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27,354 recruiting studies available now

Development of a cfDNA 5mC/5hmC-based Epigenetic Biomarker Panel to Identify Determinants of Response In VEGF/EGFR-targeted Therapy for Metastatic Colorectal Cancer

The EpiDRIVE study aims to identify cfDNA-based epigenetic determinants of response in metastatic colorectal cancer (mCRC) patients treated with EGFR- or VEGF-…

CRC (Colorectal Cancer)

Estimated

~$10 – $750

Actual pay is set by the research site.

City of Hope Medical CenterNCT07224841

Phase 3

Investigating the Impact of GLP-1 RA Therapy on Osteosarcopenia in Older Female Adults With Diabetes

The goal of this study is to learn how GLP-1 receptor agonist therapy affects muscle and bone health in older females over age 65 with type 2 diabetes. The ma…

Diabetes Mellitus, Type 2

Estimated

~$50 – $1,500

Actual pay is set by the research site.

Emory UniversityNCT07428746

Segmental Substrate Isolation for the Treatment of Ventricular Tachycardia in Patients With Structural Heart Disease

The goal of this study is to map conducting channels within scar that cause ventricular tachycardia (VT) in patients with scar in their hearts in order to bloc…

Ventricular Tachycardia (VT)Ischemic CardiomyopathyNonischemic Cardiomyopathy

Estimated

~$10 – $750

Actual pay is set by the research site.

New York Medical CollegeNCT07814079

An Open Label, Multi-Center, Single Arm Prospective Evaluation of Exactech Vantage Total Ankle System

The objectives of this study are to evaluate the performance and safety of the Vantage Total Ankle System. This study will follow subjects for a period of up t…

Ankle Rheumatoid ArthritisArthritis of AnkleFailure, Prosthesis

Estimated

~$10 – $1,125

Actual pay is set by the research site.

ExactechNCT05619588

Phase 1

A Phase 1, Open-label, Single-arm Study of APR 2020 in Transfusion Dependent, Steroid Resistant Pediatric and Adolescent Subjects With RPS19 Deficient Diamond Blackfan Anemia by Transplantation of Autologous CD34+ Stem Cells Transduced With CLIN LV EFS coRPS19 PRE* (APR-2020)

Brief summary The goal of this clinical trial is to learn if APR-2020 is safe and can help treat Diamond-Blackfan Anemia (DBA) in adolescents and children. Th…

RPS19 Deficient Diamond-Blackfan Anemia

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Apriligen, Inc.NCT07476183

Phase 1

A Phase 1/2 Dose-Escalation and Randomized, Controlled, Masked Expansion Trial of Intravitreal 4D-150 Gene Therapy in Adults With Neovascular (Wet) Age-Related Macular Degeneration

Phase 1/2 dose-escalation and randomized, controlled, masked expansion trial in adults with wet AMD undergoing active anti-VEGF treatment. Substudies will eva…

Neovascular (Wet) Age-Related Macular Degeneration

Estimated

~$150 – $4,200

Actual pay is set by the research site.

4D Molecular TherapeuticsNCT05197270

Phase 2

An Open-Label Multi-Center Phase II Study of Neoadjuvant Atezolizumab-Based Combination Therapy in Men With Localized Prostate Cancer Prior to Radical Prostatectomy

This phase II trial studies how well atezolizumab works alone or in combination with etrumadenant or tocilizumab in treating men with localized prostate cancer…

Prostate AdenocarcinomaProstate CancerLocalized Prostate Cancer

Estimated

~$75 – $3,000

Actual pay is set by the research site.

David OhNCT03821246

Observational

Enhancing Cognitive and Work/School Outcomes in People With First Episode Psychosis: Testing the Effectiveness of Cognitive Self-Management Strategies

The goal of this pilot cluster randomized trial is to understand if adding a standardized cognitive self-management program, Thinking Skills for Work-Cognitive…

First Episode Psychosis (FEP)

Estimated

~$10 – $750

Actual pay is set by the research site.

Boston University Charles River CampusNCT07749105

The Prevalence of Neuropathic Pain Pathophysiology Associated With Ankle Fracture

This application addresses the Peer Reviewed Medical Research Program Investigator-Initiated Research Award FY21 W81XWH-22-CPMRP-IIRA area of Chronic Pain Mana…

Neuropathic Pain

Estimated

~$10 – $750

Actual pay is set by the research site.

Indiana UniversityNCT06420141

Testing of an Educational Tool for Patients With Melanoma and Concomitant Autoimmune Disease Who Are Candidates for Adjuvant Therapy With Immune Checkpoint Inhibitors: Acceptability and Usability With Patients and Providers

This study learn how easily patients can use an educational tool that will be created for patients with melanoma and pre-existing autoimmune diseases who recei…

Ankylosing SpondylitisAutoimmune DiseaseCrohn Disease+10 more

Estimated

~$10 – $750

Actual pay is set by the research site.

M.D. Anderson Cancer CenterNCT04751396

Interrogation of Exosome-mediated Intercellular Signaling in Patients With Pancreatic Cancer

The purpose of this study is to isolate and analyze exosomes, which are tiny carriers of important proteins and nucleic acids that serve as messenger systems i…

Pancreatic CancerBenign Pancreatic Disease

Estimated

~$10 – $750

Actual pay is set by the research site.

Memorial Sloan Kettering Cancer CenterNCT02393703

Phase 1

A Phase I, Randomized, Single-blind, Placebo-controlled Study to Assess Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD1043 Following Single and Multiple Ascending Doses Via Subcutaneous and/or Intravenous Administration in Healthy Adult Participants Living With Overweight and/or Obesity.

The purpose of the study is to assess the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of AZD1043 following single and multiple ascend…

Healthy ParticipantsObesity

Estimated

~$500 – $11,250

Actual pay is set by the research site.

AstraZenecaNCT07511205