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An Open-label, Multicenter, Dose Escalation and Expansion Phase 1/2 Study to Evaluate the Safety, Tolerability and Pharmacokinetics, and Anti-tumor Activity of GI-102, a CD80-IgG4 Fc-IL-2v Bispecific Fusion Protein, As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced or Metastatic Solid Tumors (KEYNOTE-G08)

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and therapeutic activity of GI-102 as a single agent and in combination wi…

Advanced Solid TumorMetastatic Solid TumorSoft Tissue Sarcoma (STS)+6 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

GI Innovation, Inc.NCT05824975

Observational

Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction (PROTECT-ICD)

The PROTECT-ICD trial is a physician-led, multi-centre randomised controlled trial targeting prevention of sudden cardiac death in patients who have poor cardi…

Sudden Cardiac Death

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Western Sydney Local Health DistrictNCT03588286

Investigating the Longitudinal Relationships Between Visual Pathway Injury, Radiological and Blood Biomarkers in Multiple Sclerosis and Related Disorders

This study is being conducted to investigate risk factors for disability progression in Multiple Sclerosis and related disorders (MSRD). The primary goal is to…

Multiple SclerosisMultiple Sclerosis, Relapsing-RemittingMultiple Sclerosis, Primary Progressive+8 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Cedars-Sinai Medical CenterNCT05204459

Pharmacogenetics and Pharmacokinetics of Oxycodone to Personalize Postoperative Pain Management Following Lumbar Spinal Fusion and Decompression Surgery in Adults

The proposed research is an important extension of an ongoing perioperative personalized analgesia and intravenous opioid pharmacogenetic research. This resear…

Lumbar Spine StenosisLumbar Spine Degeneration

Estimated

~$10 – $1,050

Actual pay is set by the research site.

OpalGenix, IncNCT05452694

Development of a Physiologic Measure of Vincristine Induced Peripheral Neuropathy in Children and Adolescents

The purpose of this study is the development of a physiologic endpoint using a novel technology that would provide an objective, easy to use and more sensitive…

Chemotherapy-induced Peripheral Neuropathy

Estimated

~$10 – $675

Actual pay is set by the research site.

Children's National Research InstituteNCT04786977

Observational

Ultrasound Guided Radiofrequency Ablation of the Occipital Nerve

Study an ultrasound guided approach to radiofrequency ablation of the occipital nerve that makes it possible to see the needle during treatment procedure. It i…

Nerve Pain

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Kansas Medical CenterNCT06583122

Activity Levels in Bone Marrow Transplant Patients

Participants in this study will be receiving a bone marrow transplant. This study is designed to evaluate correlations between activity levels and length of st…

Bone Marrow Transplant

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Michael TomassonNCT04115241

Phase 1

Use of Linaclotide as a Single Agent Colonoscopy Bowel Preparation Regimen; A Pilot Trial

The goal of this clinical trial is to learn if drug Linaclotide can be used as a single agent regimen to adequately prepare bowel for colonoscopy. The main qu…

Patients Scheduled for Colonoscopy

Estimated

~$500 – $7,500

Actual pay is set by the research site.

University of FloridaNCT06692673

Total Cancer Care Protocol: A Lifetime Partnership With Patients Who Have or May be at Risk of Having Cancer (ORIEN)

This is not a treatment study. The overall objective is to develop an improved standard of care through studying blood, tissue, biological, etc. samples, that …

Cancer Risk

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Colorado, DenverNCT03617939

Real World Data Collection With an Investigational Device for Developing and Evaluating the Clinical Performance of Algorithms in Thulium Fiber Laser Procedures

This is a study to collect procedural data during the use of the SOLTIVE™ Premium SuperPulsed Laser System in the treatment of bladder, ureteral, and kidney st…

Calculi, RenalCalculi, UrinaryBenign Prostatic Hyperplasia

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Olympus Corporation of the AmericasNCT07838077

Observational

Safety and Efficacy of NeuroTechR3 System for Upper Extremity Recovery After Stroke

This research aims to understand the feasibility and effectiveness of using the NeuroTechR3 System to improve upper extremity function after stroke.

Stroke

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Brooks RehabilitationNCT07769281

Phase 1

A Phase 1, Open-label, Fixed-sequence Study to Evaluate the Effect of Vimseltinib on P-glycoprotein (P-gp) Inhibition in Healthy Male Participants

The main purpose of this study is to determine the effect of vimseltinib on pharmacokinetics of P-glycoprotein (P-gp) substrate (dabigatran) in healthy male pa…

Healthy Male Participants

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Deciphera Pharmaceuticals, LLCNCT07744802