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27,384 recruiting studies available now

Phase II Clinical Trial Combining the Hedgehog Inhibitor Vismodegib With the PD-L1 Inhibitor Atezolizumab in Patients With Platinum Resistant Ovarian, Fallopian Tube, and Primary Peritoneal Cancer

This trial will treat patients with platinum resistant ovarian, fallopian tube or primary peritoneal cancer as defined by a progression free interval within si…

Platinum-Resistant Fallopian Tube CarcinomaPlatinum-Resistant Primary Peritoneal CarcinomaPARP Inhibitor+1 more

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Ronald BuckanovichNCT05538091

Phase 1

RADIANT Study: Pre-op Radiation With Abemaciclib Andletrozole in Early Stage Breast Cancer

This phase 1b study investigates the safety and feasibility of combining pre-operative radiation therapy with Cyclin-Dependent Kinase 4 (CDK4/6) inhibitors in …

Breast Cancer

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Mridula George, MDNCT06139107

Phase 2

IZABRIGHT-Breast01: A Randomized, Open-label, Phase 2/3 Study of Izalontamab Brengitecan (BMS-986507) Versus Treatment of Physician's Choice in Patients With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer (TNBC) or ER-low, HER2-negative BC Who Are Ineligible for Anti-PD1/PD-L1 Treatment

The purpose of this study is to assess the efficacy and safety of iza-bren, a bi-specific antibody-drug conjugate against EGFR and HER3 with a topoisomerase in…

Breast Neoplasms

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Bristol-Myers SquibbNCT06926868

Phase 4

A Randomized Control Trial for Opioid Use After Laparoscopic Salpingectomy

The purpose of this study is to evaluate patient-reported post-operative pain scores following minimally invasive tubal sterilization procedures to determine i…

Opioid UsePost-operative PainSterility, Female

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Johns Hopkins UniversityNCT06434233

Phase 1

Evaluation of the Distribution of CM500 in Healthy Volunteers and Patients With Cancer

The objective of this study is to assess two novel positron emission tomography (PET) radiotracers, \[64Cu\]CM500 and \[68Ga\]CM500, for Positron Emission Tomo…

Bladder CancerGliomaGlioblastoma (GBM)+13 more

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Lumina Pharmaceuticals IncNCT07781852

Observational

Genetic Biomarkers of Intermittent Hypoxia-Induced Respiratory Motor Plasticity in Chronic SCI

Acute intermittent hypoxia (AIH) involves brief (1 min), repeated episodes (\~15) of breathing low oxygen air to stimulate spinal neuroplasticity. Animal and h…

Spinal Cord Injuries

Estimated

~$10 – $750

Actual pay is set by the research site.

University of FloridaNCT06011876

Observational

Short-messaging Services (SMS) Text for Uncontrolled Diabetes Among Persons Experiencing Homelessness

This mixed method study includes a Randomized Controlled Trial (RCT) and qualitative methods to assess the impact of a SMS text strategy in diabetes control am…

Diabetes Mellitus

Estimated

~$10 – $750

Actual pay is set by the research site.

George Washington UniversityNCT05616026

Observational

Melanin and Dermal Uptake of Thirdhand Cigarette Smoke

This is a pilot study of the effects of dermal melanin on dermal uptake and retention of nicotine. The initial hypothesis is that higher levels of dermal melan…

Healthy

Estimated

~$10 – $675

Actual pay is set by the research site.

University of California, San FranciscoNCT06020248

The Arch Watch Study: An Integrated Evaluation of Hemodynamics During Monitoring of Ductus Arteriosus Closure in Infants With Suspected Coarctation of the Aorta

Unrecognized coarctation of the aorta (CoA) is a life-threatening component of congenital heart disease (CHD) in which narrowing of the aorta causes obstructed…

Coarctation of the AortaAortic Arch Obstruction

Estimated

~$10 – $750

Actual pay is set by the research site.

Boston Children's HospitalNCT05880576

Phase 2

A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of V940 in Combination With Pembrolizumab and Chemotherapy as First-Line Treatment for Participants With Metastatic Squamous NSCLC (INTerpath-013)

Researchers want to know if intismeran autogene (the study treatment) given with pembrolizumab and chemotherapy can treat metastatic treatment-naive squamous n…

Squamous Non-small Cell Lung Cancer

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Merck Sharp & Dohme LLCNCT07221474

Phase 1

A Phase 1, Open-Label, Single-Dose, Parallel-Group Study to Evaluate the Pharmacokinetics of Casdatifan (AB521) in Participants With Moderate Hepatic Impairment Compared to Healthy Matched Participants

The purpose of the study is to compare the single dose PK of casdatifan between participants with moderate hepatic impairment (HI) and healthy matched control …

Healthy ParticipantsHepatic Impairment

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Arcus Biosciences, Inc.NCT07751250

Observational

Technology Assisted Treatment for Trichotillomania

The investigators are testing two digital health interventions for trichotillomania (TTM), via a randomized trial design.

Trichotillomania

Estimated

~$10 – $1,050

Actual pay is set by the research site.

HabitAware Inc.NCT05118633