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A Pilot Study To Assess The Effect Of Antepartum Perineal Massage Using A Pelvic Wand On Labor Agency And Pelvic Health

There is limited research on the optimal strategy to reduce obstetric laceration, postpartum urinary retention, and postpartum pelvic pain. In systematic revie…

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Beth Israel Deaconess Medical CenterNCT06986824

Observational

Caregiver-assisted Pain Coping Skills Training for Dementia Pilot Study

The purpose of the study is to develop a caregiver-assisted pain coping skills training program for older adults who have pain and mild to moderate dementia an…

PainDementia, MildDementia, Moderate

Estimated

~$10 – $750

Actual pay is set by the research site.

Duke UniversityNCT06854718

Determining the Success of a Urine Metabolite Point-of-care Colorectal Cancer Early Diagnosis Test in Africa

The purpose of this study is to find out whether a urine test can detect colorectal cancer (CRC) and precancerous polyps in participants living in Ghana, Tanza…

Colorectal CancerPrecancerous PolypRectal Bleeding+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Memorial Sloan Kettering Cancer CenterNCT07649057

Phase 1

A Phase 1b/2 Study to Demonstrate the Safety and Efficacy of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an Ileal Pouch-Anal Anastomosis (PROF). The "PROF" Study.

The aim of this study is to assess the safety and preliminary efficacy of treatment with EXE-346, a live biotherapeutic, which may reduce bowel movement freque…

Ileal Pouch

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Exegi Pharma, LLCNCT05938465

Phase 1

A Pilot Safety and Feasibility Study of Lymphodepleting Total Body Irradiation (TBI) Plus Cyclophosphamide Prior to Ciltacabtagene Autoleucel (Carvykti; Cilta-cel) for Multiple Myeloma (MM) Patients With Impaired Renal Function

Treatment for relapsed/refractory multiple myeloma continues to evolve with the approval of highly effective anti-BCMA CAR T therapies in recent years. However…

Multiple Myeloma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Washington University School of MedicineNCT06623630

Observational

Osteopathic Manipulative Therapy(OMT) Effects on Post-Acute Sequalae of COVID-19(PASC)

This study is investigating the effects of using an Osteopathic Manipulative Therapy (OMT) treatment protocol that was shown to statistically improve smell in …

Long-COVIDPASCLong COVID Syndrome

Estimated

~$10 – $750

Actual pay is set by the research site.

University of LouisvilleNCT06883513

Observational

Cardiometabolic Risk Effects of Short-term Cessation of Effective Neurostimulation Therapy in OSA

Hypoglossal nerve stimulation (HGNS) is an implantable therapy that treats obstructive sleep apnea. The study will evaluate the effect of this treatment on ca…

Obstructive Sleep ApneaObstructive Sleep Apnea of Adult

Estimated

~$10 – $750

Actual pay is set by the research site.

Columbia UniversityNCT06720545

Phase 4

Pain with Differing Intraperitoneal Washes At the End of Laparoscopic Gynecologic Surgery

We hypothesize that instilling intraperitoneal Marcaine (without epinephrine) at the end of a non-total laparoscopic gynecologic surgery (adnexa only, which in…

Laparoscopic Adnexal Surgery

Estimated

~$25 – $1,000

Actual pay is set by the research site.

University of TennesseeNCT06842771

Phase 2

A Randomized Phase II Trial Comparing Daratumumab-Bortezomib-Dexamethasone Versus Cyclophosphamide-Bortezomib-Dexamethasone in Newly Diagnosed Multiple Myeloma With Light Chain Cast Nephropathy (LCCN)

This study is being done to answer the following question: Can the addition of daratumumab-hyaluronidase to the usual treatment of bortezomib and dexamethason…

Myeloma Multiple

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Eastern Cooperative Oncology GroupNCT07085728

Observational

Adaptation and Examination of a Trauma-informed Intervention for Pregnant Veterans (CDA 22-135)

The current proposal aims to refine and examine an intervention called Calm Moms. Calm Moms is a web-based treatment program designed to reduce anxiety, stress…

Trauma-related Mental Health Symptoms

Estimated

~$10 – $675

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT06906185

Observational

MyHand-SCI: A Wearable Robotic Hand Orthosis for C6-C7 Spinal Cord Injury

The purpose of this study is to develop and test the hardware and software components of the MyHand-SCI device to assist with hand function for individuals wit…

Spinal Cord InjuriesTetraplegia

Estimated

~$10 – $750

Actual pay is set by the research site.

Columbia UniversityNCT05553457

Phase 2

Phase 2 Study of Systemic IL-6 Receptor Antagonist ACTEMRA® (Tocilizumab) for the Treatment of Progressive/Recurrent Pediatric Adamantinomatous Craniopharyngioma

ACTEMRA (tocilizumab) is an IL-6 receptor antagonist used for the treatment of adult Rheumatoid Arthritis as well as Polyarticular (PJIA) and Systemic (SJIA) J…

Adamantinomatous CraniopharyngiomaRecurrent Adamantinomatous Craniopharyngioma

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Nationwide Children's HospitalNCT05233397