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27,354 recruiting studies available now

A Phase I First-in-human Clinical Trial to Evaluate the Safety, Pharmacokinetics, and Antiviral Activity of the Broadly Neutralizing Antibody BNT351 in Adults Living Without and With HIV

This study will test the safety and blood levels of the antibody BNT351 in people living without and with human immunodeficiency virus (HIV). This study will a…

HIV -1 Infection

Estimated

~$500 – $11,250

Actual pay is set by the research site.

BioNTech SENCT07392372

Phase 1

Metformin and Muscle Recovery Following ACL Surgery

The purpose of this research study is to determine if Metformin taken after anterior cruciate ligament reconstruction (ACLR) surgery can decrease muscle fibros…

AtrophyInflammationWeakness, Muscle

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of UtahNCT07699367

Phase 2

A Phase 2 Study of Emapalumab for Prevention of Liver Failure in Pediatric Indeterminate Severe Hepatitis Associated With T-Cell Activation: Severe Hepatitis Intervention With Emapalumab for Liver Disease

The goal of this study is to see whether a medicine called emapalumab, a monoclonal antibody, is safe and works well for patients aged 1 year and older who hav…

Hepatitis

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Children's Healthcare of AtlantaNCT07744919

Observational

High-dose Rate (HDR) Brachytherapy Boost With Stereostatic Body Radiation Therapy (SBRT) to Prostate and Pelvic Nodes for the Initial Treatment of Unfavorable Intermediate or Higher Risk Prostate Cancer

The objective of this phase I/II trial is to prospectively evaluate the toxicity and therapeutic efficacy of Stereostatic Body Radiation Therapy (SBRT) to pros…

Prostatic Cancer

Estimated

~$10 – $750

Actual pay is set by the research site.

University of NebraskaNCT05754580

Phase 3

RAPID5: Rapid Acceleration Process for Intensive Treatment of PTSD in 5 Days

Veterans with posttraumatic stress disorder (PTSD) need more effective treatments. Existing options can have limited adherence and can be very time-consuming. …

PTSD

Estimated

~$50 – $1,350

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT07167940

Phase 1

Phase 1b Dose Escalation Trial of OMTX705, an Anti-Fibroblast Activation Protein Antibody-Drug Conjugate, in Combination With Gemcitabine/Nab-Paclitaxel and Tislelizumab in Patients With Advanced/Metastatic Pancreatic Adenocarcinoma

This is a Phase 1b dose escalation trial of OMTX705, an anti-fibroblast activation protein (FAP) antibody-drug conjugate (ADC), in combination with gemcitabine…

Pancreatic Adenocarcinoma Metastatic

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Oncomatryx Biopharma S.L.NCT07377045

Phase 1

Phase I Trial of Ruxolitinib Plus Fostamatinib for the Treatment of Steroid Refractory Chronic Graft Versus Host Disease

This is an open-label phase I study of fostamatinib in combination with ruxolitinib for the treatment of chronic GvHD with a suboptimal response to corticoster…

Chronic Graft Versus Host Disease

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Stefanie Sarantopoulos, MD, PhD.NCT06233110

Phase 2

Effects of Oral Progesterone in Transgender Women on Breast Development, Sleep Quality, Psychological Distress, and Cardiovascular Risk

This study aims to study the effects of Oral Progesterone in Transgender Women. The primary goal is to study the effect of progesterone on psychological distre…

Transgender Women

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Emory UniversityNCT06807580

Randomized, Prospective Controlled Head-to-head Clinical Trial Comparing a Bioengineered Skin Substitute to a Biologically Active Human Skin Allograft for the Treatment of Venous Leg Ulcers.

Given the propensity for venous leg ulcers to become refractory, long standing lesions, incorporating active biologic grafts into the standard compression ther…

Venous Leg Ulcers

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Solsys Medical LLCNCT02047084

Observational

Caregiver-assisted Pain Coping Skills Training for Dementia Pilot Study

The purpose of the study is to develop a caregiver-assisted pain coping skills training program for older adults who have pain and mild to moderate dementia an…

PainDementia, MildDementia, Moderate

Estimated

~$10 – $750

Actual pay is set by the research site.

Duke UniversityNCT06854718

Observational

Osteopathic Manipulative Therapy(OMT) Effects on Post-Acute Sequalae of COVID-19(PASC)

This study is investigating the effects of using an Osteopathic Manipulative Therapy (OMT) treatment protocol that was shown to statistically improve smell in …

Long-COVIDPASCLong COVID Syndrome

Estimated

~$10 – $750

Actual pay is set by the research site.

University of LouisvilleNCT06883513

Phase 1

Wayne Warrior CAnnabis Research and Education: Cannabis and Behavioral Health

This study is a randomized, controlled clinical trial to examine the therapeutic potential of cannabinoids for treating veterans with PTSD and suicidal ideatio…

Post Traumatic Stress DisorderCannabis UseSuicide+2 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Wayne State UniversityNCT06381180