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27,293 recruiting studies available now

First-In-Human Trial of Miniature In-Line, Pressure-Cycled, Emergency Respirator Device in Human Organ Donors

This first-in-human pilot study will test an investigational miniature breathing device called the Hope inVent. The device is a small, single-use, in-line resp…

Brain DeathRespiration, Artificial

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institutes of Health Clinical Center (CC)NCT07768215

Phase 4

Effect of Pre-Injection Iopidine on Intraocular Pressure and Transient Vision Loss Following High-Volume Intravitreal Injections

This is a prospective, randomized, controlled, open-label, single-site investigator-initiated clinical trial. A total of 120 participants will be randomized in…

Macular DegenerationDiabetic RetinopathyRetinal Vein Occlusion+1 more

Estimated

~$25 – $1,500

Actual pay is set by the research site.

Retina Consultants of DelmarvaNCT07891910

Observational

A Novel Multimodal Approach to Promote Motor Recovery and Plasticity After Stroke

Upper extremity (UE) paresis or weakness is one of the most frequent impairments after stroke. Despite intense rehabilitation, motor and functional recovery of…

Stroke

Estimated

~$10 – $750

Actual pay is set by the research site.

University of UtahNCT07887880

Observational

Post-Operative Cosmesis and Skin Closure Methods After Cesarean Section

Given the high numbers of cesarean deliveries being performed today, there has been interest in optimizing surgical techniques. Several recent reviews have sum…

Cesarean Delivery

Estimated

~$10 – $750

Actual pay is set by the research site.

Wake Forest University Health SciencesNCT06412978

Physiology-directed Epinephrine Dosing in Pediatric Cardiac Arrest

This is a prospective, observational, multi-center cohort study of pediatric cardiac arrests. The purpose of this study is to evaluate the physiologic response…

Cardiac Arrest (CA)

Estimated

~$10 – $750

Actual pay is set by the research site.

Children's Hospital of PhiladelphiaNCT07890610

Phase 1

A Phase 1a/b, Open-label, Dose-escalation and Dose-expansion, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of MX006 in Patients With Selected Advanced Solid Tumor Types Known to Express B7-H3

This is a Phase 1a/1b, multicenter, open-label, first-in-human (FIH) study with MX006 treatment in patients with selected tumor types known to express B7-H3. T…

Advanced and/or Metastatic Solid Tumors Known to Express B7-H3

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Myricx Pharma LimitedNCT07807241

Phase 2

A Randomized Phase 2/3 Study Evaluating the Safety and Efficacy of Pivekimab Sunirine (PVEK) in Combination With Venetoclax and Azacitidine in Adult Subjects With Newly Diagnosed Acute Myeloid Leukemia (AML) Ineligible to Receive Intensive Chemotherapy

Cancer is a condition where cells in a specific part of the body grow and reproduce uncontrollably. Acute myeloid leukemia (AML) is a cancer of the blood and b…

Acute Myeloid Leukemia

Estimated

~$75 – $3,000

Actual pay is set by the research site.

AbbVieNCT07581002

Phase 1

Phase I Clinical Trial to Study the Safety and After-effects of Transcranial Magnetic Stimulation (TMS) Using A High-density Theta Burst Stimulation (hdTBS) Paradigm

Background: Transcranial magnetic stimulation (TMS) uses magnetic pulses to affect brain activity. A type of TMS called theta burst stimulation (TBS) is appro…

Healthy Volunteers

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Institute on Drug Abuse (NIDA)NCT06868914

Phase 2

Phase II Study of Osimertinib (AZD9291) in Advanced NSCLC Patients With Exon 20 Insertion Mutations in EGFR

This phase II trial studies how well osimertinib works in treating patients with non-small cell lung cancer with EGFR exon 20 insertion mutation that is stage …

Advanced Lung Non-Small Cell CarcinomaRecurrent Lung Non-Small Cell CarcinomaStage IIIB Lung Non-Small Cell Cancer AJCC v7+1 more

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT03191149

Phase 2

The MAVRiC Study: A Phase II Study of Disease Risk Mutation Guided Finite Duration Acalabrutinib Plus Venetoclax for Relapse in CLL/SLL After First-line Finite Covalent BTKi Plus BCL2i Combination, With or Without Obinutuzumab

This study will evaluate the efficacy and safety of finite-duration acalabrutinib plus venetoclax therapy in patients with relapsed CLL or SLL, who have previo…

Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)

Estimated

~$75 – $3,000

Actual pay is set by the research site.

AstraZenecaNCT07024706

Hereditary Leiomyomatosis Renal Cell Cancer (HLRCC): Identification of the Disease Gene, and Characterization of the Predisposition to Renal Cancer

This study will investigate what causes hereditary leiomyomatosis renal (kidney) cell cancer, or HLRCC, and how the disease is related to the development of ki…

Renal Tumor HistologyCutaneous LeiomyomaKidney Cancer

Estimated

~$10 – $675

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT00050752

Phase 3

A Phase III Trial of Rx Therapy Guided by Genomic Risk Assessment For High Anatomic Stage ER-pos/HER2-neg Breast Cancer With RS Less Than or Equal to 25 (RxFINE-Low)

This phase III trial compares standard of care hormone therapy plus ribociclib to chemotherapy followed by hormone therapy plus ribociclib for the treatment of…

Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIC Breast Cancer AJCC v8+2 more

Estimated

~$50 – $1,350

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT07391774