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27,295 recruiting studies available now

Microneurographic Assessment of Peripheral Nerves in Healthy Volunteers and Individuals With Sensory Dysfunction Caused by Inherited Mutations in the PIEZO2 Gene

Background: PIEZO2 Deficiency Syndrome (PDS) is a genetic disorder that affects a person s ability to feel touches and pain. Researchers want to know more abo…

PIEZO2-Deficiency Syndrome

Estimated

~$10 – $1,125

Actual pay is set by the research site.

National Center for Complementary and Integrative Health (NCCIH)NCT06052631

Phase 1

Phase I Study Evaluating Hepatic Artery Infusion of Carfilzomib in Participants With Liver Metastatic Disease Previously Treated With Hepatic Artery Infusion Pump Therapy

Background: Cancers that begin in the colon, adrenal glands, or bile ducts may spread to the liver. These liver tumors are often treated using a hepatic arter…

Colorectal NeoplasmsNeoplasmsIntrahepatic Cholangiocarcinoma+2 more

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT07715903

Phase 3

A Phase III, Multicentre, Randomised, Open-label Study to Compare the Efficacy and Safety of AZD0486 Plus Rituximab Versus Chemotherapy Plus Rituximab in Previously Untreated Participants With Follicular Lymphoma (SOUNDTRACK-F1)

This is a global, randomised, Phase III, multicentre, open-label study evaluating the efficacy, safety and the degree of added benefit of the Surovatamig (AZD0…

Untreated Follicular Lymphoma

Estimated

~$50 – $2,250

Actual pay is set by the research site.

AstraZenecaNCT06549595

Phase 2

A Phase II Study to Examine the Impact of CD22 CAR T-cells to Extend the Duration of Remission Following Commercial CD19 CAR T-cells in Children, Adolescents, and Adults With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia

Background: Acute lymphoblastic leukemia (ALL) is a type of blood cancer. Chimeric antigen receptor (CAR) therapy involves taking immune cells (T cells) from …

Acute Lymphoblastic LeukemiaB-All

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT07328503

Phase 3

A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures

This is a clinical research study for an investigational drug called RAP-219 in adult participants with focal seizures. This study is being conducted to determ…

Focal SeizureEpilepsyFocal Epilepsy

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Rapport Therapeutics Inc.NCT07563881

Phase 1

Topical Insulin for Glaucoma and Optic Neuropathies

The purpose of this Phase 1 trial is to determine the safety over 1-2 months of topic sterile human recombinant insulin on subjects with optic neuropathies (gl…

Glaucoma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Stanford UniversityNCT05206877

Long-Term CLinical Evaluation of Aspiration ThRombectomy Using the Symphony or ProdIgy Thrombectomy System - CLEAR-IT

The study is designed to evaluate the short-term and long-term clinical performance and safety of the Symphony and Prodigy thrombectomy systems used in endovas…

Arterial ThromboembolismVenous ThromboembolismPulmonary Embolism

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Imperative Care, Inc.NCT07350499

Phase 3

A Phase 3, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Rezpegaldesleukin (NKTR-358) Monotherapy in the Treatment of Patients ≥ 12 Years of Age With Moderate-to-Severe Atopic Dermatitis

This is an interventional, randomized, parallel group, treatment, Phase 3, double blind study to assess the effect of Rezpegaldesleukin in participants 12 year…

Moderate-to-Severe Atopic Dermatitis

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Nektar TherapeuticsNCT07690371

Observational

A Prospective Study on the Effect of Auricular Percutaneous Electrical Nerve Field Stimulation (PENFS) in Patients With Post Concussion Syndrome (PCS)

The purpose of this study is to test the effect of Auricular Percutaneous Electrical Nerve Field Stimulation (a Neurostim device) on children with pain and Pos…

Post-Concussion SyndromeCOVID Long-HaulCOVID-19

Estimated

~$10 – $750

Actual pay is set by the research site.

Children's Hospital of Orange CountyNCT04978571

Phase 2

APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

This phase II trial investigates how well the addition of olaparib following completion of surgery and chemotherapy works in treating patients with pancreatic …

Pancreatic Acinar Cell CarcinomaPancreatic Adenosquamous CarcinomaPancreatic Squamous Cell Carcinoma+4 more

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT04858334

Observational

Remote vs. In-Person Study Evaluation (RISE) Above Depression

The study will employ a randomized, parallel-group design with two-stage randomization. After an initial brief screen for basic eligibility, participants will …

Remote vs. In-PersonRemote VisitsIn-person Visits

Estimated

~$10 – $750

Actual pay is set by the research site.

State University of New York at BuffaloNCT07854301

Observational

The Effects of AFO Heel Height and Stiffness on Gait

The proposed study evaluates the effect of ankle foot orthosis (AFO) heel height and stiffness on the forces and motion of the lower limb during over-ground wa…

Musculoskeletal InjuryMusculoskeletal DiseasesPeripheral Nervous System Diseases

Estimated

~$10 – $750

Actual pay is set by the research site.

University of IowaNCT04800484