar Fusion (PLF)

This is a phase IV post-marketing study for MagnetOs Easypack Putty. MagnetOs Easypack Putty is a synthetic bone graft extender product that is routinely used …

Degenerative Disc DiseaseSpine FusionBack Pain

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Kuros Biosurgery AGNCT04679844

Phase 2

TAGGED: A Phase 2 Study Using Low Dose/Metronomic Trabectedin, Gemcitabine, and Dacarbazine as 2nd/3rd/4th Line Therapy for Advanced Soft Tissue Sarcoma

This is an open label phase 2 study using metronomic doses of trabectedin, gemcitabine and dacarbazine given intravenously.

Leiomyosarcoma

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Sarcoma Oncology Research Center, LLCNCT04535271

Phase 2

A Phase 2, Open-label, Multicenter, Single-arm Trial of JNJ-101556143, an Androgen Receptor-targeted Regulated Induced Proximity Targeting Chimera (RIPTAC™) Therapeutic in Participants With Metastatic Androgen Pathway Modulation-Resistant Prostate Cancer

The purpose of this study is to evaluate how well JNJ-101556143 works in participants with metastatic androgen pathway modulation-resistant prostate cancer (mA…

Prostatic Neoplasms

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Janssen Research & Development, LLCNCT07832292

Observational

Hybrid Type I Trial of a Peer-Led Court Navigation Program to Improve Substance Use Disorder Treatment Receipt and Reduce Overdose and Incarceration Among People Passing Through Courthouses

This project is a hybrid type I clinical trial to assess the effectiveness and implementation determinants of a peer-led court navigation program for people wh…

Substance Use Disorder (SUD)

Estimated

~$10 – $1,125

Actual pay is set by the research site.

RTI InternationalNCT07700407

Phase 4

Long-term Follow-up Study for Participants Previously Treated With Ciltacabtagene Autoleucel

The purpose of this study is to collect long-term follow-up data on delayed adverse events after administration of ciltacabtagene autoleucel (cilta-cel), and t…

Multiple Myeloma

Estimated

~$25 – $1,400

Actual pay is set by the research site.

Janssen Research & Development, LLCNCT05201781

Phase 1

A Phase 1, Open-Label, Non-randomized, Single Dose, Safety, Tolerability, and Pharmacokinetic Study of Vorasidenib Administered to Participants With Severe Hepatic Impairment and Matched-Participants With Normal Hepatic Function

The objective of this study is to evaluate the pharmacokinetics, safety, and tolerability of one dose of vorasidenib in participants with severe impaired hepat…

Severe Hepatic ImpairmentNormal Hepatic Function

Estimated

~$500 – $11,250

Actual pay is set by the research site.

Institut de Recherches Internationales Servier (I.R.I.S.)NCT07250633

Phase 1

A Phase 1 and Randomized Phase 2 Trial of Selinexor and Temozolomide in Recurrent Glioblastoma

This phase I/II trial tests the safety, side effects and best dose of selinexor given in combination with the usual chemotherapy (temozolomide) and compares th…

Recurrent Glioblastoma, IDH-WildtypeRecurrent MGMT-Methylated Glioblastoma

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT05432804

Observational

Offering Routine and Rapid Point of Care (POC) Syphilis Testing in Pregnant Patients Presenting to the Emergency Department

The purpose of this study is to offer routine lab-based and rapid point of care (POC) syphilis diagnostic testing in the emergency department (ED) and obstetri…

Syphilis

Estimated

~$10 – $750

Actual pay is set by the research site.

The University of Texas Health Science Center, HoustonNCT06645106

Observational

Collaborative Care Intervention for Cancer Patients and Their Family Caregivers -LITE

To test the efficacy of a web-based stepped collaborative care intervention to reduce symptoms of depression, pain, and fatigue and improve health-related qual…

CancerDepressionFatigue+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of PittsburghNCT05601206

Phase 1

A Three-Part, Phase 1/2a, Randomized, Double-blind, Placebo-Controlled, Single and Multiple Dose Study of the Safety, Tolerability, and Pharmacokinetics of ALN-PNP, an siRNA Targeting PNPLA3, in Healthy Adults and Adult Participants With MASLD

This study is researching an experimental drug called ALN-PNP (called "study drug"). This is a first in human study. The study drug is not approved by any publ…

Healthy VolunteersMetabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Regeneron PharmaceuticalsNCT05648214

Developing and Refining an Intervention to Assess and Address Health-Related Social Needs Among Families of Children With Cancer

The purpose of this study is to design Community Enhancing Resources for Childhood cAncer support (CERCA) and refine intervention procedures to target Health-r…

Childhood CancersCaregiver Social SupportCaregiver Distress+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Wake Forest University Health SciencesNCT07278414