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27,293 recruiting studies available now

A Pilot Study in the Treatment of Refractory Adenovirus (ADV) Infection With Related Donor ADV Cytotoxic T-Lymphocytes (ADV-CTLs)in Children, Adolescents and Young Adult Recipients

Related donor Adenovirus (ADV) specific cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered …

AdenovirusPrimary Immune Deficiency Disorder

Estimated

~$75 – $2,000

Actual pay is set by the research site.

New York Medical CollegeNCT03266627

Observational

Activity Post Spinal Surgery Engagement Trial

Back pain can be disabling, limiting the ability to walk and to engage in physical activity. For patients with degenerative lumbar spinal stenosis, decompressi…

Spinal Surgery for Lumbar Spinal Stenosis (LSS)

Documented

Up to $645

Brigham and Women's HospitalNCT07825480

Natural History of Post-Coronavirus Disease 19 Convalescence at the National Institutes of Health

Background: People who get COVID-19 have a wide range of symptoms. They also recover from COVID-19 in different ways. In this study, researchers will use surv…

Post-Coronavirus Disease 19

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Neurological Disorders and Stroke (NINDS)NCT04573062

Phase 1

A Phase I Dose-escalation Study of Preoperative Radiation Therapy in Participants With Resectable Recurrent Abdominal Adrenocortical Carcinoma

Background: Adrenocortical carcinoma (ACC) is a rare cancer of the adrenal glands. ACC often returns after tumors are removed with surgery. Less than 35% of p…

Adrenocortical Carcinoma (ACC)Recurrent Adrenocortical Carcinoma (ACC)Recurrent Abdominal Adrenocortical Carcinoma (ACC)+2 more

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT06487481

Phase 1

Open-label, Non-randomized, Multi-cohort, Phase 1b/2 Trial Investigating the Safety, Tolerability, and Antitumor Activity of STC-15 (a METTL3 Inhibitor) as a Part of Combination Therapy With Toripalimab in Participants With Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas

This early phase oncology trial will be conducted at various study centers to investigate the safety, tolerability, and antitumor activity of STC-15 (a METTL3 …

Solid TumorSarcomaLeiomyosarcoma+1 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

STORM Therapeutics LTDNCT06975293

Observational

EDEN Intracardiac Electrogram Recording and Classifying System

Background: Heart surgeons use electrocardiogram (ECG) machines to record electrical signals from the heart during procedures. Normal ECG machines connect onl…

Ventricular Arrhythmia

Estimated

~$10 – $675

Actual pay is set by the research site.

National Heart, Lung, and Blood Institute (NHLBI)NCT07137455

Phase 4

Open Label, Multi-center Roll-over Study to Assess Long Term Safety in Patients Who Have Completed a Global Novartis or GSK Sponsored Dabrafenib and/or Trametinib Study

This study is to provide access for patients who are receiving treatment with dabrafenib and/or trametinib in a Novartis-sponsored Oncology Global Development,…

MelanomaNon Small Cell Lung CancerSolid Tumor+2 more

Estimated

~$25 – $1,400

Actual pay is set by the research site.

Novartis PharmaceuticalsNCT03340506

NIAID Centralized Sequencing Protocol

Background: Genetic testing called "sequencing" helps researchers look at DNA. Genes are made of DNA and are the instructions for our bodies to function. We a…

AtopyPrimary ImmunodeficiencyAutoimmunity+1 more

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Allergy and Infectious Diseases (NIAID)NCT03206099

Phase 2

Safety and Efficacy of OTL78, a PSMA-targeted Fluorescent Agent, for Intraoperative Imaging of Prostate Cancer: A Phase IIb Trial Randomized Trial

This is a trial to assess the accuracy of an imaging agent, PSMA targeted fluorescent dye OTL78 (zopocianine), in combination with Near InfraRed (NIR) fluoresc…

Prostate Cancer SurgeryProstate Cancer Metastatic Disease

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Clinton BahlerNCT07725523

Observational

A Multicenter Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-Cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymphoblastic Leukemia

Background: Chimeric antigen receptor T-cell (CART) therapy is a form of immunotherapy which can be used to treat people with relapsed B-ALL. For those who ac…

B-AllAcute Lymphoblastic Leukemia

Estimated

~$10 – $675

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT05621291

Phase 3

A Phase 3, Multicenter, Randomized, Open-label Trial of Trastuzumab Deruxtecan in Combination With Pembrolizumab Versus Platinum-based Chemotherapy in Combination With Pembrolizumab, as First-line Therapy in Participants With Locally Advanced Unresectable or Metastatic HER2 Overexpressing and PD-L1 TPS <50% Non-squamous Non-small Cell Lung Cancer (DESTINY-Lung06)

This clinical trial is designed to assess the efficacy and safety of trastuzumab deruxtecan (T-DXd; Enhertu®) in combination with pembrolizumab versus platinum…

Non-small Cell Lung Cancer

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Daiichi SankyoNCT06899126

Botulinum Toxin for the Treatment of Neurological Disorders

BTX has been used since the 1980s in support of the research mission of NINDS. Initial studies were focused on expanding the applicability of BTX treatment to …

Movement Disorders

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Neurological Disorders and Stroke (NINDS)NCT00001208