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27,384 recruiting studies available now

A First-in-human Phase I, Open-label, Multicentre, Dose Escalation Trial of BI 3819026 in Combination With Ezabenlimab in Patients With Unresectable Advanced or Metastatic Solid Cancers to Determine the Maximum Tolerated Dose (MTD) and Recommended Dose for Expansion (RDE)

This study is open to adults with advanced cancer. The purpose of this study is to find the highest dose of BI 3819026 that people with advanced cancer can tol…

Advanced Solid CancerMetastatic Solid Cancer

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Boehringer IngelheimNCT07607678

Phase 1

Phase 1/2 First-in-Human Study to Evaluate the Safety, Tolerability, and Efficacy of MZ-1866, an AAV-9 Gene Therapy Delivered by Intracerebroventricular Injection to Participants With Pitt Hopkins Syndrome

The goal of this clinical trial is to learn if MZ-1866 is a safe and tolerable treatment for children and adults with Pitt Hopkins Syndrome. To evaluate the s…

Pitt Hopkins Syndrome

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Mahzi TherapeuticsNCT07135050

Phase 3

Randomized Controlled Trial of Ultra-Low Contrast Coronary Angiography During Acute Kidney Injury (AKI)

The aim of this study is to evaluate the safety of ultra-low contrast coronary angiography in patients with pre-existing acute kidney injury.

Acute Kidney Injury

Estimated

~$50 – $1,500

Actual pay is set by the research site.

Tulane UniversityNCT05906758

Phase 2

Phase 2, Randomized, Double-Blind, Placebo-Controlled, Safety and Efficacy Study of Anti-CD14 Treatment With a Recombinant Chimeric Monoclonal Antibody (IC14) in Hospitalized Patients With Acute Respiratory Distress Syndrome

Hospitalized patients with ARDS will be randomized to intravenous treatment with a monoclonal antibody against CD14, called IC14, or placebo. They will be foll…

Acute Respiratory Distress SyndromeAdult Respiratory Distress SyndromeAcute Lung Injury+1 more

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Implicit BioscienceNCT06513949

Observational

Influence of Acute Mental Fatigue on Muscle Strength and Limb Symmetry in Healthy Adults

This study will investigate the acute effects of mental fatigue on lower-extremity muscle strength and limb symmetry in healthy young adults. Participants will…

Mental FatigueMuscle Strength Dynamometer

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Florida Institute for Human and Machine CognitionNCT07846618

Phase 1

Pilot Study of Anti-CD19 Chimeric Antigen Receptor T Cells (CAR-T Cells) for the Treatment of Relapsed/Refractory CD19+ Malignancies

This is an open label, non-randomized, phase 1 study of anti-CD19 CAR-T cells against relapsed CD19 positive NHL, CLL and ALL based in a lymphodepletion regime…

Acute Lymphoblastic LeukemiaDiffuse Large B Cell Lymphoma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of UtahNCT06227026

Observational

The Carevix Device: Assessing Pain and Effectiveness of a Suction-based Cervical Stabilizer for IUD Insertions in the Clinic Setting: a Randomized, Controlled Trial (CARE)

The goal of this clinical trial is to evaluate patient-reported pain, bleeding, and device efficiency along with provider satisfaction and ease of use between …

IUDAbnormal Uterine BleedingPain, Cervical

Estimated

~$10 – $750

Actual pay is set by the research site.

Indiana UniversityNCT07290517

Phase 4

Effect of Albumin Versus Routine Care on Hemodynamic Response and Stability in Patients With Preeclampsia Guided by a Non-invasive Hemodynamic Monitoring System During Cesarean Delivery With Spinal Anesthesia - A Randomized Controlled Study

The purpose of this study is to compare the effect of albumin versus routine care on hemodynamic response and stability in pre-eclamptic patients during cesare…

Pre-Eclampsia

Estimated

~$25 – $1,000

Actual pay is set by the research site.

The University of Texas Health Science Center, HoustonNCT06107335

Observational

A Multicenter, Prospective, Randomized Controlled Clinical Trial Assessing the Efficacy of a Novel Cellular, Acellular, Matrix-like Product (CAMP) Plus Standard of Care Versus Standard of Care Alone in the Management of Post-Mohs Micrographic Surgery Defects.

A multicenter, prospective, randomized controlled clinical trial assessing the efficacy of a novel cellular, acellular, matrix-like product (CAMP) plus standar…

Mohs Micrographic SurgeryCutaneous MalignancyMohs Surgical Defect

Estimated

~$10 – $1,125

Actual pay is set by the research site.

BioLab HoldingsNCT07695389

Phase 2

Duloxetine Plus Exercise to Improve Physical Function in Veterans With Knee Osteoarthritis, Pain, and Psychological Comorbidity

Knee osteoarthritis (KOA) is one of the most common causes of chronic pain, mobility problems, and disability among United States Veterans. Many Veterans with …

Knee OsteoarthritisPainDepression

Estimated

~$75 – $1,800

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT07649291

Observational

Pilot Trial of Network-Based Implementation Strategies to Increase Coalition Adoption and Early Implementation of Evidence-Informed Strategies for Child Health

Community coalitions bring together residents and organizations to improve child health, but they may need support to identify and put research-supported strat…

Childhood ObesityEvidence-Based PracticeFood Systems+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of PittsburghNCT07804550

Phase 2

Palliative Dose Escalated Radiation for Painful Non-Spine Bone Metastases and Painful Non-Bone Metastases

The investigators hypothesize that with dose escalation to 40-50 Gy in ten fractions, the complete pain response rate at one month can be increased to 40-50% i…

Neoplasm MetastasesMetastases, Neoplasm

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Rutgers, The State University of New JerseyNCT05419518