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25,415 recruiting studies available now

A Phase 1/2, Open-label Study of Oral S241656 (BDTX-4933) as Monotherapy and in Combination With Other Anti-Cancer Therapies in Patients With KRAS, BRAF and Other Selected RAS/MAPK Mutation-Positive Malignancies

BDTX-4933-101 is a first-in-human, open-label, Phase 1/2 dose escalation, dose optimization and expansion study designed to evaluate the safety and tolerabilit…

Non-small Cell Lung CancerHistiocytic NeoplasmHistiocytosis+29 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Institut de Recherches Internationales ServierNCT05786924

Phase 1

A First-In-Human, Phase 1 a/b Dose Escalation and Expansion Study to Evaluate RBS2418 as Monotherapy and in Combination With Pembrolizumab in Subjects With Advanced Unresectable, Recurrent or Metastatic Tumors

RBS2418 (investigational product) is a specific immune modulator, working through ectonucleotide pyrophosphatase/phosphodiesterase I (ENPP1), designed to lead …

Advanced Cancer

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Riboscience, LLC.NCT05270213

Phase 3

A Prospective, Open-label, Multicenter, Randomized Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Renal Allograft Recipients Aged 12 to Less Than 18 Years of Age to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications

The purpose of this study is to evaluate the benefits and risks of conversion of existing adolescent kidney allograft recipients aged 12 to less than 18 years …

Renal Allograft Recipients

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Bristol-Myers SquibbNCT04877288

An Observational Study in Patients With Indolent Systemic Mastocytosis

This is a Phase 4, non-interventional, observational study to collect detailed data on the clinical characteristics, clinical outcomes and medical management o…

Indolent Systemic Mastocytosis

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Blueprint Medicines CorporationNCT07264959

Phase 2

Restoration of Hypoglycemia Awareness With Metoclopramide

Metoclopramide is a drug approved by the FDA for gastroesophageal reflux and to relieve symptoms in adults with acute and recurrent diabetic gastroparesis. The…

Hypoglycemia Unawareness

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Simon FisherNCT03970720

Observational

A Pilot Randomized Waitlist-Controlled Study of Home-Based Rhythmic Auditory Stimulation to Evaluate Mobility, Balance, and Patient-Reported Outcomes After Traumatic Brain Injury

The goal of this study is to learn whether a home-based rhythmic auditory stimulation (RAS) program using the MR-001 device can help improve walking, balance, …

Traumatic Brain InjuryTraumatic Brain Injury | PatientTBI+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Craig HospitalNCT07702513

Observational

The PEARL Trial: A Randomized Trial of Amnioinfusion's Protective Effects on Respiratory and Longitudinal Pediatric Outcomes After Intrapartum Thick Meconium Exposure

Thick meconium in the amniotic fluid occurs in about one out of seven pregnancies and increases the chance that a newborn may have breathing problems after bir…

Neonatal Respiratory Distress Related ConditionsMeconiumPerinatal Morbidity+10 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Medical College of WisconsinNCT07274527

Observational

Dose-Escalated Spine SbRT (DESSRT) for Localized Metastasis to the Spinal Column

This study is being done to determine the feasibility and tolerability of a novel regimen of spine stereotactic radiosurgery (SSRS). SSRS delivers high doses o…

Spine MetastasesMetastasis Spine

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Baptist Health South FloridaNCT04802603

Phase 2

Control Systems Engineering to Address the Problem of Weight Loss Maintenance: A System Identification Experiment to Model Behavioral & Psychosocial Factors Measured by Ecological Momentary Assessment

This project capitalizes on principles of control systems engineering to build a dynamical model that predicts weight change during weight loss maintenance usi…

Overweight and Obesity

Estimated

~$75 – $2,000

Actual pay is set by the research site.

The Miriam HospitalNCT06244888

Pilot Proof of Concept Study of miRNA and Protein Signatures in Exosomes From Blood and Cystic Fluid in Patients Undergoing Surgery for Worrisome Pancreatic Cysts

The goal of this study is to collect biospecimens (blood and cystic fluid) and data from participants who have a pancreatic cyst that requires surgical resecti…

Pancreatic Cyst

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Translational Genomics Research InstituteNCT07767227

Phase 1

A Phase 1/2, Multicenter, Open-Label, Dose-Escalation, Safety, Tolerability, and Clinical Activity Study of a Single Dose of JAG201 Gene Therapy Delivered Via Intracerebroventricular Administration in Participants With SHANK3 Haploinsufficiency

This is a Phase 1/2, first in human, open-label, dose-escalation study to evaluate the safety, tolerability, and clinical activity of a single dose of JAG201 a…

SHANK3 HaploinsufficiencyPhelan-McDermid Syndrome

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Jaguar Gene Therapy, LLCNCT06662188

Observational

Exercise-induced Steroid Changes in Active Surveillance for Prostate Cancer

The purpose of this research study is to understand how a short session of a home-based bodyweight high-intensity interval training (HIIT) affects steroid horm…

Prostate Cancer

Estimated

~$10 – $750

Actual pay is set by the research site.

University of MiamiNCT07518888