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Randomized Phase II Selection Study of Ramucirumab and Paclitaxel Versus FOLFIRI in Refractory Small Bowel Adenocarcinoma

This phase II trial studies how well ramucirumab and paclitaxel or the FOLFIRI regimen (leucovorin calcium, fluorouracil, and irinotecan hydrochloride) work in…

Metastatic Small Intestinal AdenocarcinomaStage III Small Intestinal Adenocarcinoma AJCC v8Stage IIIA Small Intestinal Adenocarcinoma AJCC v8+2 more

Estimated

~$75 – $3,000

Actual pay is set by the research site.

SWOG Cancer Research NetworkNCT04205968

Phase 1

VALIENT: Phase 1 Clinical Trial of VorAsidenib in Combination With Lomustine In Patients With rEcurrent IDH-mutaNT Glioma Harboring IDH1 and/or IDH2 Mutations

This phase I study will evaluate the safety and tolerability of vorasidenib in combination with lomustine and determine the recommended combination dose (RCD) …

Recurrent GliomaIDH-mutant Gliomas

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Megan ManticaNCT07629089

Real World Evaluation of the Safety and Effectiveness of BioBrace® Augmentation in Anterior Cruciate Ligament (ACL) Reconstruction Procedures

This research study will evaluate mid-term clinical safety and performance outcomes of the BioBrace® Reinforced Implant when used to augment a tissue graft dur…

ACL Tears

Estimated

~$10 – $1,050

Actual pay is set by the research site.

CONMED CorporationNCT06948591

Observational

Ameliorating Stroke-induced Hemianopia Via Multisensory Training

This study seeks to determine the extent of the visual capabilities that can be restored in hemianopic stroke patients by a multisensory training technique and…

Hemianopia, HomonymousCortical Blindness, Unspecified Side of Brain

Estimated

~$10 – $750

Actual pay is set by the research site.

Wake Forest University Health SciencesNCT05894434

Phase 2

Arterial Destiffening Effects of SGLT2 Inhibition in Veterans With Obesity

The study will assign participants to take either the medication, empagliflozin or a placebo for 12 weeks. The goal of the study is to determine the effects of…

ObesityVascular Health

Estimated

~$75 – $1,800

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT06745063

Phase 2

Placebo-Controlled and Randomized Phase 2 Trial of CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors to Enhance CMV-Specific Immunity and Prevent CMV Viremia in Recipients After Hematopoietic Stem Cell Transplant

This phase II clinical trial tests how well the cytomegalovirus-modified vaccinica Ankara (CMV-MVA) Triplex vaccine given to human leukocyte antigens (HLA) mat…

Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaChronic Lymphocytic Leukemia+7 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

City of Hope Medical Center

Phase 1

Phase Ib, Open-label Study of Add on Therapy With CK0804 in Participants With Myelofibrosis, With Suboptimal Response to Ruxolitinib

To assess the safety and tolerability of CK0804 as add-on therapy in participants with myelofibrosis, with suboptimal response to ruxolitinib

Myelofibrosis

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Cellenkos, Inc.NCT05423691

Phase 2

A Phase 2 Trial of Ivonescimab for Patients With Advanced, Metastatic Salivary Gland Cancers (I-MAC)

The goal of this study is to evaluate the efficacy and safety of Ivonescimab in participants with advanced, metastatic salivary gland cancers. The name of the…

Salivary Gland CancerAdvanced Salivary Gland CarcinomaMetastatic Salivary Gland Cancer+1 more

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Dana-Farber Cancer InstituteNCT06805617

Observational

Comparing Optimized Models of Primary And Specialist Services for Palliative Care

Palliative care (PC) seeks to reduce suffering and improve quality of life for patients with serious illnesses and their families. National guidelines recommen…

Seriously Ill Hospitalized Patients

Estimated

~$10 – $750

Actual pay is set by the research site.

University of PennsylvaniaNCT07224594

Phase 2

Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Precision Medicine Part 3 - Option II

The purpose of this study is to determine if experimental drug treatment improves recovery after TBI as compared to a control (placebo) group. Changes in recov…

Traumatic Brain Injury

Estimated

~$75 – $1,800

Actual pay is set by the research site.

University of California, San FranciscoNCT06790095

Observational

Combining At-Home Transcutaneous Auricular Vagus Nerve Stimulation and Computerized Cognitive Training for Neurocognitive Rehabilitation

The purpose of this study is to investigate whether combining transcutaneous auricular vagus nerve stimulation (taVNS) with computerized cognitive training mig…

Psychosocial Well-beingNeurocognitive FunctionCognitive Complaint+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Medical University of South CarolinaNCT07517237

Phase 2

A Phase 2, Open-Label, Single-Arm Trial to Evaluate IV Rademikibart as an Add-on Treatment for Acute Exacerbation in Participants With Asthma and or COPD With Type 2 Inflammation

A Phase 2, open-label, single-arm trial to evaluate IV rademikibart as an add-on treatment for acute exacerbation in participants with asthma or COPD with type…

Asthma AcuteCOPD Exacerbation Acute

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Connect Biopharm LLCNCT07705737