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27,295 recruiting studies available now

The IMPACT Study: A Randomized Controlled Trial of Individualized Management Post Ventral Hernia Repair (VHR) Utilizing Abdominal Core Therapy for Enhanced Recovery and Health Outcomes

Ventral hernia repair is among the most common operations performed in the United States each year, yet the great majority of patients receive no structured re…

Ventral HerniaVentral Incisional HerniaPost Operative Pain

Estimated

~$10 – $750

Actual pay is set by the research site.

Thomas Jefferson UniversityNCT07145099

Observational

Comparing the Effectiveness of a Biomarker-plus-clinical Guidelines Algorithm Versus Clinical Guidelines Only for Safely Decreasing Brain Computed Tomography Utilization During Brain Injury Evaluations: The PIONEER Comparative Effectiveness Study

This is a pragmatic, open-label, multicenter, stepped-wedge, Type II hybrid effectiveness-implementation study. It is designed to evaluate both the comparative…

Head Injury TraumaTraumatic Brain Injury, Mild

Estimated

~$10 – $750

Actual pay is set by the research site.

University of MichiganNCT07829107

Phase 1

Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)

Background: In people with multiple sclerosis (MS), brain and cerebrospinal fluid (CSF) biomarkers indicate inflammation or disease. Researchers want to see i…

Multiple Sclerosis

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Institute of Allergy and Infectious Diseases (NIAID)NCT03109288

Phase 2

Nemtabrutinib for Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Leukemia (SLL) Refractory to Covalent Bruton Tyrosine Kinase Inhibitor or Pirtobrutinib and Previously Treated With a BCL2 Inhibitor

Background: Chronic lymphocytic leukemia (CLL)/small lymphocytic leukemia (SLL) are diseases in which the body makes too many white blood cells that do not wo…

Chronic Lymphocytic LeukemiaSmall Lymphocytic Leukemia

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Heart, Lung, and Blood Institute (NHLBI)NCT07796373

Phase 3

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Veverimer in Adults With CKD and Metabolic Acidosis

The purpose of this study is is to evaluate the efficacy and safety of veverimer in treating adults with moderate-to-severe chronic kidney disease (CKD) and me…

CKDMetabolic Acidosis

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Renibus Therapeutics, Inc.NCT07355062

Phase 3

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Revumenib in Combination With Intensive Chemotherapy in Participants With Newly Diagnosed AML With an NPM1 Mutation

The purpose of this study is to assess if adding revumenib to standard chemotherapy improves outcomes in participants with AML with certain genetic mutations c…

Acute Myeloid Leukemias

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Syndax PharmaceuticalsNCT07211958

Phase 3

A 2-Part, Phase 3, Multicenter, Randomized, Open-Label, Active-Controlled Study to Assess Efficacy and Safety of REGN7508, a Monoclonal Antibody Against Factor XI, for the Treatment and Secondary Prevention of Venous Thromboembolism in Participants With Solid and Hematologic Cancers (ROXI-CAT-II)

This study is researching an experimental drug called REGN7508 (called "study drug") and will consist of 2 parts: Part 1 and Part 2. The study is focused on pa…

Venous Thromboembolism (VTE)

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Regeneron PharmaceuticalsNCT07493304

Observational

Multicenter National Parallel Cluster Randomized Controlled Superiority Trial Comparing an Artificial Intelligence-Based Screening Strategy to Usual Care for Improving Eye-Care Follow-Up Among Patients With Diabetes (AI-BRIDGE Trial)

This pragmatic clinical trial is being conducted to test the effectiveness of AI-BRIDGE (Artificial Intelligence-Based point of caRe, Incorporating Diagnosis, …

Diabetic RetinopathyDiabetes Mellitus

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Wisconsin, MadisonNCT06763952

Phase 2

A Phase 2/3 Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Investigate the Safety and Efficacy of Oral Brepocitinib in Adults With Cutaneous Sarcoidosis

This study will evaluate the clinical safety and efficacy of oral brepocitinib in participants with cutaneous sarcoidosis.

Cutaneous Sarcoidosis

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Priovant Therapeutics, Inc.NCT06978725

Phase 1

A Feasibility/Pilot First-in-human Study of Exercise-mobilized NK-enriched Donor Lymphocyte Infusions (DLI-X) to Prevent Leukemia Relapse After Allogeneic Hematopoietic Cell Transplantation

The primary objective of this proposal is to conduct the first-in-human randomized clinical trial evaluating prophylactic DLI-X (pro-DLI-X) for relapse prevent…

Acute Lymphoid LeukemiaAcute Myeloid LeukemiaAcute Undifferentiated Leukemia (AUL)+3 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of ArizonaNCT07254793

Phase 1

Pilot Study to Assess the Contribution of UGT2B17 and Associated Genetic Polymorphisms on the Pharmacokinetics of Diclofenac Alone and Upon Co-administration With Curcumin

The purpose of this pilot study is to gather preliminary data on the (1) contribution of the understudied drug metabolizing enzyme, UDP-glucuronosyltransferase…

Interaction

Estimated

~$500 – $7,500

Actual pay is set by the research site.

Washington State UniversityNCT06053411

Phase 1

Causal Mechanisms of Odor-Guided Behavior in Humans

Background: Little is known about how different regions of the brain responsible for the human sense of smell guide behaviors. In this study, researchers use …

Normal Physiology

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Institute on Drug Abuse (NIDA)NCT07099092