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Randomized Controlled Trial Comparing Clinical Outcomes of Patients Treated Surgically With Suture Button Versus Fibulink Fixation for Acute Ankle Syndesmosis Injuries

This project consists of a randomized controlled study design. Study candidates will include all patients 18 years or older, who were evaluated at UCSD and fou…

Ankle InjuriesSyndesmotic InjuriesAnkle Fractures

Estimated

~$10 – $750

Actual pay is set by the research site.

University of California, San DiegoNCT05729542

Phase 1

A Combined Single and Multiple Ascending Dose Phase 1a/1b, Double-blind, Placebo-Controlled, and Food-effect Study to Evaluate the Safety and Pharmacokinetics of Oral KM-023 in Healthy Participants. Followed by a 3-month Open Label Study to Evaluate the Safety, Pharmacokinetics and Efficacy of Oral KM-023 in Olmsted Syndrome Patients

The trial is conducted in order to assess the safety of KM-023 and to observe what effects, both beneficial and adverse, it has on the body, and the way the bo…

Olmsted Syndrome

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Orvida Pharma (formerly Kamari Pharma)NCT07090889

A Sub-registry to Observe the Effect of Alglucosidase Alfa or Avalglucosidase Alfa Treatment on Pregnancy and Infant Growth in Women With Pompe Disease

This Sub-registry is a multicenter, international, longitudinal, observational, and voluntary program designed to track pregnancy outcomes for any pregnant wom…

Glycogen Storage Disease Type II (GSD-II)Pompe Disease (Late-onset)Glycogenesis 2 Acid Maltase Deficiency

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Genzyme, a Sanofi CompanyNCT00567073

Phase 1

Intra-nasal Ketorolac Versus Oral Diclofenac for Acute Ureteral Stent-associated Pain Following Ureteroscopy for Stone Disease

Objective: To improve quality-of-life and health care delivery to patients receiving ureteral stents. Specific Aims: Evaluate the feasibility, practicality, a…

Post Operative PainUrolithiasisUreter Calculi+1 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of Texas Southwestern Medical CenterNCT06158620

Phase 1

Clinical Trial of CD40L-augmented Tumor Infiltrating Lymphocytes (CD40L TIL) for Patients With Oncogene-Driven Advanced Non-Small Cell Lung Cancer (NSCLC)

To determine the effect of a special preparation of cells, called tumor-infiltrating lymphocytes (TIL) stimulated with CD40L, when given with the drug nivoluma…

Non Small Cell Lung CancerStage IV Non-small Cell Lung CancerRecurrent Non Small Cell Lung Cancer

Estimated

~$150 – $3,000

Actual pay is set by the research site.

H. Lee Moffitt Cancer Center and Research InstituteNCT05681780

Phase 2

Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases

This study will assess the safety, efficacy, and feasibility of ⍺/β CD3+ T-cell and CD19+ B-cell depletion in allogeneic stem cell transplantation in patients …

Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaJuvenile Myelomonocytic Leukemia+4 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University of FloridaNCT05800210

Observing the Acute Effects Following a Single Oral Dose of Kratom and Effects Following Kratom Cessation Among Adults Who Use Regularly.

The goal of this observational clinical study is to is to learn more about how commercial kratom products affect healthy adults who consume them regularly. The…

Kratom PharmacokineticsKratom PharmacodynamicsKratom

Estimated

~$10 – $750

Actual pay is set by the research site.

Johns Hopkins UniversityNCT06089980

Observational

MC250406 Feasibility Study: Automated Risk Stratification, Serial AI-Augmented Imaging, and Biobanking for Early Detection of Sporadic Pancreatic Cancer (AI-PACED)

This clinical trial studies a new screening program to improve the early detection of sporadic pancreatic cancer in individuals with a high risk of developing …

Pancreatic Ductal Adenocarcinoma

Estimated

~$10 – $750

Actual pay is set by the research site.

Mayo ClinicNCT07324096

Observational

A Multilevel, Multiphase Optimization Strategy for PrEP: Patients and Providers in Primary Care

What is known: There are 1.2 million people in the US who meet the indications for PrEP; yet, disparities exist in uptake. For example, only 9% of Black and 16…

HIV Seropositivity

Estimated

~$10 – $750

Actual pay is set by the research site.

Henry Ford Health SystemNCT06334341

Phase 2

A Multicenter, Single Arm, Open Label Biopsy Study to Evaluate Structural and Functional Changes in Kidneys of Adult Patients With IgA Nephropathy Receiving Iptacopan on Top of Supportive Care

A study to investigate the impact of iptacopan treatment on the underlying immunopathology in patients with IgAN by assessing changes in key clinical and molec…

Glomerulonephritis, IGAImmunoglobulin A Nephropathy

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Novartis PharmaceuticalsNCT06797518

Phase 3

ROSETTA Lung-201: A Randomized, Multicenter, Open-label Phase 3 Study of Pumitamig Monotherapy Compared to Durvalumab in Participants With Unresectable Stage III NSCLC Without Progression After Platinum-based Concurrent Chemoradiation Therapy.

A study to evaluate Pumitamig versus Durvalumab following concurrent chemoradiation therapy in participants with unresectable stage III Non-small Cell Lung Can…

Non-small Cell Lung Cancer (NSCLC)

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Bristol-Myers SquibbNCT07361497

Observational

A Multi-Site Feasibility Trial of Embedded Emergency Department Physical Therapy for Dizziness

This is a multi-site feasibility trial of an embedded emergency department (ED) physical therapy care model for dizziness at two EDs in the Northwestern Medici…

Dizziness

Estimated

~$10 – $750

Actual pay is set by the research site.

Northwestern UniversityNCT07225023