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27,354 recruiting studies available now

Phase IB/II Study Combining All-Trans Retinoic Acid (ATRA) With Carfilzomib Based Therapy in Plasma Cell Myeloma Patients Refractory to Carfilzomib

This is a Phase IB/II trial that will investigate the safety, tolerability and efficacy of combination therapy using All-Trans Retinoic Acid (ATRA) with Carfil…

Multiple Myeloma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

The Methodist Hospital Research InstituteNCT06536413

Observational

Multi-modal Large Language Model-Empowered Talk Therapy for Older Adults With ADRD

The purpose of this study is to test the usefulness and the effect of Smart Virtual Reminiscence (SVR) therapy intervention on the Behavioral and Psychological…

Mild Cognitive ImpairmentDementiaBPSD+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Indiana UniversityNCT07499570

Phase 2

Investigating Novel Interventions for Low Back Pain in US Military Veterans: A Randomized Controlled Adaptive Phase II Trial

Chronic pain symptoms are very common among U.S. Military Veterans and have a profound negative impact on mental health symptoms and quality of life, in additi…

Chronic Low Back Pain

Estimated

~$75 – $1,800

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT05935761

Phase 1

A Phase 1/2 Study to Assess Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of TU2218, an Oral TGFβR Inhibitor, Administered Alone and in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

This study consists of Part A for monotherapy and Part B for combination therapy to evaluate safety, tolerability, pharmacokinetics, and preliminary efficacy o…

Advanced Solid Tumor

Estimated

~$150 – $4,200

Actual pay is set by the research site.

TiumBio Co., Ltd.NCT05204862

Phase 3

A Multicenter, Randomized, Controlled, Open-label, Group-Sequential, Phase 3 Study to Investigate the Efficacy, Safety, and Tolerability of Intravenous Gammagard Liquid (Immune Globulin Infusion, 10%) for Primary Infection Prophylaxis Compared With Secondary Infection Prophylaxis in Adult Subjects With Multiple Myeloma Receiving B-Cell Maturation AntigenxCD3-Directed Bispecific Antibody Therapy

Multiple myeloma is a cancer of the plasma cells in the bone marrow. The main aim of this study is to learn how well the Immune Globulin Infusion (human), 10 …

Multiple MyelomaSecondary Immunodeficiency

Estimated

~$50 – $2,250

Actual pay is set by the research site.

TakedaNCT06980480

Observational

PRecision-Controlled Ventilation to Enhance Cardiac Arrest Intervention and Survival IN CPR: A Multi-Center Randomized Controlled Trial

Cardiac arrest is a life-threatening emergency that requires immediate treatment with cardiopulmonary resuscitation (CPR). While chest compressions circulate b…

Cardiac Arrest (CA)

Estimated

~$10 – $750

Actual pay is set by the research site.

Rush University Medical CenterNCT07088120

Observational

Staged Low-Barrier and Mobile Care to Improve Retention and Viral Suppression in Hard-To-Reach Vulnerable People Living With HIV

The purpose of this study is to evaluate the implementation and effectiveness of a flexible, multidisciplinary, integrated drop-in/mobile HIV care approach for…

HIV

Estimated

~$10 – $675

Actual pay is set by the research site.

University of California, San FranciscoNCT05887557

Observational

The Use of Cytomegalovirus Cell Mediated Immunity to Optimize the Duration of Letermovir Prophylaxis in Hematopoietic Cell Transplant Recipients

The goal of this laboratory research study is to learn if interrupting a patient's letermovir dosing based on their immune system response can help HSC transpl…

Cytomegalovirus Cell Mediated ImmunityHematopoietic Cell Transplant

Estimated

~$10 – $750

Actual pay is set by the research site.

M.D. Anderson Cancer CenterNCT06639854

Phase 4

Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner Syndrome: A Non-randomized Prospective Trial (The BOOST Study)

This is a single-site open label non-randomized study comparing effects of sequential versus continuous use of progesterone supplementation amongst Turner Synd…

Turner SyndromePrimary Ovarian Insufficiency (Poi)

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Children's Mercy Hospital Kansas CityNCT06834594

Phase 1

A Phase 1/2, Multicenter, Open-Label, First-in-Human Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of DB-1324 in Participants With Advanced/Metastatic Gastrointestinal Tumors

This study, the first clinical trial, aims to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, maximum tolerated dose, and antitumor act…

Gastrointestinal Cancer

Estimated

~$150 – $4,200

Actual pay is set by the research site.

DualityBio Inc.NCT07263594

Database Linkage Study to Evaluate the Risk of Medullary Thyroid Carcinoma

This is a database linkage study utilizing real-world data (RWD) to determine whether certain medicines used to treat type 2 diabetes (T2D) and support weight …

Medullary Thyroid Carcinoma

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Novo Nordisk A/SNCT07713901

Phase 1

A Pilot Trial of Autologous Tumor Infiltrating Lymphocytes (LN-144 or LN-145) for Patients With Advanced Uveal Melanoma, Undifferentiated Pleomorphic Sarcoma, Dedifferentiated Liposarcoma, or Angiosarcoma

This is an open label study evaluating lifileucel (LN-144) in patients with metastatic uveal melanoma.

Uveal MelanomaMelanomaMetastatic Uveal Melanoma+1 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Memorial Sloan Kettering Cancer CenterNCT05607095