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27,295 recruiting studies available now

Efficacy of Intravenous Sub-Dissociative Ketamine Versus Intravenous Morphine in Children With Acute Pain

Pain is common in children presenting to the emergency department but is frequently undertreated, leading to both short- and long-term consequences. Morphine i…

Abdominal PainIsolated Extremity FracturePain+1 more

Estimated

~$50 – $1,500

Actual pay is set by the research site.

Columbia UniversityNCT06835504

Phase 1

A Randomized, Double-blind, Placebo-controlled Single Ascending Dose and Open-label Multi-dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intrathecally Administered ALN-APP in Adult Patients With Early-onset Alzheimer's Disease (EOAD)

The purpose of this study is to evaluate the safety, tolerability, pharmacodynamics (PD) and pharmacokinetics (PK) of a single dose and multiple doses of ALN-A…

Early-Onset Alzheimer Disease

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Alnylam PharmaceuticalsNCT05231785

Observational

The Effect of the Safe and Sound Protocol on Depression and Anxiety Symptoms

The goal of this study is to determine if a developed protocol involving modulated auditory stimulation is better than non-modulated auditory stimulation in re…

AnxietyDepression

Estimated

~$10 – $1,125

Actual pay is set by the research site.

HealthPartners InstituteNCT06701578

Phase 1

A Phase 1, Randomized, Double-Blind, Comparator-Controlled Dose-Escalation Study to Evaluate the Safety, Tolerability, and Immunogenicity of V132 in Healthy Older Participants

The goal of this study is to learn about the safety and immune response to the V132 vaccine in healthy older adults.

Healthy

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Merck Sharp & Dohme LLCNCT07712575

Pacritinib Effectiveness in Real-world Settings (PACER)

This study aims to evaluate real-world treatment patterns and effectiveness of pacritinib, including hematologic and clinical outcomes, and survival through a …

Myelofibrosis (MF)

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Swedish Orphan BiovitrumNCT07774455

Observational

Comprehensive Assessment of Reactions to Pharmacogenetics in Complex Care Patients

The goal of this clinical trial is to determine the feasibility and acceptability of Pharmacogenetic Testing, and the attitudes towards the same in caregivers …

Pediatric Medical Complexity Based on PMCA Score of 3

Estimated

~$10 – $675

Actual pay is set by the research site.

Children's Hospital Medical Center, CincinnatiNCT07060300

Phase 3

A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Maintenance of Effect of NBI-1065845 as an Adjunctive Treatment in Subjects With Major Depressive Disorder (MDD)

The primary objective of this study is to evaluate the efficacy of osavampator (previously NBI-1065845) compared with placebo as an adjunctive treatment in del…

Major Depressive Disorder

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Neurocrine BiosciencesNCT07196501

Sample Collection From Healthy Volunteers for Assay Optimization

Background: The Laboratory of Immune System Biology (LISB) works with other labs at the National Institutes of Health. They study how parts of living things c…

Healthy Volunteers

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Allergy and Infectious Diseases (NIAID)NCT03538600

Phase 3

A Phase 3, Multi-Center Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Risankizumab With Open-Label Induction, Randomized Double-Blind Maintenance, and Open-Label Long-Term Extension Periods in Pediatric Subjects (2 to < 18 Years of Age) With Moderately to Severely Active Ulcerative Colitis

Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large intestine)…

Ulcerative Colitis

Estimated

~$50 – $2,250

Actual pay is set by the research site.

AbbVieNCT07071519

Evaluation of Children With Endocrine and Metabolic-Related Conditions

Background: Endocrine glands give off hormones. Researchers want to learn more about the disorders that affect these glands in children. These disorders might…

Adrenal InsufficiencyGrowth DisorderEndocrine Diseases+2 more

Estimated

~$10 – $675

Actual pay is set by the research site.

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)NCT02769975

Phase 1

An Open-label Multi-Cohort Phase 1b/2 Study to Evaluate the Safety, Efficacy, and Optimal Dose of Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease and No Actionable Genomic Alterations

Non small cell lung carcinoma (NSCLC) is the most frequently occurring histologic subtype of lung cancer and is the leading cause of cancer-related deaths worl…

Non Small Cell Lung Carcinomac-MET

Estimated

~$150 – $4,500

Actual pay is set by the research site.

AbbVieNCT06772623

Phase 3

Phase 3, Open-label, Single-dose, Multicenter Study Investigating Efficacy, Safety, and Tolerability of CSL222 (Etranacogene Dezaparvovec) Administered to Adolescent Male Subjects (≥ 12 to < 18 Years of Age) With Severe or Moderately Severe Hemophilia B

This is a phase 3, prospective, open-label, single-arm, single-dose, multicenter study investigating the efficacy, safety, and tolerability of CSL222 (AAV5-hFI…

Hemophilia B

Estimated

~$50 – $2,250

Actual pay is set by the research site.

CSL BehringNCT07080905