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A Phase 1, Multicenter, Open-Label, Dose-Escalation Study to Assess Safety, Tolerability, and Efficacy of EXS74539 as Monotherapy in Participants With Select Solid Tumors

The primary purpose of this study is to determine the safety, tolerability, and maximum tolerated dose (MTD) of EXS74539 (REC-4539) in participants with select…

Solid TumorSmall Cell Lung Cancer (SCLC)High Grade Neuroendocrine Cancer+9 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc.NCT07517198

GBE Deficiency (GSD IV and APBD) Natural History Study

Collection and review of clinical information related to glycogen branching enzyme (GBE) deficiency, diagnosed as Glycogen Storage Disease Type IV (GSD IV) or …

Glycogen Storage Disease Type IVAdult Polyglucosan Body DiseaseGSD4+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Duke UniversityNCT02683512

Phase 1

A Phase I/Ⅱa Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Preliminary Efficacy of HMPL-A830 in Solid Tumors

This is a first-in-human (FIH), multicenter, open-label, phase I/Ⅱa clinical study of HMPL-A830 in participants with histologically or cytologically confirmed,…

Solid Tumor, Adult

Estimated

~$150 – $4,500

Actual pay is set by the research site.

HutchmedNCT07718581

Observational

Personalized Toolkit Building a Comprehensive Approach to Resource Optimization and Empowerment in Pregnancy & Beyond (PTBCARE+) A Randomized Controlled Trial (RCT) of Personalized Care for Prenatal Stress Reduction and Preterm Birth Disparities Prevention

The goal of this clinical trial is to learn if a personalized prenatal support program \[(Personalized Toolkit Building a Comprehensive Approach to Resource op…

Preterm Birth ComplicationPreterm BirthPreterm Birth Recurrence+19 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Gender Disparities in Voice Outcomes After Tracheoesophageal Puncture in Total Laryngectomy

To perform a multi-site prospective study assessing, both subjectively and objectively, the gender disparities in speech outcomes of patients using TEP after t…

Speech DisordersSpeech DysfunctionLaryngectomy; Status+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of California, DavisNCT05489965

EEG Dynamics in Lennox-Gastaut Syndrome Patients Undergoing Fenfluramine Treatment

This study plans to learn if certain markers found during electroencephalogram (EEG) analysis could predict fenfluramine responsiveness to give clinicians grea…

Lennox Gastaut Syndrome (LGS)

Estimated

~$10 – $750

Actual pay is set by the research site.

University of ChicagoNCT07555171

Phase 2

A Phase 2 Study of Emavusertib in Combination With an Approved Bruton Tyrosine Kinase Inhibitor in Patients With Chronic Lymphocytic Leukemia and Other B-cell Malignancies

The primary objective of the study for Cohort 1 and Cohort 2 is to assess the anticancer activity of emavusertib in combination with zanubrutinib in participan…

Chronic Lymphocytic LeukemiaB-cell Malignancies

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Curis, Inc.NCT07271667

Phase 3

Efficacy and Implementation of Exercise-based Smoking Cessation Treatment for Adults With High Anxiety Sensitivity.

Anxiety sensitivity, reflecting the fear of bodily sensations, is a risk factor for the maintenance and relapse of smoking. This study is designed to address t…

Nicotine Dependence

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Jasper A. SmitsNCT06053567

Observational

Adaptive Multi-tiered School-based Prevention to Promote Youth Mental Health and Create Equitable and Sustainable Systems of Care

The goal of this clinical trial is to learn if two behavioral interventions work to reduce office disciplinary referrals, improve attendance, and reduce depres…

School AttendanceSchool ClimateSchool Engagement+7 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of OregonNCT07264621

Observational

The Effect of Repetitive Trans-cranial Magnetic (rTMS) Stimulation on Abnormal Cortical Hubs Identified by Functional Magnetic Resonance in Subjects With Dystonia

By tracking resting-state fMRI scans, we aim to discover how repetitive transcranial magnetic stimulation (rTMS) changes brain connectivity in individuals with…

Dystonia Disorder

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Northwell HealthNCT07626216

Phase 2

A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effects of Intranasal Oxytocin in Adults With Binge-eating Disorder

This study evaluates the impact of intranasal oxytocin vs placebo in patients with binge eating disorder or episodes of binging. We hypothesize that 8 weeks of…

Binge-eating Disorder

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Massachusetts General HospitalNCT05664516

Sanford Population Level Estimation of Type 1 Diabetes Risk GEnes in Children

In partnership with Helmsley Charitable Trust, the Sanford PLEDGE Study is a large-scale, observational, feasibility study of general population screening for …

Type 1 DiabetesCeliac Disease

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Sanford HealthNCT04477928