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27,297 recruiting studies available now

Electrostimulation and Vibration as a Non-Pharmacological Adjunct to Local Anesthesia in Mohs Micrographic and Dermatologic Surgery

The E-MOHS Trial is a randomized controlled trial evaluating whether active vibration plus transcutaneous electrical nerve stimulation reduces pain during loca…

PainProcedural PainLocal Anesthesia+2 more

Estimated

~$10 – $6,250

University of MinnesotaNCT07852455

A Natural History Study of Bone and Mineral Disorders

This study has four objectives: 1) to provide investigators the opportunity to study bone specimens from patients with various skeletal diseases; 2) to treat p…

Tumor Induced OsteomalciaOsteomalaciaFamilial Tumoral Calcinosis

Estimated

~$10 – $675

National Institute of Dental and Craniofacial Research (NIDCR)NCT00024804

Phase 2

A Phase II Basket Study of the Oral TRK Inhibitor Larotrectinib (BAY2757556) in Subjects With NTRK Amplification Positive and Pan-TRK Positive Tumors

This phase II trial studies the effect of larotrectinib in treating patients with NTRK gene amplification positive solid tumors that have spread to nearby tiss…

Locally Advanced Malignant Solid NeoplasmMetastatic Malignant Solid Neoplasm

Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT04879121

CGM- and Behavior-based Large Health Model for Just-in-time Diabetes Management

The primary objective of this research, funded by Samsung Strategic Alliance for Research and Technology, is to develop multi-modal foundation models that inte…

Type 2 Diabetes

Estimated

~$10 – $750

Johns Hopkins UniversityNCT07633171

Phase 2

Phase II Trial of Combination Anti-PD-1 and Aldesleukin for Metastatic Melanoma and Renal Cell Carcinoma

Background: Aldesleukin is used to treat metastatic or advanced melanoma and renal cell carcinoma. Pembrolizumab is used to treat many cancers including melan…

Metastatic MelanomaAdvanced Locoregional MelanomaMetastatic Renal Cell Carcinoma+1 more

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT05155033

Observational

Minimally Invasive Post-Traumatic Craniofacial Soft Tissue Regeneration: Validation of Safety and Efficacy of Staged Approach Using Autologous Fresh Fat Grafting Followed by Autologous Cryopreserved Fat Grafting

The goal of this clinical trial is to validate the safety and effectiveness of a two-stage approach for minimally invasive craniofacial soft tissue reconstruct…

Facial Defect

Estimated

~$10 – $6,250

University of PittsburghNCT06747715

Phase 2

Clofutriben And Placebo Phase 2 Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

CAPTAIN-T2D will take place in two parts. Part 1 (Screening) will evaluate patients with type 2 diabetes and elevated cortisol risk factors for trial eligibili…

Type 2 DiabetesCortisol Excess

Estimated

~$10 – $8,750

Sparrow PharmaceuticalsNCT07296484

Phase 3

A Master Protocol to Investigate the Efficacy and Safety of Orforglipron Tablet Once Daily Compared With Placebo in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight

The GZPS master protocol will support two independent studies, J2A-MC-GZS1 and J2A-MC-GZS2. Each study will see how well and safely orforglipron works in adult…

Urinary Incontinence,Stress

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07202884

Phase 3

A Phase 3, Multicenter, Double-Blind, Placebo-controlled Study Assessing the Efficacy and Safety of Olomorasib in Combination With Standard of Care Immunotherapy in Participants With Resected or Unresectable KRAS G12C-Mutant, Non-Small Cell Lung Cancer - SUNRAY-02

The main purpose of this study is to assess if olomorasib in combination with pembrolizumab is more effective than the pembrolizumab and placebo combination in…

Carcinoma, Non-Small-Cell Lung

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT06890598

Phase 3

A Master Protocol for a Randomized, Controlled, Clinical Platform Trial to Investigate the Efficacy and Safety of Interventions for Chronic Weight Management in Pediatric Participants With Obesity or Overweight

The purpose of this pediatric, chronic weight management, Phase 3 Master Protocol (PWMP) is to create a framework to evaluate the safety and efficacy of pharma…

ObesityOverweight

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT06672549

Phase 1

A Phase I/II, Open-label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of Vactosertib as a Single Agent in Adolescents and Adults With Recurrent, Refractory or Progressive Osteosarcoma

MP-VAC-209 is a Phase I/II, open label, single arm, multi-center study to assess safety, tolerability, and antitumor activity of vactosertib as a single agent …

Osteosarcoma

Estimated

~$10 – $8,750

MedPacto, Inc.NCT05588648

Phase 2

A Randomized Phase II Trial for High-Risk Multiple Myeloma That is Refractory or in First Relapse With Daratumumab, Teclistamab (DT) Versus Daratumumab, Pomalidomide, Dexamethasone (DPd) or Daratumumab, Carfilzomib, Dexamethasone (DKd)

This phase II trial compares the effect of the combination of daratumumab-hyaluronidase (daratumumab) and teclistamab to the usual treatment of daratumumab, po…

Recurrent Multiple MyelomaRefractory Multiple Myeloma

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT06948084