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27,292 recruiting studies available now

Merging Strategy That Uses Gut Microbiome Profiling and Targeted Modulation to Improve CAR-T Cell Therapy Outcomes, Predict Responses, and Reduce Toxicity

Chimeric Antigen Receptor T-Cell (CAR-T) therapy has transformed the management of large B-cell lymphoma, and multiple myeloma by achieving remarkable response…

Lymphoma, B-CellMultiple Myeloma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of ChicagoNCT07871747

Observational

Augmenting Cognitive-behavioral Therapy With rTMS of the Medial Prefrontal and Anterior Cingulate Cortices for the Treatment of Cocaine Use Disorder

The goal of the study is to investigate the feasibility, safety, and effect of rTMS on mPFC/dACC activity using a combination of fMRI and clinical outcome meas…

Cocaine UseCocaine DependenceCocaine Use Disorder+2 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

New York State Psychiatric InstituteNCT05974202

Ex-Vivo Trial of En-bloc Transurethral Resection of Bladder Tumor (En-bloc TURBT) Specimens Using a Redesigned Surgical Resectoscope Device

Background: Bladder cancer is the sixth most common cancer in the United States. The way that doctors remove tumors in bladder surgeries may leave some cancer…

Bladder Cancer

Estimated

~$10 – $675

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT04235764

Observational

Feasibility and Preliminary Effectiveness of HABIT-ILE + Functional Strength Training in Children With Spinal Muscular Atrophy (SMA): a Prospective Single-group Intervention Trial.

This single-arm pilot study will assess the preliminary effectiveness of an intensive motor skill intervention (HABIT-ILE) combined with functional strength tr…

Spinal Muscular Atrophy (SMA)

Estimated

~$10 – $750

Actual pay is set by the research site.

Teachers College, Columbia UniversityNCT07488338

Phase 3

COVE-4: A Phase 3, Open-Label, Long-Term Follow-Up Study to Evaluate the Safety and Efficacy of YCANTH (VP-102/TO-208) in Subjects With Common Warts (Verruca Vulgaris)

People who participated in either the COVE-2 or COVE-3 study for common warts, may be eligible to enroll into this Long Term Follow Up (LTFU) study COVE-4. The…

Common Warts (Verruca Vulgaris)Common WartsHuman Papilloma Virus (HPV)+1 more

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Verrica Pharmaceuticals Inc.NCT07457918

Effect of Thickened Feeds on Clinical Outcomes in Children With Brief Resolved Unexplained Event

This observational study will examine the effects of thickened feeds on clinical outcomes and healthcare utilization in infants with brief resolved unexplained…

Brief Resolved Unexplained EventApparent Life Threatening EventOropharyngeal Dysphagia

Estimated

~$10 – $750

Actual pay is set by the research site.

Boston Children's HospitalNCT04477460

Phase 1

A First-In-Human Clinical Trial of Lentiviral-mediated CSF2RA Gene Transfer/Pulmonary Macrophage Transplantation Therapy of Hereditary Pulmonary Alveolar Proteinosis

The major goal of this study is to evaluate a new type of cell transplantation therapy for individuals with hereditary PAP, study a new treatment that may be u…

Hereditary Pulmonary Alveolar Proteinosis

Estimated

~$150 – $2,700

Actual pay is set by the research site.

Children's Hospital Medical Center, CincinnatiNCT05761899

Phase 1

Efficacy of Booster Injection With Gardasil-9 Vaccine on Intersurgical Interval (ISI) for Adults With Recurrent Respiratory Papillomatosis (RRP)

The investigators propose the study titled "Efficacy of booster injection with Gardasil-9 vaccine on intersurgical interval (ISI) for adults with recurrent res…

Recurrent Respiratory Papillomatosis (RRP)

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Ohio State UniversityNCT07339163

Phase 2

Vonescimab for the Treatment of Previously Treated Advanced or Unresectable Leiomyosarcoma - a Phase II Trial

The purpose of this study is to find out if Ivonescimab is an effective and safe treatment that causes few or mild side effects for people with advanced/unrese…

Leiomyosarcoma

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Memorial Sloan Kettering Cancer CenterNCT07516925

Phase 2

A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of INCB000928 in Participants With Fibrodysplasia Ossificans Progressiva

This Phase 2, Randomized, Double-Blind, Placebo-Controlled Study is intended to evaluate the Efficacy, Safety, and Tolerability and PK of INCB000928 administer…

Fibrodysplasia Ossificans Progressiva (FOP)

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Incyte CorporationNCT05090891

Observational

The VENTOR Clinical Study - VENTilation and Airway Optimization for Cardiac Arrest Resuscitation

To evaluate the initial safety and effectiveness of the Ventor Airway System in providing short-term ventilation support in non-breathing subjects during cardi…

Cardiac Arrest (CA)

Estimated

~$10 – $1,125

Actual pay is set by the research site.

CoLabs MedicalNCT06759389

Pulmonary Hypertension (PH) Biorepository for Translational Research

Background: Pulmonary hypertension (PH) is high blood pressure in the blood vessels of the lungs. It can lead to heart failure and death if not treated. Resea…

Pulmonary Hypertension

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institutes of Health Clinical Center (CC)NCT07647549