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Response of Bony Metastasis to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancers With Actionable Driver Mutations

The purpose of this study is to assess percentage reduction in the of urine NTX and serum CTX , in patients with NSCLC and bone metastases 1) with actionable d…

Carcinoma, Non-Small-Cell Lung

Estimated

Pay not disclosed — ask the coordinator

University of Colorado, DenverNCT03958565

Phase 1

Open Label Phase 1 and Target Validation Study of ONC206 in Children and Young Adults With Newly Diagnosed or Recurrent Diffuse Midline Glioma (DMG), and Other Recurrent Primary Malignant Central Nervous System (CNS) Tumors

This phase I trial studies the effects and best dose of ONC206 alone or in combination with radiation therapy in treating patients with diffuse midline gliomas…

Diffuse Midline Glioma (DMG)GlioblastomaRecurrent Ependymoma+5 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Sabine Mueller, MD, PhDNCT04732065

Observational

Randomized Trial of Cold EMR Compared to Hybrid Cold EMR.

The goal of this randomized clinical trial is to learn if a combination of hot and cold EMR technique is associated with a lower risk of polyp recurrence witho…

Polyp of ColonEndoscopic Mucosal Resection

Estimated

~$10 – $750

Actual pay is set by the research site.

The Cleveland ClinicNCT06937671

Phase 3

A Phase 3, Single-Arm, Open-Label, Long-Term Extension Study To Evaluate The Safety And Efficacy Of Enpatoran In Participants With Active Cutaneous Manifestations Of Lupus Erythematosus With Or Without Systemic Disease Receiving Standard Of Care [Elowen-LTE]

The purpose of this study is to evaluate the long-term safety and efficacy of orally administered enpatoran in participants with cutaneous manifestations of lu…

Systemic Lupus Erythematosus (SLE)Cutaneous Lupus Erythematosus (CLE)

Estimated

~$50 – $2,100

Actual pay is set by the research site.

EMD Serono Research & Development Institute, Inc.NCT07840287

Improving Survival for Those With Metastatic Lobular Breast Cancer Through Development of the Multi-center PLUMB Registry-a Prospective Study of LobUlar Metastatic Breast Cancer

This is a prospective observational registry for patients with invasive lobular carcinoma (ILC) of the breast. After the first 1cohort is enrolled, the collect…

Metastatic Breast CancerLobular Breast Carcinoma

Estimated

~$10 – $675

Actual pay is set by the research site.

University of California, San FranciscoNCT05964504

Phase 2

Neostigmine and Glycopyrrolate for the Treatment of Post Dural Puncture Headache After Known Dural Puncture With a Tuohy Needle: A Pilot Study

The purpose of this study is to evaluate Neostigmine and Glycopyrrolate to treat post-dural puncture headache (PDPH) to reduce the proportion of postpartum wom…

Post-Dural Puncture Headache

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Mayo ClinicNCT05116930

Observational

Controlled Arterial Protection to Ultimately Remove Embolic Material

The objective of this study is to demonstrate safety and efficacy of the EmStop Embolic Protection System when used as indicated to capture and remove thrombus…

Aortic Valve StenosisAortic StenosisAortic Valve Disease

Estimated

~$10 – $1,050

Actual pay is set by the research site.

EmStop IncNCT07276711

Observational

Non-Nutritive Sweeteners, Glucose Homeostasis, and the Gut Microbiome in Prediabetes

This pilot study will evaluate the feasibility and acceptability of a 30-day sucralose intervention among adults with prediabetes. Participants will consume si…

Prediabetes

Estimated

~$10 – $750

Actual pay is set by the research site.

Tufts UniversityNCT07868432

Observational

Clinical Performance Evaluation of Two Monthly Replacement Silicone Hydrogel Multifocal Toric Lens Designs in Habitual Soft Contact Lens Wearers

To compare the performance of two leading soft multifocal Toric contact lenses.

AstigmatismMyopia

Estimated

~$10 – $1,050

Actual pay is set by the research site.

CooperVision International Limited (CVIL)NCT07829419

Phase 4

Effects of NAD Restoration on Neurovascular Coupling in Community Dwelling Older Adults

Daily consumption of one of the forms of Vitamin B3, the Nicotinamide Riboside (NR), energizes the body and combats cellular aging. This study is designed to t…

Aging

Estimated

~$25 – $1,000

Actual pay is set by the research site.

University of OklahomaNCT05483465

Phase 2

An Extension Study to Evaluate the Long-term Safety and Efficacy of Afimkibart (RO7790121) in Patients With Rheumatoid Arthritis Who Participated in Previous Afimkibart Clinical Trials

The study will evaluate the long-term safety and efficacy of Afimkibart (also known as RO7790121) in participants with moderate to severe Rheumatoid Arthritis …

Rheumatoid Arthritis

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Hoffmann-La RocheNCT07620392

Outcome Reflection for Immune Mediated Rejection by Utilizing Artificial Intelligence in Cardiac Transplant Patients Through Early and Late Echocardiographic Analysis (ORACLE)

The purpose of this research is to detect episodes of rejection versus non-rejection after cardiac transplant and the diagnostic accuracy of an Artificial Inte…

Cardiac Transplant Rejection

Estimated

~$10 – $750

Actual pay is set by the research site.

Mayo ClinicNCT06178744