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A Randomized, Multi-center, Double-blind, Sham-controlled, Phase III Clinical Study to Evaluate the Efficacy and Safety of Intrathecally Administered Rugonersen in Pediatric and Adult Participants With Angelman Syndrome

Purpose of the study is to evaluate the efficacy and safety of intrathecally administered rugonersen in pediatric and adult participants with Angelman syndrome.

Angelman Syndrome

Estimated

~$50 – $2,100

Actual pay is set by the research site.

OHB Pediatrics Ltd.NCT07605429

Phase 1

HERTHENA-Breast-01: A Phase 1b/2, Multicenter, Open-label, Dose-Finding Study to Evaluate the Safety and Antitumor Activity of Patritumab Deruxtecan in Participants With HER2 Positive Unresectable Locally Advanced Breast Cancer or Metastatic Breast Cancer

Researchers want to learn if patritumab deruxtecan (MK-1022) can treat certain breast cancers. The breast cancers being studied are HER2 positive unresectable …

Breast NeoplasmsBreast Cancer

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Merck Sharp & Dohme LLCNCT06686394

CSP #595 - Pulmonary Health and Deployment to Southwest Asia and Afghanistan

The purpose of the study is to better understand the health, including lung health, of Veterans who deployed in support of Operation Enduring Freedom (OEF), Op…

Pulmonary Function

Estimated

~$10 – $675

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT02825654

Impact of Collaborative Care for Pregnant Women With Opioid Use Disorder in Low-Resource Obstetric Settings

The investigators seek to adapt a collaborative care model (CCM) for community-based, low-resource obstetric settings and to test the effects of this adapted C…

PregnancyPostpartum PeriodOpioid Use Disorder

Estimated

~$10 – $750

Actual pay is set by the research site.

University of PittsburghNCT06956352

Phase 3

Randomized Phase III Study of Mosunetuzumab vs. Rituximab for Low Tumor Burden Follicular Lymphoma

This phase III trial compares the effectiveness of rituximab to mosunetuzumab in treating patients with follicular lymphoma with a low tumor burden. Rituximab …

Classic Follicular LymphomaFollicular Lymphoma With Unusual Cytological Features

Estimated

~$50 – $1,350

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT06337318

Sensor-based Congestion Alert for Events in Peritoneal Dialysis (SCALE-PD)

To explore the use of the Bodyport Cardiac Scale in predicting worsening of events due to fluid overload in patients with kidney disease on peritoneal dialysis.

Kidney DiseasePeritoneal Dialysis (PD)End Stage Kidney Disease (ESRD)

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Bodyport Inc.NCT07059962

Observational

The Effects of AFO Heel Height and Stiffness on Gait

The proposed study evaluates the effect of ankle foot orthosis (AFO) heel height and stiffness on the forces and motion of the lower limb during over-ground wa…

Musculoskeletal InjuryMusculoskeletal DiseasesPeripheral Nervous System Diseases

Estimated

~$10 – $750

Actual pay is set by the research site.

University of IowaNCT04800484

Observational

Empower EI: Comparing Early Intervention Approaches to Improve Communication in Toddlers With Developmental Delays

This study is testing three ways to deliver Early Intervention (EI) services for toddlers with developmental disabilities (DD). Children enrolled in EI speech…

Developmental Delays

Estimated

~$10 – $750

Actual pay is set by the research site.

Northwestern UniversityNCT07227974

Phase 2

Phase 2/3, Multicenter, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Etentamig and Daratumumab (Etentamig+D) Compared to Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Subjects With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant

Multiple myeloma (MM) is a cancer of the blood's plasma cells. The cancer is typically found in the bones and bone marrow (the spongy tissue inside of the bone…

Multiple Myeloma

Estimated

~$75 – $3,000

Actual pay is set by the research site.

AbbVieNCT07095452

Observational

Safety and Efficacy of Endovascular Treatment of Intracranial Aneurysms With Surpass Elite With GUARDian Flow Diverter

The objective of the Safety and Efficacy of Endovascular Treatment of Intracranial Aneurysms with Surpass Elite with GUARDian Flow Diverter (GUARD) trial is to…

AneurysmAneurysm, Intracranial

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Stryker NeurovascularNCT06872684

Phase 2

Optimizing Antibody-Drug Conjugate Therapy Through Molecular Analysis for Therapy Choice (ADC MATCH)

This phase II ADC MATCH screening and multi-sub-study treatment trial is evaluating whether biomarker-directed treatment with one of three antibody-drug conjug…

Advanced Malignant Solid NeoplasmMetastatic Malignant Solid Neoplasm

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT06311214

Phase 3

A Phase III Trial to Evaluate the Efficacy of the Addition of Inotuzumab Ozogamicin (a Conjugated Anti-CD22 Monoclonal Antibody) to Frontline Therapy in Young Adults (Ages 18-39 Years) With Newly Diagnosed Precursor B-Cell ALL

This phase III trial studies the side effects of inotuzumab ozogamicin and how well it works when given with frontline chemotherapy in treating patients with n…

B Acute Lymphoblastic Leukemia

Estimated

~$50 – $1,500

Actual pay is set by the research site.

Alliance for Clinical Trials in OncologyNCT03150693